Molecular Diagnosis And Therapy Of Autoimmune Disease Using Translational And Reverse Translational Approaches
Funder
National Health and Medical Research Council
Funding Amount
$2,331,372.00
Summary
We plan to translate our recent discoveries on human gene variants and molecules produced by immune cells (follicular T cells) into effective therapies for autoimmune diseases. This will involve understanding the mechanisms by which the genes and molecules regulate immune tolerance, stratifying patients with autoimmune disease using newly identified biomarkers, trialling existing biologicals according to affected molecular pathway, and taking novel targets through to commercialisation.
Fabrication of silicon solar cells in a Lunar-like vacuum environment. In-situ power generation on the Moon is essential for the advancement of space exploration and habitation. At present this involves transportation of solar cells to the Moon. This proposal aims to pave the way for manufacture of solar cells on the Moon from Lunar materials. Utilising the future extraction and purification of silicon, abundant in lunar regolith, the project will focus on fabrication of silicon solar cells. Thi ....Fabrication of silicon solar cells in a Lunar-like vacuum environment. In-situ power generation on the Moon is essential for the advancement of space exploration and habitation. At present this involves transportation of solar cells to the Moon. This proposal aims to pave the way for manufacture of solar cells on the Moon from Lunar materials. Utilising the future extraction and purification of silicon, abundant in lunar regolith, the project will focus on fabrication of silicon solar cells. This will provide power for: water mining, oxygen extraction, vehicles and habitats on the Moon and delivery of materials to Low Earth Orbit. The proposed research aims to develop solar cells that can be manufactured on the Moon, using materials abundant there, and techniques exploiting the natural vacuum of space.Read moreRead less
Engineering stable, efficient perovskite solar cells. This project aims to address and resolve a critical issue facing perovskite solar cells which have enormous potential as a future technology for the large-scale generation of cheap, clean electricity: their instability under actual operating conditions. The project is expected to make significant fundamental advances in compositional, structural and interface engineering. This project will benefit the environment by paving the way for the wi ....Engineering stable, efficient perovskite solar cells. This project aims to address and resolve a critical issue facing perovskite solar cells which have enormous potential as a future technology for the large-scale generation of cheap, clean electricity: their instability under actual operating conditions. The project is expected to make significant fundamental advances in compositional, structural and interface engineering. This project will benefit the environment by paving the way for the widespread adoption of cheaper and more efficient solar cells.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100812
Funder
Australian Research Council
Funding Amount
$425,888.00
Summary
Is degradation of photovoltaic modules predictable and preventable? This project aims to determine the fundamental properties of the hydrogen related defect causing degradation of commercial solar modules and develop models to predict its impact. The defect causes up to 16% power loss and is likely to affect all photovoltaics due to the universal behaviour of hydrogen in semiconductors. Through new techniques combining deuterium (heavy hydrogen) and machine learning, the key project outcomes are ....Is degradation of photovoltaic modules predictable and preventable? This project aims to determine the fundamental properties of the hydrogen related defect causing degradation of commercial solar modules and develop models to predict its impact. The defect causes up to 16% power loss and is likely to affect all photovoltaics due to the universal behaviour of hydrogen in semiconductors. Through new techniques combining deuterium (heavy hydrogen) and machine learning, the key project outcomes are new knowledge of hydrogen behaviour, mitigation of degradation and predictive models to test and forecast the future output of affected modules. This is critical for system design and reliability, manufacturer warranty terms, investor returns, consumer confidence, and ultimately mitigating the climate crisis.Read moreRead less
Perovskite-silicon tandem solar cells: a pathway to 30 per cent efficiency. This project aims to develop a new type of solar cell that is much more efficient than today’s commercial silicon solar cells. Increasing cell efficiency is one of the most effective ways to reduce the cost of solar electricity, but silicon cells are approaching practical and theoretical limits. This project expects to boost the efficiency of silicon solar cells by adding a low-cost solar cell on top to create a tandem d ....Perovskite-silicon tandem solar cells: a pathway to 30 per cent efficiency. This project aims to develop a new type of solar cell that is much more efficient than today’s commercial silicon solar cells. Increasing cell efficiency is one of the most effective ways to reduce the cost of solar electricity, but silicon cells are approaching practical and theoretical limits. This project expects to boost the efficiency of silicon solar cells by adding a low-cost solar cell on top to create a tandem device. The expected outcome is a solar cell that can convert more than 30 per cent of incident sunlight into electricity, compared to 20-25 per cent for current cells. Developing cheap, high efficiency solar cells should further reduce the cost of solar electricity, and accelerate the uptake of clean energy.Read moreRead less
Advanced metallisation for III-V Photovoltaic Solar Power Systems. This project aims to augment the overall electrical efficiency of concentrator photovoltaic solar systems that provide large-scale generation of cheap, clean electricity. Existing concentrator solar cells are highly efficient (>40%) but their performance is hampered by thick front-metal contacts that shade the cell. The project is expected to develop a new concentrator solar cell metalisation and insulation technology. The benefi ....Advanced metallisation for III-V Photovoltaic Solar Power Systems. This project aims to augment the overall electrical efficiency of concentrator photovoltaic solar systems that provide large-scale generation of cheap, clean electricity. Existing concentrator solar cells are highly efficient (>40%) but their performance is hampered by thick front-metal contacts that shade the cell. The project is expected to develop a new concentrator solar cell metalisation and insulation technology. The benefit of the project will be a direct increase in the system efficiency and simplified manufacturing of the concentrator solar receiver, which in turn reduces the cost of the concentrator power plant constructed by our Australian project partner RayGen Resources Pty Ltd.Read moreRead less
Hot carrier cooling mechanisms in nano structures. This project aims to systematically investigate possible mechanisms of hot carrier cooling in nano structures and to identify the most dominant mechanisms. These are important for efficient hot carrier solar cells and thermoelectrics. This project will develop new physics to understand hot carrier dynamics in nano structures. This project is expected to result in photovoltaic systems with a lower balance of system and levelised cost of electrici ....Hot carrier cooling mechanisms in nano structures. This project aims to systematically investigate possible mechanisms of hot carrier cooling in nano structures and to identify the most dominant mechanisms. These are important for efficient hot carrier solar cells and thermoelectrics. This project will develop new physics to understand hot carrier dynamics in nano structures. This project is expected to result in photovoltaic systems with a lower balance of system and levelised cost of electricity compared to conventional technologies. This should boost solar industry, create green jobs and reduce greenhouse gas emissions.Read moreRead less
Revival of silicon solar cells for space applications. Development of very thin silicon solar cells for space applications. These space cells will include many of the significant improvements in silicon cells of the last 20 years, which have allowed close to the maximum possible efficiencies and the order of magnitude decrease in cost of terrestrial solar cells. Space cells require good radiation resistance to give good end of life performance. This project will use photovoltaic architectures, p ....Revival of silicon solar cells for space applications. Development of very thin silicon solar cells for space applications. These space cells will include many of the significant improvements in silicon cells of the last 20 years, which have allowed close to the maximum possible efficiencies and the order of magnitude decrease in cost of terrestrial solar cells. Space cells require good radiation resistance to give good end of life performance. This project will use photovoltaic architectures, proven to give high performance for terrestrial cells, to develop ultrathin silicon cells with extreme light trapping and improved radiation tolerance to give high beginning and end of life efficiencies. These cells will be less than 5% of the cost of multijunction cells currently used in space.Read moreRead less