Co-evolution of the host pathogen interaction between Leptosphaeria maculans and Brassica species. Brassica canola is Australia's third largest export crop, producing 13% of the world's canola oil. However, blackleg disease, caused by the fungus Leptospheria maculans leads to annual yield losses of 15%, with 100% loss associated with breakdown of resistance. International investment has provided novel genome resources for Brassica and L. maculans. Applying these resources to understand the co-ev ....Co-evolution of the host pathogen interaction between Leptosphaeria maculans and Brassica species. Brassica canola is Australia's third largest export crop, producing 13% of the world's canola oil. However, blackleg disease, caused by the fungus Leptospheria maculans leads to annual yield losses of 15%, with 100% loss associated with breakdown of resistance. International investment has provided novel genome resources for Brassica and L. maculans. Applying these resources to understand the co-evolution of this plant-fungal interaction could prevent the current boom-bust cycle of canola production in Australia. This study will also provide a model and knowledge base for applications in other species, leading to enhanced crops with increased plant protection and robust, reliable productivity.Read moreRead less
Systemic gene silencing in Arabidopsis, and relevance to plant biology. Gene silencing is a highly conserved process in plants and animals. It is of fundamental importance to gene regulation, virus defence, genome response to environment, and genome evolution. Remarkably, when gene silencing is triggered in plants it can spread throughout the organism. The aim of this project is to define the mechanism of intercellular movement of gene silencing in plants, and its relevance to plant growth and d ....Systemic gene silencing in Arabidopsis, and relevance to plant biology. Gene silencing is a highly conserved process in plants and animals. It is of fundamental importance to gene regulation, virus defence, genome response to environment, and genome evolution. Remarkably, when gene silencing is triggered in plants it can spread throughout the organism. The aim of this project is to define the mechanism of intercellular movement of gene silencing in plants, and its relevance to plant growth and defence against pathogens. Expected outcomes include increased understanding of intercellular genetic signalling in plants and its role in plant growth and disease resistance. The findings may also shed new light on mechanisms of gene silencing in animals.Read moreRead less
Mediator: a new concept for controlled gene expression in plant biotechnology. The Mediator protein complex is a new control point for the activation of all genes in higher organisms and the purpose of this project is to understand how three Mediator subunits regulate disease resistance in plants. The outcomes provide a new concept to direct natural gene expression towards robust crop plants able to cope with climatic variations.