Equity and diversity in the Australian architecture profession: women, work, and leadership. This project will develop strategies to maximize women's participation in architecture, improving human resource practices within architectural firms and developing a diversity policy for the national professional association. Together these outcomes will increase women's representation within architecture, and help all architects achieve a greater work life balance with its concomitant effects of improv ....Equity and diversity in the Australian architecture profession: women, work, and leadership. This project will develop strategies to maximize women's participation in architecture, improving human resource practices within architectural firms and developing a diversity policy for the national professional association. Together these outcomes will increase women's representation within architecture, and help all architects achieve a greater work life balance with its concomitant effects of improving individual health, wellbeing and national productivity. Increasing the visibility and recognition of female architects will directly support innovative practice in architecture, which will advantage all attempts to create socially and ecologically sustainable built environments in Australia.Read moreRead less
Exploring synergies with innovative Green Technologies for Advanced Renovation: Redefining a Bioclimatic approach for multi residential and office buildings in warmer climates. Building energy consumption accounts for nearly 27% of all energy related greenhouse gas emissions. By 2010, emissions' from buildings is estimated to increase by 48% above 1990 levels. This projected trend is alarming given that Australia's obligation under the Kyoto Protocol is only 8% above 1990 levels. Renovation of e ....Exploring synergies with innovative Green Technologies for Advanced Renovation: Redefining a Bioclimatic approach for multi residential and office buildings in warmer climates. Building energy consumption accounts for nearly 27% of all energy related greenhouse gas emissions. By 2010, emissions' from buildings is estimated to increase by 48% above 1990 levels. This projected trend is alarming given that Australia's obligation under the Kyoto Protocol is only 8% above 1990 levels. Renovation of existing buildings is necessary to achieve this target. Research will address this problem by providing principles, strategies and solutions demostrating improvement of environmental performance and cost benefits. The application of new principles will assist with transforming the building industry to meet Kyoto targets.Read moreRead less
Towards a Quality of Life Model for Sustainable Housing in South East Queensland. Current reports, on Quality of Life in South East Queensland and the Queensland Governments State of the Environment demonstrate a paradox, - high quality of life but also increasing environmental impact. How to address this paradox is a major research question addressed in this project. Through examining examples of best practice sustainable housing it is possible to address this question. The key factors of quali ....Towards a Quality of Life Model for Sustainable Housing in South East Queensland. Current reports, on Quality of Life in South East Queensland and the Queensland Governments State of the Environment demonstrate a paradox, - high quality of life but also increasing environmental impact. How to address this paradox is a major research question addressed in this project. Through examining examples of best practice sustainable housing it is possible to address this question. The key factors of quality of life will be identified for housing, which will assist policy makers plan for a sustainable future. Read moreRead less
Understanding the lessons of Australia's Gold Coast through the late 20th century debate on criticality and instrumentality in architecture. This project will investigate the role of architecture in the western city through problems in 20th century architectural theory. It will show how the Gold Coast offers new insights into contemporary architecture and will result in two closely related books: an architectural history of the Gold Coast; and a new account of contemporary architectural theory.
Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions w ....Making better decisions about built assets: learning by doing. This research will assist the built environment professions and their clients to make better decisions about new developments through a novel 'learning by doing' approach. Used successfully in other fields such as natural resource management, this idea will capitalise on the large number of asset investments undertaken to benchmark original stakeholder intentions and aspirations against the reality of current performance. Decisions will be re-evaluated in the context of contemporary economic, social and environmental criteria to enable existing multi-criteria models to deliver more sustainable outcomes that are also feasible and in the national interest, and consequently minimise the industry's current exposure to future climate change.Read moreRead less
Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Austra ....Carbon neutral communities: making the transition. This project has well defined National benefits, both economic and social, for the collaborative partners, the business community, policy makers, community groups and the broader Australian community. It contributes toward NRP 1, through developing practical measures for reducing GHG emissions in Australian urban areas, and strategies for overcoming barriers to greater uptake of energy efficiency and alternative technologies; and helping Australia to meet its greenhouse reduction targets. The project economic benefits to through energy savings; stimulating innovation in urban design, building design and transport use; promoting new business opportunities; and encouraging more sustainable lifestyle decisions. Read moreRead less
Campus: Building Modern Australian Universities. This project plans to examine the post-World War Two evolution of the Australian university campus. Modern campuses created opportunities for the realisation of innovative solutions in urban planning, architecture and landscape. The project plans to reveal the physical impacts of political, institutional, social and cultural demands through comparative thematic investigation, digital visualisation and detailed case studies. Foregrounding landscape ....Campus: Building Modern Australian Universities. This project plans to examine the post-World War Two evolution of the Australian university campus. Modern campuses created opportunities for the realisation of innovative solutions in urban planning, architecture and landscape. The project plans to reveal the physical impacts of political, institutional, social and cultural demands through comparative thematic investigation, digital visualisation and detailed case studies. Foregrounding landscape and site, the project aims to establish new historical knowledge, identify campuses as catalysts for urban thinking, and demonstrate strategies for their conservation and adaptation to meet future needs in the tertiary sector.Read moreRead less
Role Of IGF Binding Protein-3 (IGFBP-3) And IGFBP-5 As Modulators Of Nuclear Hormone Signalling
Funder
National Health and Medical Research Council
Funding Amount
$465,750.00
Summary
The insulin-like growth factors are small proteins involved in the growth of most tissues. Their actions are regulated by binding to larger proteins (known as IGFBPs) in the bloodstream and outside the cell. However, some IGFBPs are also found inside cells, where they seem to carry out other functions. We believe that two of these binding proteins, IGFBP-3 and IGFBP-5, change the way cells respond to vitamin A and vitamin D. These two vitamins are important in cell growth and in the way certain ....The insulin-like growth factors are small proteins involved in the growth of most tissues. Their actions are regulated by binding to larger proteins (known as IGFBPs) in the bloodstream and outside the cell. However, some IGFBPs are also found inside cells, where they seem to carry out other functions. We believe that two of these binding proteins, IGFBP-3 and IGFBP-5, change the way cells respond to vitamin A and vitamin D. These two vitamins are important in cell growth and in the way certain cells perform specialised functions. In test-tube experiments, IGFBP-3 and IGFBP-5 interact directly with the receptors that regulate the effects of these hormones. If the same thing happens inside the cell, IGFBP-3 and IGFBP-5 could change the way these receptors respond to signals from outside the cell. We will investigate what effect these IGFBPs have in living cells and in whole animals and how this may relate to human disease. If we are able to understand how IGFBP-3 and IGFBP-5 affect the way cells respond to vitamin A and D, then we may be able to develop new ways to treat certain human diseases.Read moreRead less
Whole Body Vibration For Osteoporosis: Shaking Up Our Treatment Options
Funder
National Health and Medical Research Council
Funding Amount
$961,017.00
Summary
Our aim is to examine the ability of vibration alone and in combination with osteoporosis drugs to reduce hip fracture in postmenopausal women. In Australia, 1 in 2 women >60yrs, will sustain an osteoporotic fracture. Only drugs notably decrease fracture; however none are entirely effective and some patients don’t respond. Whole body vibration has emerged as a potentially effective therapy. A combination of vibration and drugs may enhance the effects of both and revolutionise treatment.
Why Is The Bone Marrow A “hot-spot” For Myeloma Plasma Cell Metastasis: Are There Gremlins In The System?
Funder
National Health and Medical Research Council
Funding Amount
$651,979.00
Summary
Most cancer patients die because their cancer spreads from a primary site to other tissues in the body. Once escaping the primary site, 70% of all tumours will spread to bone. This raises the question, why is bone a preferred destination for cancer cells? We provide evidence that Gremlin1, made by non-cancer cells within bone, is a key protein that supports cancer growth. This study will examine whether inhibiting Gremlin1 is a potential therapy to inhibit cancer spreading to bone.