Surface Modification of Spray-Dried Powders By Surface-Active Proteins. Internal wall deposits in spray dryers lead to product degradation and pose fire hazards. This situation has limited the manufacturing of high value bio-food powders by the Australian bio-food and dairy industry, which exports 13% of the milk powder in the world. The specific economic benefits to Australia from this project arise from innovative surface modification of powder particles by proteins, development of scientific ....Surface Modification of Spray-Dried Powders By Surface-Active Proteins. Internal wall deposits in spray dryers lead to product degradation and pose fire hazards. This situation has limited the manufacturing of high value bio-food powders by the Australian bio-food and dairy industry, which exports 13% of the milk powder in the world. The specific economic benefits to Australia from this project arise from innovative surface modification of powder particles by proteins, development of scientific instruments and predictive tools based on Computational Fluid Dynamics (CFD). These outcomes will lead to production of free flowing powders from bio-food materials.Read moreRead less
Nucleotides for bioelectronics. Bioelectronics is a key component of nanobiotechnology, a new field that merges the science of biological molecules (DNA, proteins etc.) with electronics and semiconductor physics. We have recently introduced redox-labelled nucleotides that enable the production of electrochemically-active DNA and RNA for genetic, forensic and nanotechnology applications. This project further develops redox nucleotides for use in electronic devices.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0453400
Funder
Australian Research Council
Funding Amount
$110,040.00
Summary
The Roboocyte™: a medium-throughput, secondary functional, screening facility. Changes in ion channel function have been implicated in a wide variety of human diseases. For this reason many researchers are studying ion channels to understand how they work and how they can develop new drug treatments. The slowest step in evaluating the biological activity of compounds is testing them against the ion channels and the current technology requires much tedious manual handling and extensive operator e ....The Roboocyte™: a medium-throughput, secondary functional, screening facility. Changes in ion channel function have been implicated in a wide variety of human diseases. For this reason many researchers are studying ion channels to understand how they work and how they can develop new drug treatments. The slowest step in evaluating the biological activity of compounds is testing them against the ion channels and the current technology requires much tedious manual handling and extensive operator expertise. The Roboocyte facility will triple testing productivity by allowing for the rapid and automated screening of large libraries of compounds. Such a facility will be unique to the Southern Hemisphere.Read moreRead less
Compact Low-Cost Tunable UV Lasers for Biosensing Applications. Detection and characterisation of micro-organisms such as airborne biological agents, parasites in domestic water supplies and micro-organisms used in the food and beverage industry, is of national importance. All biological systems have rich absorption signatures in the UV enabling detection of biological specimens with high sensitivity and selectivity using optical methods. For these applications compact and inexpensive tunable U ....Compact Low-Cost Tunable UV Lasers for Biosensing Applications. Detection and characterisation of micro-organisms such as airborne biological agents, parasites in domestic water supplies and micro-organisms used in the food and beverage industry, is of national importance. All biological systems have rich absorption signatures in the UV enabling detection of biological specimens with high sensitivity and selectivity using optical methods. For these applications compact and inexpensive tunable UV lasers are required; however to date tunable UV lasers have been limited to bulky and expensive systems. We propose to engineer novel, low cost, compact, tunable UV cerium lasers and demonstrate their applicability to selective optical detection of micro-organisms.Read moreRead less
Nanolayer Degradation Deposits on Cold Rolled Steel Strip: The Influence of Rolling Oil Emulsions in Sequential Oxidative and Reductive Environments. Cold rolled steel strip, produced by BHP Steel, is a precursor material for production of internationally recognised Australian products ZINCALUMER Steel and COLORBONDR Steel. Lubricating oils supplied by Quaker Chemical are used during the cold rolling process. When exposed to the direct fired annealing process, nanolayer surface residues can de ....Nanolayer Degradation Deposits on Cold Rolled Steel Strip: The Influence of Rolling Oil Emulsions in Sequential Oxidative and Reductive Environments. Cold rolled steel strip, produced by BHP Steel, is a precursor material for production of internationally recognised Australian products ZINCALUMER Steel and COLORBONDR Steel. Lubricating oils supplied by Quaker Chemical are used during the cold rolling process. When exposed to the direct fired annealing process, nanolayer surface residues can develop from rolling oil films and adversely affect subsequent steel surface wetting by the molten zinc alloy. This collaborative research project will investigate the fundamental nature of nanolayer residue formation, using advanced thermal and surface analysis techniques, with the aim of determining the factors influencing residue formation and reducing their impact.Read moreRead less
Macromolecular Self-Assembly of Amyloid Fibrils. The misfolding of proteins is a key issue in public health. Common diseases, such as Alzheimer's disease, type 2 diabetes, and heart disease are associated with protein misfolding, and have a major impact on society. The use of proteins as therapeutic drugs is now common ( e.g. as vaccines, for immune disorders) but they can be rendered ineffective or harmful by protein misfolding. Through this project, we will enhance the fundamental understandin ....Macromolecular Self-Assembly of Amyloid Fibrils. The misfolding of proteins is a key issue in public health. Common diseases, such as Alzheimer's disease, type 2 diabetes, and heart disease are associated with protein misfolding, and have a major impact on society. The use of proteins as therapeutic drugs is now common ( e.g. as vaccines, for immune disorders) but they can be rendered ineffective or harmful by protein misfolding. Through this project, we will enhance the fundamental understanding of the processes of protein assembly in solution, at solid surfaces, and under shear.
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Modifying and Improving Porous Sol-Gel Materials for Water Purification. XeroCoat is commercialising nanotechnology research out of UQ's Physics department. XeroCoat has received much local and international interest in its signature product 'XeroCoat'. The company is rapidly expanding and has established new research facilities with production facilities to be set-up. This will result in high technology, employment growth for Australia. Links with Flinders could see expansion into SA. The c ....Modifying and Improving Porous Sol-Gel Materials for Water Purification. XeroCoat is commercialising nanotechnology research out of UQ's Physics department. XeroCoat has received much local and international interest in its signature product 'XeroCoat'. The company is rapidly expanding and has established new research facilities with production facilities to be set-up. This will result in high technology, employment growth for Australia. Links with Flinders could see expansion into SA. The company operates in 'Sol-Gel' nanotechnology, which has huge global, academic and commercial interest. However in Australia this technology has only been serviced by Flinders, ANSTO and ANSTO's spin-out company Ceramisphere. The project will help to build a new Australian high tech industry in sol-gel nanotechnology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775720
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
State-of-the-art high resolution thermal analysis suite for the life and material sciences. The facility, unique in Australia, will ensure that Australia will retains in a leading position in these research fields, will provide a basis to be competitive in international funding and support postgraduate training. The acquired equipments will strengthen the already existing infrastructures, enhancing understanding of intrinsic physico-chemical characteristic of various materials, to benefit the co ....State-of-the-art high resolution thermal analysis suite for the life and material sciences. The facility, unique in Australia, will ensure that Australia will retains in a leading position in these research fields, will provide a basis to be competitive in international funding and support postgraduate training. The acquired equipments will strengthen the already existing infrastructures, enhancing understanding of intrinsic physico-chemical characteristic of various materials, to benefit the community such as characterising functional nanomaterials for high-tech technologies and use of inhalation aerosol drug delivery to benefit patients with respiratory diseases for an improved therapeutic and health outcome.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668019
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
An Advanced Computed Tomography Facility - high capacity and high resolution for dynamic studies in porous and granular materials. Characterising complex materials in 3D is an emerging discipline which is driving design concepts for new materials and assists in understanding properties of real world materials. The ANU/UNSW collaboration has developed an internationally recognized program in this emerging discipline and successfully applied the technology to applications in the oil and gas indust ....An Advanced Computed Tomography Facility - high capacity and high resolution for dynamic studies in porous and granular materials. Characterising complex materials in 3D is an emerging discipline which is driving design concepts for new materials and assists in understanding properties of real world materials. The ANU/UNSW collaboration has developed an internationally recognized program in this emerging discipline and successfully applied the technology to applications in the oil and gas industry, groundwater remediation, tissue engineering, medical diagnosis of osteoporosis, granular packing and the design of new materials. The present application will give the collaboration the ability to study a larger number of systems and to image the dynamics of materials in 3D. This will significantly broaden the impact and scope of the applications of this new technology.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775513
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Advanced Process Tomography Research Facility for Multiphase System Studies. The establishment of an advanced process tomography facility at UNSW has several important national benefits, including; increased capacity of the collaborating institutions to train highly qualified personnel to meet new and growing demands in the processing industries; the transfer of research-based cheap and efficient technologies to our industries to enhance their position in a competitive global market; the improve ....Advanced Process Tomography Research Facility for Multiphase System Studies. The establishment of an advanced process tomography facility at UNSW has several important national benefits, including; increased capacity of the collaborating institutions to train highly qualified personnel to meet new and growing demands in the processing industries; the transfer of research-based cheap and efficient technologies to our industries to enhance their position in a competitive global market; the improvement in our culture and living standards through superior and inexpensive food, biomedical, water, environmental, materials and military products; and the strengthening of Australian position, through international linkage projects, as a world leader in the development of novel processing technologies.Read moreRead less