The Epidemiology And Control Of Sexually Transmitted Infections Within Australia.
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
Sexually transmitted infections (STIs) such as chlamydia are increasing. Without effective vaccines, STIs can only be controlled by behavioral or screening interventions. This program of research will help us understand how STIs such as chlamydia, Mycoplasma genitalium, HPV and bacterial vaginosis spread among Australians and will help us to determine how best to control them.
Allergies And Chronic Respiratory Diseases: Causes, Biological Pathways And Interventions
Funder
National Health and Medical Research Council
Funding Amount
$420,872.00
Summary
Allergies and chronic respiratory diseases are major causes of illness and death in Australia. Worryingly there are still many gaps in knowledge on how best to prevent and manage these diseases. The proposed program will investigate these questions and provide evidence to guide health policy and clinical management. As this program is built on state-of the-art methods and technology, these original Australian findings will be of great importance internationally.
How Genetic And Environmental Risk Factors Interactively Impact On Animal Models For Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$387,489.00
Summary
The proposed research will clarify to what degree a genetic predisposition to schizophrenia alters the response to environmental risk factors (e.g. social stress and drugs of abuse) or interacts with them. Further, it will provide more sophisticated animal models for schizophrenia as well as better tools to validate these models. These studies may offer novel genetic and molecular clues to help explain the interactive nature of the impact genetic and environmental factors have on schizophrenia.
Enhancing Understanding Of The Combined Influence Of Physical Activity And Sleep As CVD Risk Factors
Funder
National Health and Medical Research Council
Funding Amount
$476,728.00
Summary
Physical activity and sleep both impact health but are rarely considered as joint influences of health. I lead a research group that combines epidemiology and intervention research to generate unique insights to better understand how these behaviours jointly impact health and develop, evaluate and disseminate interventions to improve these behaviours.
Improving Child Health Outcomes In Common, High Burden Conditions.
Funder
National Health and Medical Research Council
Funding Amount
$279,895.00
Summary
As medical advances over the past 50 years have helped to reduce traditional childhood illnesses such as infections, behavioural, developmental and mental health problems have increased. These problems affect at least 1 in 5 Australian children yet the vast majority of problems go undetected and untreated. I propose to develop, trial and disseminate evidence-based approaches to common child health problems including mental health and sleep problems.
Understanding Adolescent Neurodevelopment: Relevance To Schizophrenia
Funder
National Health and Medical Research Council
Funding Amount
$447,928.00
Summary
Schizophrenia first appears clinically during late adolescence. This project seeks to understand the molecular changes that occur during adolescent brain development that may underlie the behavioural abnormalities found in schizophrenia. We will focus on Brain derived neurotrophic factor (BDNF), a gene which when reduced is associated with schizophrenia. By examining the role of this gene during adolescent brain development, we will better understand how disruptions to this gene may lead to schi ....Schizophrenia first appears clinically during late adolescence. This project seeks to understand the molecular changes that occur during adolescent brain development that may underlie the behavioural abnormalities found in schizophrenia. We will focus on Brain derived neurotrophic factor (BDNF), a gene which when reduced is associated with schizophrenia. By examining the role of this gene during adolescent brain development, we will better understand how disruptions to this gene may lead to schizophrenia-like behaviours in adulthood.Read moreRead less