Sirtuins And The Molecular Epidemiology Of Frailty In Older Men
Funder
National Health and Medical Research Council
Funding Amount
$483,246.00
Summary
People in Australia are living longer and longer and yet little is known about the underlying biology of the ageing process. This project will investigate the role of a number of molecular and cellular factors in the aetiology of frailty in a group of more than 1400 older men who are already participating in the Concord Health and Ageing in Men Project. A particular focus of the project are sirtiuns, a group of enzymes recently found to be associated with longer life in several animal models.