Oyster adaptation to climate change via transgenerational plasticity. We are in an age of rapid climate change, where the need to understand the adaptive potential of marine organisms in warmer, more acidified oceans is increasingly urgent. This is especially true in Australia where changes are significant. This project uses a cutting-edge, integrated interdisciplinary approach to measure the capacity of oysters to adapt and persist to climate change via transgenerational plasticity, describe th ....Oyster adaptation to climate change via transgenerational plasticity. We are in an age of rapid climate change, where the need to understand the adaptive potential of marine organisms in warmer, more acidified oceans is increasingly urgent. This is especially true in Australia where changes are significant. This project uses a cutting-edge, integrated interdisciplinary approach to measure the capacity of oysters to adapt and persist to climate change via transgenerational plasticity, describe the epigenetic mechanisms which underlie it and develop an immediate breeding method to protect vulnerable oysters and other marine organisms against climate change. The research outcomes will transform Indigenous-led oyster reef restoration projects and future-proof an iconic food source and national industry.Read moreRead less
Turning back the clock on brain cell aging. This proposal aims to determine the role of fundamental epigenetic mechanisms in the process of aging and whether modulation of the epi-genome underpins an improvement in cognitive function. It combines the fields of epigenetics, neurosciences and mathematics to delineate the dynamics of DNA methylation and histone modification marking on the transcriptome during normal, healthy aging. The outcomes will provide significant new knowledge of the variable ....Turning back the clock on brain cell aging. This proposal aims to determine the role of fundamental epigenetic mechanisms in the process of aging and whether modulation of the epi-genome underpins an improvement in cognitive function. It combines the fields of epigenetics, neurosciences and mathematics to delineate the dynamics of DNA methylation and histone modification marking on the transcriptome during normal, healthy aging. The outcomes will provide significant new knowledge of the variable cognitive decline that occurs in healthy aging and why some populations age less successfully than others do. Better understanding of the impact of environmental change on the biology of aging has potential community benefits.Read moreRead less
The basis of oyster resilience to global environmental change. This project aims to investigate the impact of global environmental change on the survival of Australia’s oyster industry, by combining the science of genetics, physiology and ecology to identify already resilient oysters. Through the first complete understanding of resilience in oysters, including the trade-offs they have made in other fitness traits, the project develops new capacities to 'climate and future-proof' our natural oyst ....The basis of oyster resilience to global environmental change. This project aims to investigate the impact of global environmental change on the survival of Australia’s oyster industry, by combining the science of genetics, physiology and ecology to identify already resilient oysters. Through the first complete understanding of resilience in oysters, including the trade-offs they have made in other fitness traits, the project develops new capacities to 'climate and future-proof' our natural oyster populations and the Australian oyster industry, to enable the restoration of degraded oyster habitats. This project will ensure the future of an iconic and economically important national industry and food source and contribute to preserving the critical cultural links of Indigenous Australians with their lands.Read moreRead less