Predicting seed lifespan for improved curation of conservation seed banks. This project aims to improve the practice of seed banking for the conservation of the Australian flora. Recent evidence points to diverse and complex storage behaviour for wild seeds and to seeds of many species being shorter-lived than anticipated. Predicting seed storage behaviour and viability decline is central to effective seedbanking. This project expects to develop new high throughput technologies and data interrog ....Predicting seed lifespan for improved curation of conservation seed banks. This project aims to improve the practice of seed banking for the conservation of the Australian flora. Recent evidence points to diverse and complex storage behaviour for wild seeds and to seeds of many species being shorter-lived than anticipated. Predicting seed storage behaviour and viability decline is central to effective seedbanking. This project expects to develop new high throughput technologies and data interrogation techniques for predicting seed lifespan in storage, and alternative storage protocols for problematic seeds. Results will allow seed bank managers to more efficiently triage and curate their seed collections and will benefit seed banks globally.Read moreRead less
Genomes on islands: Improving management of Australia's threatened mammals. This project aims to improve the management of endangered mammals by combining data on genomic and morphological variation with results from conservation translocations. Using new genomics methods, the project will measure the effects of small population size on genetic diversity and mutation load, in extinct as well as remnant and translocated populations. The project will monitor seven intensively managed marsupial spe ....Genomes on islands: Improving management of Australia's threatened mammals. This project aims to improve the management of endangered mammals by combining data on genomic and morphological variation with results from conservation translocations. Using new genomics methods, the project will measure the effects of small population size on genetic diversity and mutation load, in extinct as well as remnant and translocated populations. The project will monitor seven intensively managed marsupial species to better understand how to mix populations for fauna restoration projects. This project should improve methods to promote species recovery in Australia and globally.Read moreRead less
Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the rel ....Adaptation to life in the dark: genomic analyses of blind beetles. This project aims to utilise a unique Australian model system based on multiple, independently-evolved subterranean water beetles to explore the adaptive and regressive changes in the genome that occur when surface species colonise subterranean habitats. This project focuses on the evolution of Heat Shock protein (Hsp) genes that play critical roles in adaptation to environmental stress and the process of de-canalisation, the release of cryptic genetic variation that can allow novel morphologies to evolve in new environments. The project expects to provide further understanding of how species may potentially adapt to environmental stresses in the future, including climate change.Read moreRead less
Is regressive evolution associated with loss of gene function in subterranean animals? This project aims to investigate a fundamental biological process: the evolutionary basis for how non-functional characters, such as eyes in subterranean animals, are lost. It will use a unique model system based on eyeless water beetles, and utilise novel new genomic tools to test whether loss of characters results from gene inactivation.
How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex ....How are visual gene pathways lost and restored during reptile evolution? This project aims to investigate how complex traits are lost during evolution, and once lost if they can be regained. The project will use the diverse visual systems of snakes and lizards to shed light on the process of gene loss in degenerative lineages, and discover the mechanisms that compensate for gene losses in taxa with secondarily evolved visual capabilities- providing a case of evolutionary re-innovation in complex traits.Read moreRead less
Physiology of oxygen transport in the mammalian kidney. This project aims to improve understanding of oxygen regulation in renal tissue and knowledge of the physiology of the kidney. The mammalian kidney receives more oxygen than it uses or needs, and yet renal tissue is commonly found to be hypoxic. This project proposes that oxygen transport to the renal tissue is limited by blood vessel surface area. The project expects to generate anatomical data currently missing from the renal physiology c ....Physiology of oxygen transport in the mammalian kidney. This project aims to improve understanding of oxygen regulation in renal tissue and knowledge of the physiology of the kidney. The mammalian kidney receives more oxygen than it uses or needs, and yet renal tissue is commonly found to be hypoxic. This project proposes that oxygen transport to the renal tissue is limited by blood vessel surface area. The project expects to generate anatomical data currently missing from the renal physiology community, and potentially change the accepted story of oxygen homeostasis in the kidney. This will provide significant benefits, such as the provision of the foundational physiological science behind a determinant of kidney health and its flow-on impact to quality of life.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989374
Funder
Australian Research Council
Funding Amount
$550,000.00
Summary
South Australian High-Resolution and Ion-Mobility Mass Spectrometry Facility. The analytical facility will enhance (i) fundamental research to understand the mechanisms of the reactions of charged species with neutral molecules, and (ii) the provision of structural information, including the precise atomic composition of any molecule, small or large. Research supported by this facility includes (a)nanotechnology, including supramolecular chemistry, (b) bioscience: cancer research, neurodegenera ....South Australian High-Resolution and Ion-Mobility Mass Spectrometry Facility. The analytical facility will enhance (i) fundamental research to understand the mechanisms of the reactions of charged species with neutral molecules, and (ii) the provision of structural information, including the precise atomic composition of any molecule, small or large. Research supported by this facility includes (a)nanotechnology, including supramolecular chemistry, (b) bioscience: cancer research, neurodegenerate diseases (e.g. Parkinson's disease) osteoarthritis, inflammation, cardiac diseases and synthetic approaches to anticancer and other drugs.Read moreRead less
Innovative approaches to managing and understanding taste and odour in drinking water systems. Taste and odour (T/O) problems resulting from Cyanobacteria can change consumers' perception of product safety, resulting in many complaints, soaring management and treatment costs, and large financial losses, yet little is known about how they arise.
This project will provide the Australian Water Industry with cost-effective, sensitive, specific, rapid and practical tools for managing and understandi ....Innovative approaches to managing and understanding taste and odour in drinking water systems. Taste and odour (T/O) problems resulting from Cyanobacteria can change consumers' perception of product safety, resulting in many complaints, soaring management and treatment costs, and large financial losses, yet little is known about how they arise.
This project will provide the Australian Water Industry with cost-effective, sensitive, specific, rapid and practical tools for managing and understanding T/O episodes, and will also benefit the aquaculture and food sectors, and the research community. An improved ability to manage geosmin in drinking water, will also have positive repercussions on the Australian environment, by eliminating the need to use environmentally controversial control methods such as copper sulphate dosing.
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Fertility Management of Koalas, Kangaroos and Wallabies. The aims of this work are to test a commercially available long-acting contraceptive on large populations of kangaroos and koalas, and to devise efficient, economic and practical ways of delivering these contraceptives to the animals. The outcome will be a system of controlling the number of these animals which is economically realistic and acceptable to national and international communities. The contraceptive is administered as a small, ....Fertility Management of Koalas, Kangaroos and Wallabies. The aims of this work are to test a commercially available long-acting contraceptive on large populations of kangaroos and koalas, and to devise efficient, economic and practical ways of delivering these contraceptives to the animals. The outcome will be a system of controlling the number of these animals which is economically realistic and acceptable to national and international communities. The contraceptive is administered as a small, subcutaneous implant in the back of the neck. It can be inserted very quickly and has no harmful side effects. A further outcome may be its adoption in other parts of the world, to the advantage of the company which manufactures it.Read moreRead less
Scaling of structure, function and energetics of the vertebrate cardiovascular system. The hearts of mammals, reptiles and fish do different amounts of work, depending on the animal’s metabolic rate and body size. This project attempts to understand why hearts are the size and thickness that they are, and whether this results in minimising the work necessary to satisfy the requirements of the animal.