Predictability in evolution: From behaviour to genome. This project aims to determine whether evolution is primarily unpredictable and stochastic, or predictable and constrained along certain pathways. By using a natural experiment that caused wood-feeding cockroaches to evolve into soil-burrowing cockroaches in response to climate change millions of years ago, this project will determine how the genomes of these organisms responded. This will show whether the same molecular changes are repeated ....Predictability in evolution: From behaviour to genome. This project aims to determine whether evolution is primarily unpredictable and stochastic, or predictable and constrained along certain pathways. By using a natural experiment that caused wood-feeding cockroaches to evolve into soil-burrowing cockroaches in response to climate change millions of years ago, this project will determine how the genomes of these organisms responded. This will show whether the same molecular changes are repeatedly used in the evolution of complex traits, including burrow construction. This will contribute to the understanding of how predictable evolution is at the molecular level, and provide insights into how genomes change in response to prolonged climate change.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160100614
Funder
Australian Research Council
Funding Amount
$363,612.00
Summary
Evolutionary genomics and origin of the molluscan biomineralisation toolkit. The project aims to use new genomes from understudied lineages of Mollusca to identify the genes involved in shell formation (biomineralisation) and infer their function and evolutionary history. The ability of molluscs to biofabricate intricate and robust skeletal structures from sea water is encoded in their genomes. Understanding the ancestral biomineralisation toolkit is of great interest to materials science, which ....Evolutionary genomics and origin of the molluscan biomineralisation toolkit. The project aims to use new genomes from understudied lineages of Mollusca to identify the genes involved in shell formation (biomineralisation) and infer their function and evolutionary history. The ability of molluscs to biofabricate intricate and robust skeletal structures from sea water is encoded in their genomes. Understanding the ancestral biomineralisation toolkit is of great interest to materials science, which seeks to replicate molluscan biomineralisation in vitro for biomedical and other applications. Understanding the toolkit is an important first step toward synthetic biology techniques to 'print' structures like bones in vitro. Moreover, new genomic resources from molluscs will be of interest to researchers in numerous fields.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190101338
Funder
Australian Research Council
Funding Amount
$373,711.00
Summary
Building your future: builder-building coevolution in animal architectures. This project aims to reconstruct how animal architectures change throughout time and how this affects body shapes and functions of their builders. By clarifying the biological role of building behaviour this project will assist in predicting long term responses of wildlife, ecosystems and human life to a changing environment. The project expects to be achieved by comparing the structure, assembly and mechanical performan ....Building your future: builder-building coevolution in animal architectures. This project aims to reconstruct how animal architectures change throughout time and how this affects body shapes and functions of their builders. By clarifying the biological role of building behaviour this project will assist in predicting long term responses of wildlife, ecosystems and human life to a changing environment. The project expects to be achieved by comparing the structure, assembly and mechanical performance of animal architectures with animal morphology and performance in a global phylogenetic framework. This is critical for strategic planning of wildlife and landscape management.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101567
Funder
Australian Research Council
Funding Amount
$374,848.00
Summary
Skulls as machines: diversity and evolution in a group of charismatic Australian lizards. This project uses sophisticated computer software to analyse how the complex skulls of dragon lizards work. This will provide a greater understanding of the factors underlying their evolution and radiation in Australia where they are one of the most successful lizard groups and a vital part of the desert fauna.
On the move: the study of self-organised movement of animal groups with and without leadership. This project will uncover the common principles that control the movement of large groups of organisms. We will focus on swarming honey bees, hopping bands of billions of locusts and millions of crickets marching in unison. The outcomes of our research will be broadly applicable to other collective phenomena, even to traffic and crowd control in humans.
Social insects as model systems in complexity science. Many optimisation algorithms are based on the behaviour of social insects. These algorithms function well under static conditions, when there is only one optimal solution. This project will determine how individual insect behaviour affects collective behaviour. Outcomes will allow the development of better algorithms.
Assessing gene function in the developing vertebrate brain using zebrafish as a model system. Although the vertebrate brain is the most complicated biological tissue it arises from a very simple sheet of cells during embryogenesis. Groups of nerve cells begin to communicate with each other through long interconnecting processes called axons. This project seeks to understand the role of specific genes in this process. This is the first time that the mechanisms controlling the growth of the ear ....Assessing gene function in the developing vertebrate brain using zebrafish as a model system. Although the vertebrate brain is the most complicated biological tissue it arises from a very simple sheet of cells during embryogenesis. Groups of nerve cells begin to communicate with each other through long interconnecting processes called axons. This project seeks to understand the role of specific genes in this process. This is the first time that the mechanisms controlling the growth of the earliest axons in the vertebrate brain will be examined in a living brain. Our analysis is expected to discover genes that are targets for manipulation of axon growth.Read moreRead less
The evolution of biological scaling. This project aims to understand why so few biological traits scale proportionally with body size. In contrast to previous mechanistic studies of this longstanding question, the problem will be approached from an evolutionary viewpoint, using artificial selection to engineer animals in which biological scaling laws are either broken or enhanced. By measuring the consequences of this for fitness, the project will provide a new understanding of how organismal si ....The evolution of biological scaling. This project aims to understand why so few biological traits scale proportionally with body size. In contrast to previous mechanistic studies of this longstanding question, the problem will be approached from an evolutionary viewpoint, using artificial selection to engineer animals in which biological scaling laws are either broken or enhanced. By measuring the consequences of this for fitness, the project will provide a new understanding of how organismal size and physiology evolve in nature. The approach should provide significant benefits to our understanding of the role of genetic constraints in hindering or facilitating biological adaptation, furthering our understanding of the capacity of animals to respond to environmental change.Read moreRead less
Vulnerability to cocaine use: discovering common mechanisms conserved across animal phyla. Drug abuse costs Australia an estimated $ 20 billion each year, and research is urgently needed to understand how drugs cause long-term behavioural dysfunction. Our research will identify the basal cellular mechanisms underlying drug abuse and addiction, which are likely to be the best targets for therapies to prevent and cure addiction. Our findings are also relevant to other neuropsychiatric disorders r ....Vulnerability to cocaine use: discovering common mechanisms conserved across animal phyla. Drug abuse costs Australia an estimated $ 20 billion each year, and research is urgently needed to understand how drugs cause long-term behavioural dysfunction. Our research will identify the basal cellular mechanisms underlying drug abuse and addiction, which are likely to be the best targets for therapies to prevent and cure addiction. Our findings are also relevant to other neuropsychiatric disorders related to drug abuse (e.g. depression, anxiety) that are on the increase in Australia. Our work will enhance Australia's reputation for neuroscience research, and will provide training for students in neuropharmacology and molecular neurobiology.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE180100949
Funder
Australian Research Council
Funding Amount
$365,058.00
Summary
Did colour vision evolve in the dark? This project aims to investigate the ability of fishes to perceive colour in dim-light conditions by studying representatives from two delicate and endangered ecosystems, coral reefs (nocturnal fish) and the deep-sea. Through a multidisciplinary approach to understanding colour vision and animal behaviour, this study expects to fill a knowledge gap in visual neuroscience and ecology while adding to the understanding of how marine creatures see and interact. ....Did colour vision evolve in the dark? This project aims to investigate the ability of fishes to perceive colour in dim-light conditions by studying representatives from two delicate and endangered ecosystems, coral reefs (nocturnal fish) and the deep-sea. Through a multidisciplinary approach to understanding colour vision and animal behaviour, this study expects to fill a knowledge gap in visual neuroscience and ecology while adding to the understanding of how marine creatures see and interact. This should provide benefits in conservation and management strategies and may also inspire the development of new sensor technologies.Read moreRead less