Dynamics and correlations of many-body systems. The proposed program will greatly enhance Australian science through linking innovative
theoretical techniques with the successful ongoing Australian experimental program in atom
lasers, atom chip interferometry and ultra-cold fermions. Pioneering theoretical methods in
quantum phase-space are internationally recognized, and will be extended into new areas relevant
to Australia. These have fundamental significance to fields ranging from nanotec ....Dynamics and correlations of many-body systems. The proposed program will greatly enhance Australian science through linking innovative
theoretical techniques with the successful ongoing Australian experimental program in atom
lasers, atom chip interferometry and ultra-cold fermions. Pioneering theoretical methods in
quantum phase-space are internationally recognized, and will be extended into new areas relevant
to Australia. These have fundamental significance to fields ranging from nanotechnology to
astrophysics, as well as providing a route to improved atomic clocks and other instruments.
Combining these theoretical and computational methods from the physical sciences with biology
and genetics will provide future cross-disciplinary benefits to Australian biomedical science.Read moreRead less
Uncovering the molecular mechanisms of potassium channel activity. The aim of this project is to determine the mechanisms of protein-mediated potassium ion transport across cell membranes. It will combine advanced simulations, structural biology and electrophysiology to describe the detailed molecular processes underscoring calcium-activated potassium channel conduction, gating and inactivation. The expected outcome is an improved description of how ion channels recognise and respond to physiolo ....Uncovering the molecular mechanisms of potassium channel activity. The aim of this project is to determine the mechanisms of protein-mediated potassium ion transport across cell membranes. It will combine advanced simulations, structural biology and electrophysiology to describe the detailed molecular processes underscoring calcium-activated potassium channel conduction, gating and inactivation. The expected outcome is an improved description of how ion channels recognise and respond to physiological stimuli to control electrical signalling the body. Our results will provide benefits in the form of basic understanding relevant to ion transport phenomena in biological systems, and atomic-level views of nervous system function to guide future directions in pharmacology.Read moreRead less
Decoherence in quantum computing and quantum electromechanical systems. Australia is one of the world leaders in fundamental studies and implementation of quantum computing and quantum electromechanical systems. By developing a framework to quantify and control noise due to decoherence in such systems, this research will facilitate progress in the development and understanding of quantum computing and quantum electromechanical devices. The project will also significantly strengthen the general r ....Decoherence in quantum computing and quantum electromechanical systems. Australia is one of the world leaders in fundamental studies and implementation of quantum computing and quantum electromechanical systems. By developing a framework to quantify and control noise due to decoherence in such systems, this research will facilitate progress in the development and understanding of quantum computing and quantum electromechanical devices. The project will also significantly strengthen the general representation of research on decoherence, a field of crucial importance to many areas of theoretical and experimental physics, in Australia. Funding of this project will enable Australia to further expand its leading position in cutting-edge science and next-generation technology.
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Ultracold atomic Fermi gases in the strongly interacting regime: A new frontier of quantum many-body physics. Ultra-cold atoms are one of the most rapidly developing areas in twenty-first century physics. The scientific importance of studying strongly interacting Fermi gases is indicated by the fact that five Nobel prizes in physics have been awarded in fields relevant to ultra-cold atoms in the last decade. Australia is now developing a reputation for world-class research in this new area, with ....Ultracold atomic Fermi gases in the strongly interacting regime: A new frontier of quantum many-body physics. Ultra-cold atoms are one of the most rapidly developing areas in twenty-first century physics. The scientific importance of studying strongly interacting Fermi gases is indicated by the fact that five Nobel prizes in physics have been awarded in fields relevant to ultra-cold atoms in the last decade. Australia is now developing a reputation for world-class research in this new area, with new cold-fermion experiments now underway in Melbourne. This project will build national and international cooperation in this field, provide world-class research training opportunities and advance Australia's leadership position. As well as improving scientific understanding, it has the potential to lead to new energy-saving technologies in future.Read moreRead less
Crossing quantum-classical boundaries in a single particle. This project is aimed at constructing and observing an individual quantum system that can exhibit chaotic behaviour under controllable conditions. It is a long-sought goal of modern physics that can become reality for the first time in the world, thanks to the unique availability in Australia of the most quantum-coherent single spin ever made and a long history of theoretical advances in the field. Turning a spin into a chaotic system w ....Crossing quantum-classical boundaries in a single particle. This project is aimed at constructing and observing an individual quantum system that can exhibit chaotic behaviour under controllable conditions. It is a long-sought goal of modern physics that can become reality for the first time in the world, thanks to the unique availability in Australia of the most quantum-coherent single spin ever made and a long history of theoretical advances in the field. Turning a spin into a chaotic system will uncover the true nature of the quantum-classical boundary, and verify whether an underlying classical chaotic dynamics ultimately influences the behaviour of quantum systems. It is expected that the discoveries made will illuminate the path towards the technological exploitation of increasingly complex quantum devices.Read moreRead less
Fundamental physics in distant galaxies. The fundamental constants of Nature are assumed to characterise physics in our entire Universe, but are they really the same everywhere and throughout its entire 14 billion year history? This project will answer this question with the first large-scale, purpose-built observational programme on one of the world's biggest and best telescopes.
Development of a neutral helium beam microscope. This project would demonstrate Australia's capability in developing leading edge technologies applicable to the growing nanotechnology industry. The development of a neutral helium beam microscope brings into Australia expertise in the emerging field of molecular optics, and would place Australia as one of the first countries to make a commitment to this field. The project will develop a prototype instrument which is aimed at becoming a commercial ....Development of a neutral helium beam microscope. This project would demonstrate Australia's capability in developing leading edge technologies applicable to the growing nanotechnology industry. The development of a neutral helium beam microscope brings into Australia expertise in the emerging field of molecular optics, and would place Australia as one of the first countries to make a commitment to this field. The project will develop a prototype instrument which is aimed at becoming a commercially viable product - the neutral helium beam microscope. The possibilities of using the microscope system as a nanofabrication device would also give researchers in Australia the ability to fabricate structures that could not be manufactured anywhere else in the world.Read moreRead less
SCP/TAPS proteins of the barber’s pole worm. This integrated, collaborative project, will explore, in a targeted way, the structure and function of a key group of molecules in a socio-economically important eukaryotic pathogen and their involvement in pathogen-host interactions. Fundamental knowledge and understanding of these molecules will provide a solid foundation for understanding disease processes and finding new intervention strategies for a range of pathogens. This is crucial, given the ....SCP/TAPS proteins of the barber’s pole worm. This integrated, collaborative project, will explore, in a targeted way, the structure and function of a key group of molecules in a socio-economically important eukaryotic pathogen and their involvement in pathogen-host interactions. Fundamental knowledge and understanding of these molecules will provide a solid foundation for understanding disease processes and finding new intervention strategies for a range of pathogens. This is crucial, given the serious drug resistance problems in pathogens, and residue problems in meat, milk and the environment.Read moreRead less
Cosmological vacuum stability as a window on fundamental physics. Vacuum is not just the absence of matter: it is the lowest-energy state of our Universe. This project aims to investigate the existence of new particles via their impacts upon the vacuum of the Universe. It expects to develop methods required to extract information on the existence of new particles from the vacuum, using transitions between different vacua, resulting gravitational waves, and results from a broad range of other co ....Cosmological vacuum stability as a window on fundamental physics. Vacuum is not just the absence of matter: it is the lowest-energy state of our Universe. This project aims to investigate the existence of new particles via their impacts upon the vacuum of the Universe. It expects to develop methods required to extract information on the existence of new particles from the vacuum, using transitions between different vacua, resulting gravitational waves, and results from a broad range of other complementary experiments. Expected outcomes include comprehensive tests of four of the most compelling theoretical frameworks for new particles. Significant expected benefits include advanced training for Australian students in numerical methods, software development, statistical analysis and research computing.Read moreRead less
Statistical methods for detection of non-coding RNAs in eukaryote genomes. Understanding how eukaryotic cells work is a major goal of 21st century biology. A crucial step will be to catalogue the functional components of eukaryotic genomes. Australian researchers must be involved in this process at an early stage, in order to maximise commercial opportunities, attract quality researchers and position ourselves for further advances. This project will make major contributions to international effo ....Statistical methods for detection of non-coding RNAs in eukaryote genomes. Understanding how eukaryotic cells work is a major goal of 21st century biology. A crucial step will be to catalogue the functional components of eukaryotic genomes. Australian researchers must be involved in this process at an early stage, in order to maximise commercial opportunities, attract quality researchers and position ourselves for further advances. This project will make major contributions to international efforts in this area, via the development of statistical methods for segmenting genomes, classification of those segments, and study of the resulting classes. In the long term, enhanced understanding of eukaryotic cells will lead to breakthroughs in biology, and to medical, pharmaceutical, agricultural and scientific advances.Read moreRead less