Individualised predictions of circadian timing, sleep, and performance. The body's 24-hour clock regulates when we feel sleepy or alert. In shift workers, disrupted sleep and rhythms leads to fatigue and costly, often deadly, workplace accidents. Existing methods for measuring body clock timing are costly, impractical for operational settings, and do not work in real time. Using a shift-worker population, this project will develop models that accurately predict body timing, sleep/wake patterns, ....Individualised predictions of circadian timing, sleep, and performance. The body's 24-hour clock regulates when we feel sleepy or alert. In shift workers, disrupted sleep and rhythms leads to fatigue and costly, often deadly, workplace accidents. Existing methods for measuring body clock timing are costly, impractical for operational settings, and do not work in real time. Using a shift-worker population, this project will develop models that accurately predict body timing, sleep/wake patterns, and performance for an individual, requiring only a simple activity/light sensor and an assessment of the body clock's sensitivity to light. The new model would revolutionise fatigue management and make safer work environments for millions of shift workers. Read moreRead less
The genetic basis of human memory. This project will examine the relationship between genetic variation and performance of normal individuals on a comprehensive range of memory test indicators. Results of the study will clarify the genetic basis of human memory and provide a better understanding of this important function.
Examining the relationship between error processing, cognitive control and emotion: a cognitive neuroscience approach. The proposed research aims to contribute to current scientific thinking on how the processing of errors influences self-monitoring and cognitive performance. The ability to monitor one's cognitive performance deteriorates with normal ageing, and is particularly affected in a range of clinical conditions, where it is a reliable predictor of a poor prognostic outcome. This project ....Examining the relationship between error processing, cognitive control and emotion: a cognitive neuroscience approach. The proposed research aims to contribute to current scientific thinking on how the processing of errors influences self-monitoring and cognitive performance. The ability to monitor one's cognitive performance deteriorates with normal ageing, and is particularly affected in a range of clinical conditions, where it is a reliable predictor of a poor prognostic outcome. This project aims to clarify understanding of the cognitive and neural processes underlying self-monitoring, as an important first step to improving rehabilitation and management methods for age-related impairments such as Alzheimer's disease, and prominent mental health conditions such as schizophrenia.Read moreRead less
Examining the neural mechanisms underlying cognitive control and its application to clinical syndromes featuring dyscontrol. This project will examine the cognitive control and its underlying neural mechanisms. Understanding this relationship is of major scientific interest because cognitive control dysfunction is related to a number of Australia's major social and economic problems, including drug dependence.
Discovery Early Career Researcher Award - Grant ID: DE240100327
Funder
Australian Research Council
Funding Amount
$440,970.00
Summary
Understanding how predictions modulate visual perception. The brain uses sensory predictions to help efficiently make sense of complex visual input. This project aims to explore how the brain generates, uses, and integrates different sources of predictive information to facilitate efficient visual perception. The outcomes are expected to be of both theoretical and practical benefit as they will help to refine influential theoretical models and generate findings with practical, real-world applic ....Understanding how predictions modulate visual perception. The brain uses sensory predictions to help efficiently make sense of complex visual input. This project aims to explore how the brain generates, uses, and integrates different sources of predictive information to facilitate efficient visual perception. The outcomes are expected to be of both theoretical and practical benefit as they will help to refine influential theoretical models and generate findings with practical, real-world applications in computer vision.Read moreRead less
Testing the ghost with the machine: Empirical investigations of cognition using high-field functional magnetic resonance imaging. The primary aim of the project is to test hypotheses about the cognitive architecture of word production and negative priming using high-field functional magnetic resonance imaging (fMRI). Additional aims/outcomes are to apply a novel fMRI acquisition sequence that permits overt verbal responding with rapid presentation of trials and collection of the time course of t ....Testing the ghost with the machine: Empirical investigations of cognition using high-field functional magnetic resonance imaging. The primary aim of the project is to test hypotheses about the cognitive architecture of word production and negative priming using high-field functional magnetic resonance imaging (fMRI). Additional aims/outcomes are to apply a novel fMRI acquisition sequence that permits overt verbal responding with rapid presentation of trials and collection of the time course of the blood oxygen level dependent (BOLD) signal, and to further develop a methodology that delineates the logic of making inferences about cognitive systems from functional neuroimaging data. These represent potentially significant developments in the fields of cognitive neuroscience and functional neuroimaging.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100120
Funder
Australian Research Council
Funding Amount
$374,973.00
Summary
How do we become aware of stimuli in our spatial environment? The brain constantly creates an awareness of the stimuli in our spatial environment but at the moment it is unclear how different brain regions integrate spatial and stimulus information. The aim of this project is to better understand this integration by using a combination of brain imaging and brain stimulation techniques.
CogChip: development of a targeted genotyping chip for executive function. This project aims to use DNA sequencing technology to identify the genetics of executive function. Our capacities to focus on a task at hand, to filter distractions and to inhibit unwanted impulses, are collectively referred to as executive functions. Executive function varies on a continuum in the general population across the lifespan, with individual differences largely due to differences in underlying genetics. The pr ....CogChip: development of a targeted genotyping chip for executive function. This project aims to use DNA sequencing technology to identify the genetics of executive function. Our capacities to focus on a task at hand, to filter distractions and to inhibit unwanted impulses, are collectively referred to as executive functions. Executive function varies on a continuum in the general population across the lifespan, with individual differences largely due to differences in underlying genetics. The project proposes to leverage this knowledge to develop a customised genotyping chip, which may find application for prediction of individual differences in executive ability across multiple settings including education and industry. Expected outcomes for the project will include breakthrough insights into the biology of cognition, and a genetic read-out of individual differences in executive ability, which could have broad application including the potential to facilitate the targeting of cognitive, educational or workplace training for those most at risk of adverse outcomes.Read moreRead less
Neurophysiological predictors of brain stimulation outcomes. This project aims to determine the cognitive and neurophysiological factors that predict an individual’s response to non-invasive brain stimulation used to target learning and executive function processes. Stimulation methods show immense promise for elucidating the causal neural substrates of cognition, and for enhancing performance in a range of applied settings. However, there are large individual differences in response to such int ....Neurophysiological predictors of brain stimulation outcomes. This project aims to determine the cognitive and neurophysiological factors that predict an individual’s response to non-invasive brain stimulation used to target learning and executive function processes. Stimulation methods show immense promise for elucidating the causal neural substrates of cognition, and for enhancing performance in a range of applied settings. However, there are large individual differences in response to such interventions. Using advanced imaging techniques, the project aims to provide comprehensive insights into the determinants of these individual differences. Outcomes and benefits include identifying brain characteristics that determine stimulation efficacy and informing the design of protocols for applied use.Read moreRead less
Neural substrates of paired decision-making training and brain stimulation. This project aims to provide definitive evidence on the efficacy of cognitive training, brain stimulation for enhancing performance, and will reveal the underlying neural processes involved. Outcomes and benefits include identifying the functional neural mechanisms and structural correlates of these effects for individuals and groups, informing cognitive training and stimulation approaches in a range of current settings, ....Neural substrates of paired decision-making training and brain stimulation. This project aims to provide definitive evidence on the efficacy of cognitive training, brain stimulation for enhancing performance, and will reveal the underlying neural processes involved. Outcomes and benefits include identifying the functional neural mechanisms and structural correlates of these effects for individuals and groups, informing cognitive training and stimulation approaches in a range of current settings, and a possible means of reducing the effects of age-related cognitive decline.Read moreRead less