Passive mechanical properties of human muscles. Australia has a strong record in the discipline of biomechanics. The proposed studies will help maintain Australia's standing in the discipline. They will provide fundamental new data on the properties of human muscles and basic insights into muscle growth and adaptation. The data will be used to develop more refined biomechanical models than is currently possible. The studies will also provide training in world-leading research methods for two PhD ....Passive mechanical properties of human muscles. Australia has a strong record in the discipline of biomechanics. The proposed studies will help maintain Australia's standing in the discipline. They will provide fundamental new data on the properties of human muscles and basic insights into muscle growth and adaptation. The data will be used to develop more refined biomechanical models than is currently possible. The studies will also provide training in world-leading research methods for two PhD students and a research associate.Read moreRead less
Measuring large deformation tissue mechanical behaviour in living humans. This project aims to develop new in vivo imaging methods to characterise the nonlinear mechanical behaviour of soft biological tissues, and use them to measure the properties of muscle, liver and adipose tissue in human subjects. Comprehensively characterising the mechanical properties of an individual person’s body tissues in vivo is a long-standing challenge in biomechanics and biomedical engineering. These new methods a ....Measuring large deformation tissue mechanical behaviour in living humans. This project aims to develop new in vivo imaging methods to characterise the nonlinear mechanical behaviour of soft biological tissues, and use them to measure the properties of muscle, liver and adipose tissue in human subjects. Comprehensively characterising the mechanical properties of an individual person’s body tissues in vivo is a long-standing challenge in biomechanics and biomedical engineering. These new methods aim to overcome major imitations of current biomechanical imaging methods, and make new measurements of the nonlinear mechanical properties of muscle, liver and adipose tissues. These techniques may be useful for future diagnostic, biomechanics and mechanobiology applications.Read moreRead less
Protecting Occupants in Vehicle Rollover Crashes. This project addresses a public health issue involving rollover crashes. It will help prevent 340 deaths, 6000 injuries and save $3.6 billion annually in Australia and many fold this number internationally. A dynamic rollover crashworthiness test protocol, that ensures efficient and economical vehicle rollover protection systems are designed and manufactured, will be provided to consumer and regulatory bodies to consider and implement. In additio ....Protecting Occupants in Vehicle Rollover Crashes. This project addresses a public health issue involving rollover crashes. It will help prevent 340 deaths, 6000 injuries and save $3.6 billion annually in Australia and many fold this number internationally. A dynamic rollover crashworthiness test protocol, that ensures efficient and economical vehicle rollover protection systems are designed and manufactured, will be provided to consumer and regulatory bodies to consider and implement. In addition, much needed Occupational Health & Safety information regarding vehicle rollover crashworthiness, which provide a safe work place environment for professional drivers and employees using vehicles, will be supplied to industry fleet managers, defence and emergency services.Read moreRead less
How do mechanics, neural drive and muscle architecture interact in muscles? This project will determine how an individual person’s muscle activity, muscle structure and mechanical properties, and the local mechanical conditions around the muscle interact as muscles move and deform, by using experiments and personalised computational models that can examine these factors and their interactions concurrently. To achieve this, we will develop novel magnetic resonance imaging methods to measure the m ....How do mechanics, neural drive and muscle architecture interact in muscles? This project will determine how an individual person’s muscle activity, muscle structure and mechanical properties, and the local mechanical conditions around the muscle interact as muscles move and deform, by using experiments and personalised computational models that can examine these factors and their interactions concurrently. To achieve this, we will develop novel magnetic resonance imaging methods to measure the mechanical properties of muscles in humans and methods for modelling muscles. As well as answering fundamental scientific questions about muscle function, these new techniques will provide a platform for studying other muscles, and for future development of muscle training methods and technologies to optimise muscle function.Read moreRead less
Rheological and Electrical Properties of Biological Soft Tissues. Research on coupling rheological and electrical properties of biological soft tissues and their composites is fundamental to medical and sport sciences, as well as the optimal design and management of smart biomedical devices and bio-microtransducers. This project aims to develop an effective rheological and electrical constitutive law and finite element implementation together with supporting experiments to reveal the novel coupl ....Rheological and Electrical Properties of Biological Soft Tissues. Research on coupling rheological and electrical properties of biological soft tissues and their composites is fundamental to medical and sport sciences, as well as the optimal design and management of smart biomedical devices and bio-microtransducers. This project aims to develop an effective rheological and electrical constitutive law and finite element implementation together with supporting experiments to reveal the novel coupling behaviour of viscoelastic and electric fields of the innovative smart biological soft tissue. These results will provide a guideline for future research in tissue engineering and help Australian biomedical science and industries improve the modern biotransducers and smart biomicro-devices.Read moreRead less
Computational Scaffold Optimisation for Tissue Engineering. Due to exceptional potential, tissue engineering has attracted over US$4.5 billion research and development investment and another US$2.6 billion market capital since 1990. It is important to cement Australia's position in such a highly competitive field. This project aims to develop a novel technology for scaffold-based tissue engineering, which would help Australia lead in the relevant area and increase its competitiveness in the futu ....Computational Scaffold Optimisation for Tissue Engineering. Due to exceptional potential, tissue engineering has attracted over US$4.5 billion research and development investment and another US$2.6 billion market capital since 1990. It is important to cement Australia's position in such a highly competitive field. This project aims to develop a novel technology for scaffold-based tissue engineering, which would help Australia lead in the relevant area and increase its competitiveness in the future global market of biomaterials, tissue products, biomedical software and instruments. An enormous socio-economic benefit to Australia would be a significant improvement in the clinical success rate for our ageing population. Read moreRead less
Nonlinear viscoelastic properties of paediatric soft tissues throughout development. This project will determine how the soft tissues of the human body change during normal development, and how these changes affect their response to mechanical forces. This data will be useful for understanding childhood injury mechanisms, and how diseases affect children's soft tissues.
Taking risks with safety gear: Biomechanical and psychological perspectives on risk compensation. This project uniquely combines objective and subjective measures in investigating whether and how people take more risks in the face of safety interventions. Investigating changes in behaviour with safety gear in sport is of benefit because it (a) allows comprehensive measurement of risk-taking behaviour and (b) can result in significant health benefits. These health benefits include reducing sports ....Taking risks with safety gear: Biomechanical and psychological perspectives on risk compensation. This project uniquely combines objective and subjective measures in investigating whether and how people take more risks in the face of safety interventions. Investigating changes in behaviour with safety gear in sport is of benefit because it (a) allows comprehensive measurement of risk-taking behaviour and (b) can result in significant health benefits. These health benefits include reducing sports injuries through improving the efficacy of safety gear, and applications to risk-taking in other health domains, such as patient safety, occupational safety, and transport safety. Through improved methodology, the project should advance international research practice on this controversial topic.Read moreRead less