Building a Smart Diagnostic System for Low Back Ailments. This research will develop an early back ailment diagnostic system that will reduce the recurrence of low back pain, and hence reduce the cost to the health system. This is significant to the community from prevention of pain, to the health care system that spends billions of dollars combating this modern day ailment and towards the industry where the low back pain is the single largest reason for sick leave in Australia. It will also giv ....Building a Smart Diagnostic System for Low Back Ailments. This research will develop an early back ailment diagnostic system that will reduce the recurrence of low back pain, and hence reduce the cost to the health system. This is significant to the community from prevention of pain, to the health care system that spends billions of dollars combating this modern day ailment and towards the industry where the low back pain is the single largest reason for sick leave in Australia. It will also give rise to employment of skilled technical people and an opportunity to increase high-value exports from Australia.Read moreRead less
Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide f ....Novel Self Assembled Particle Systems as a Key to Next Generation Biosensor Technology. Development and commercialisation of products utilising nanotechnology is crucial to future wealth creation for Australia. The translational research in this proposal will progress innovative concepts in nanotechnology-based biosensors, with potential for substantial improvements in disease diagnosis, leading to more economical and timely therapy. The products that arise from this research will also provide further employment for Australians, building on Universal Biosensor’s proven record of commercialization in Australia. The project will lead to training of Australian researchers in nanotechnology and in utilization of key Australian science infrastructure including the Australian Synchrotron and the Melbourne Centre for Nanofabrication.Read moreRead less
Special Research Initiatives - Grant ID: SR0354583
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Biodevice fabrication through intelligent surface modification. Achieving the reliable control of the attachment of proteins and other macromolecules to surfaces needed for sophisticated biosensors and medical diagnostics requires expertise and infrastructure from a diverse range of disciplines from the physical, chemical and biological sciences and engineering. This network will bring together researchers from a multidisciplinary pool working on problems relevant to the creation of functional s ....Biodevice fabrication through intelligent surface modification. Achieving the reliable control of the attachment of proteins and other macromolecules to surfaces needed for sophisticated biosensors and medical diagnostics requires expertise and infrastructure from a diverse range of disciplines from the physical, chemical and biological sciences and engineering. This network will bring together researchers from a multidisciplinary pool working on problems relevant to the creation of functional surfaces for applications in biodevices. The program we envisage will break down the barriers imposed by disciplinary boundaries and technical terminology to bring together the skills and infrastructure required to make rapid advances in this field.Read moreRead less
Functional nonlinear optical endoscopy - the third-generation optical endoscopy technology toward early cancer detection at a cellular level. The third-generation optical endoscopy technology can be used for a better understanding of nonlinear optical interaction with organ sites and thus for early cancer detection. Such a novel device will enable biomedical scientists to gain the fundamental knowledge needed to enable Australians to develop better medical strategies for health and productive li ....Functional nonlinear optical endoscopy - the third-generation optical endoscopy technology toward early cancer detection at a cellular level. The third-generation optical endoscopy technology can be used for a better understanding of nonlinear optical interaction with organ sites and thus for early cancer detection. Such a novel device will enable biomedical scientists to gain the fundamental knowledge needed to enable Australians to develop better medical strategies for health and productive lives. Since 1 in 3 Australians will feel the effects of cancers, development of portable nonlinear optical endoscopes is of national importance, in particular for rural Australia, and therefore improves the healthcare of human beings. The potential spin-off activity will lead to economic benefits from new R&D development.Read moreRead less
Development of Novel Two-dimensional Techniques for Magnetic Resonance In-vivo Spectroscopy. Body chemistry alters with functionality, pain, ageing and disease. These changes can be recorded by magnetic resonance (MR) spectroscopy (MRS) in vivo in a whole body MR scanner. When changes in chemistry can be recorded rapidly, and the individual species assigned, it will be possible to make a definitive diagnosis and in some cases allow the tailoring of treatment on an individual basis. This is curre ....Development of Novel Two-dimensional Techniques for Magnetic Resonance In-vivo Spectroscopy. Body chemistry alters with functionality, pain, ageing and disease. These changes can be recorded by magnetic resonance (MR) spectroscopy (MRS) in vivo in a whole body MR scanner. When changes in chemistry can be recorded rapidly, and the individual species assigned, it will be possible to make a definitive diagnosis and in some cases allow the tailoring of treatment on an individual basis. This is currently hampered by our inability to separate the composite resonances in a one dimensional MR spectrum. Research will allow two dimensional MRS to be implemented and provide detailed chemical information on human organs in vivo. Read moreRead less
Determination of lung morphology from X-ray phase contrast radiographs. Current methods of imaging the lung rely heavily on low contrast images obtained with chest radiography or computed tomography. This research will develop new X-ray phase contrast imaging techniques capable of providing a tenfold contrast increase over conventional chest radiography at a fraction of the X-ray dose of computed tomography. Methods of extracting quantitative information on lung morphology and pathology from pha ....Determination of lung morphology from X-ray phase contrast radiographs. Current methods of imaging the lung rely heavily on low contrast images obtained with chest radiography or computed tomography. This research will develop new X-ray phase contrast imaging techniques capable of providing a tenfold contrast increase over conventional chest radiography at a fraction of the X-ray dose of computed tomography. Methods of extracting quantitative information on lung morphology and pathology from phase contrast chest radiographs will be developed during this research. Eventual outcomes are likely to lead to improved methods of detecting lung disease and injury for both biomedical and clinical studies.Read moreRead less