Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or t ....Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or the acute exacerbation of existing disease. The impact of these new technologies on the early diagnosis and improved triaging of patients in emergency departments is potentially profound and could result in improved healthcare outcomes for the patients and reduced admissions to hospital as well as the development of a substantial international market.Read moreRead less
Creating new methods to study structure vision. The majority of the structure within natural images is due to third to fifth order correlations between image points. Research has shown that sensitivity to this higher order structure, provides so called Structure Vision. Research has also shown that as few as three to four brain mechanisms are involved, and these may be related to the Minkowski functionals, which in turn are related to the structural and surface properties of real materials. This ....Creating new methods to study structure vision. The majority of the structure within natural images is due to third to fifth order correlations between image points. Research has shown that sensitivity to this higher order structure, provides so called Structure Vision. Research has also shown that as few as three to four brain mechanisms are involved, and these may be related to the Minkowski functionals, which in turn are related to the structural and surface properties of real materials. This project aims to build on recent discoveries of new stimuli to implement objective tests with which to study structure vision with the Partner Organisation. The project aims to also expand on realistic models of how Structure Vision may be computed by just a few coupled cortical pyramidal cells.Read moreRead less
Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplin ....Development and characterization of a technology platform to study the mechanisms of scaffold/Bone Morphogenic Proteins (BMP) augmented large segmental bone healing. This project will increase understanding of bone engineering and in doing so will lead to superior treatments for bone defects. Such a treatment would be valuable in addressing the ever-increasing problems of diminished productivity and reduced quality of life associated with bone disorders as the population ages. The multidisciplinary and international team will be valuable in establishing Australia's prominence in this field and training the next generation of young scientists and engineers. The technologies developed will be of great interest to a large number of research groups and companies worldwide and will assist with fostering international collaboration and placing Australia at the forefront of this emerging field.Read moreRead less
Pedal and motor cycle helmet performance study. Cycling is a form of recreation and transport. Both pedal and motor cyclists are exposed to risks of head and neck injury. These injuries occur in young people and can have substantial health and economic impacts on the individuals and society. It is believed that injury rates can be reduced and an active lifestyle encouraged by improving helmet performance and understanding factors that lead to non-use. As helmet use is mandatory it is importa ....Pedal and motor cycle helmet performance study. Cycling is a form of recreation and transport. Both pedal and motor cyclists are exposed to risks of head and neck injury. These injuries occur in young people and can have substantial health and economic impacts on the individuals and society. It is believed that injury rates can be reduced and an active lifestyle encouraged by improving helmet performance and understanding factors that lead to non-use. As helmet use is mandatory it is important that Australians are provided with optimal helmets. The specification of product standards is also relevant for international trade agreements. Read moreRead less
Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology ....Noise-free Cryogenic Wavefront Sensing. This project aims to optimise the prototype adaptive optics technology for the Giant Magellan Telescope (GMT) by leveraging past investment in adaptive optics instrumentation and shortwave infrared detector systems. This project expects to generate significant improvements in GMT performance, with ten times greater image resolution than the Hubble Space Telescope and current estimates of >90% sky coverage, compared with ~50% coverage for current technology. Expected outcomes of this project include the development of a highly trained workforce and continued international collaboration in the field of high-technology sensor systems. This contribution to the GMT will provide significant benefits—it will change the way we view the Universe.Read moreRead less
A Laser Guide Star using a High Power, Synchronously Pumped Optical Parametric Oscillators. We will develop a novel high power source of 589nm coherent (laser) light to be used to create a laser guide star by exciting sodium atoms in the earth's upper atmosphere (the mesosphere). This is needed to determine the distortion caused by the atmosphere on an optical beam propagating through it and generate the information needed to correct those distortions using an adaptive optics telescope. This pr ....A Laser Guide Star using a High Power, Synchronously Pumped Optical Parametric Oscillators. We will develop a novel high power source of 589nm coherent (laser) light to be used to create a laser guide star by exciting sodium atoms in the earth's upper atmosphere (the mesosphere). This is needed to determine the distortion caused by the atmosphere on an optical beam propagating through it and generate the information needed to correct those distortions using an adaptive optics telescope. This project focuses on the development of a novel high power 589nm source based on a synchronously pumped optical parametric oscillator.Read moreRead less
Technologies for advanced optical fibre sensors. This project is to create a significantly better technology for exploration of oil and gas reserves under the ocean. Based on lasers and fibre optics, it leverages Australia's prodigious photonics expertise and couples it with Australia's established and well-regarded resource industry. Successful completion will enable better utilization of this country's natural resources, in particular oil and gas reserves, whilst also creating a high technolog ....Technologies for advanced optical fibre sensors. This project is to create a significantly better technology for exploration of oil and gas reserves under the ocean. Based on lasers and fibre optics, it leverages Australia's prodigious photonics expertise and couples it with Australia's established and well-regarded resource industry. Successful completion will enable better utilization of this country's natural resources, in particular oil and gas reserves, whilst also creating a high technology export, given the size of the world marine survey market (US$4 billion). Better energy exploration technologies are vital to Australia and, indeed the world, as energy supply dwindles and the increased energy costs begin to impact negatively on economic growth.Read moreRead less
Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
Short-pulse laser cleaning for Australian heritage conservation. Conserving heritage objects is a demanding discipline, requiring a suite of techniques for different problems. Overseas, laser cleaning using long pulse techniques leaves microscopic damage as discrete chunks of material are removed, and is unsuitable for many materials. We have developed a short pulse laser process which can remove material molecule-by-molecule in a controlled fashion, and which can be readily halted once the fi ....Short-pulse laser cleaning for Australian heritage conservation. Conserving heritage objects is a demanding discipline, requiring a suite of techniques for different problems. Overseas, laser cleaning using long pulse techniques leaves microscopic damage as discrete chunks of material are removed, and is unsuitable for many materials. We have developed a short pulse laser process which can remove material molecule-by-molecule in a controlled fashion, and which can be readily halted once the final finish is achieved. We will research this technique for application to unique Australian heritage materials that are important to the specific conservation needs of the Australian War Memorial, the RAAF, Navy and Army Museums, Artlab Australia, and the Art Gallery of NSW.Read moreRead less
Pre-blast screening of improvised explosive devices - a National counter-terrorism initiative. The proposed research is focused on the specific needs of Australian counter-terrorism interests, including those of border protection, the customs service, transport authorities, forensic laboratories, etc. The support of this proposal will ensure that Australia, and its States and Territories are protected against terrorist threats. The support provided by the collaborating organisations from the var ....Pre-blast screening of improvised explosive devices - a National counter-terrorism initiative. The proposed research is focused on the specific needs of Australian counter-terrorism interests, including those of border protection, the customs service, transport authorities, forensic laboratories, etc. The support of this proposal will ensure that Australia, and its States and Territories are protected against terrorist threats. The support provided by the collaborating organisations from the various Federal and State police and forensic agencies, and the customs service, etc, highlights the importance of this project to the nation. Finally, a PhD student and a research assistant will be involved with the project and will gain specialised skills positioning them to make strong contributions to Australia's counter-terrorism measures.Read moreRead less