Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or t ....Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or the acute exacerbation of existing disease. The impact of these new technologies on the early diagnosis and improved triaging of patients in emergency departments is potentially profound and could result in improved healthcare outcomes for the patients and reduced admissions to hospital as well as the development of a substantial international market.Read moreRead less
A multiplex microscope platform to define molecular events in fluid systems. This project aims to develop a novel microscopy platform that will enable the visualisation and quantification of molecular events occurring under fluid shear stress. The project will generate new knowledge in platelet biology that will allow characterisation and prediction of key molecular and morphological changes occurring across a blood thrombus under flowing conditions as found in the blood vessels. These new tools ....A multiplex microscope platform to define molecular events in fluid systems. This project aims to develop a novel microscopy platform that will enable the visualisation and quantification of molecular events occurring under fluid shear stress. The project will generate new knowledge in platelet biology that will allow characterisation and prediction of key molecular and morphological changes occurring across a blood thrombus under flowing conditions as found in the blood vessels. These new tools and the imaging platform will have applications for researchers wishing to visualise small and rapid molecular events in four dimensions (length, width, height and across time) under fluid shear stress, which is applicable across a range of industries. The project expects to deliver the next generation of intravital microscopes that can visualise and quantify events in a challenging flow environment.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560716
Funder
Australian Research Council
Funding Amount
$864,610.00
Summary
A National T-ray Facility. T-rays are between microwaves and infrared on the electromagnetic spectrum. Recently, advances in femtosecond lasers enabled access to T-ray frequencies, producing an important new imaging modality for non-invasive sensing of materials and structures. Internationally, T-rays represent a rich new science leading to advanced forms of biophotonics, biomedical imaging and spectroscopy. Non-invasive T-ray diagnostics of nano- and bio-materials are being hotly pursued. The o ....A National T-ray Facility. T-rays are between microwaves and infrared on the electromagnetic spectrum. Recently, advances in femtosecond lasers enabled access to T-ray frequencies, producing an important new imaging modality for non-invasive sensing of materials and structures. Internationally, T-rays represent a rich new science leading to advanced forms of biophotonics, biomedical imaging and spectroscopy. Non-invasive T-ray diagnostics of nano- and bio-materials are being hotly pursued. The outcome will be a strategically important Australian T-ray facility that will provide immediate and transparent nationwide access. Historically, industry is transformed every time a new part of the electromagnetic spectrum becomes accessible - T-rays are the next frontier.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100164
Funder
Australian Research Council
Funding Amount
$500,000.00
Summary
GNOSIS: a new window on the early universe using revolutionary photonic technology. Australian astronomers have a long history in innovative instrumentation and are some of the early pioneers in infrared astronomy. The GNOSIS project brings together leading Australian astronomers to build on past success. This facility instrument makes use of recent technological advances in photonics—a key strength of Australian research and industry—to provide a dramatic improvement in observational sensitivit ....GNOSIS: a new window on the early universe using revolutionary photonic technology. Australian astronomers have a long history in innovative instrumentation and are some of the early pioneers in infrared astronomy. The GNOSIS project brings together leading Australian astronomers to build on past success. This facility instrument makes use of recent technological advances in photonics—a key strength of Australian research and industry—to provide a dramatic improvement in observational sensitivity at these wavelengths. This will allow Australian astronomers to carry out new science programmes that have not been possible to date. These programmes include unprecedented observations of very cool low mass stars, the first chemical information on dust-embedded star clusters, and accurate ages for distant galaxies.Read moreRead less
ARC Centre of Excellence for Integrative Brain Function. The Centre of Excellence for Integrative Brain Function will address one of the greatest scientific challenges of the 21st century to understand how the brain works. We will investigate complex functions such as attention, prediction and decision-making, which require the coordination of information processing by many areas of the brain. This will require a highly collaborative approach involving neurobiologists, cognitive scientists, eng ....ARC Centre of Excellence for Integrative Brain Function. The Centre of Excellence for Integrative Brain Function will address one of the greatest scientific challenges of the 21st century to understand how the brain works. We will investigate complex functions such as attention, prediction and decision-making, which require the coordination of information processing by many areas of the brain. This will require a highly collaborative approach involving neurobiologists, cognitive scientists, engineers and physicists, allowing us to translate our discoveries into novel technologies for the social and economic benefit of all Australians. We will also train a new generation of multidisciplinary researchers, and contribute our expertise to a range of public education and awareness programs.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0236657
Funder
Australian Research Council
Funding Amount
$210,000.00
Summary
Renewed Great Melbourne Telescope: Opening a Window on the Universe. We propose to refurbish the Great Melbourne Telescope (GMT) located at Mount Stromlo Observatory with a new state-of-the-art imager. This instrument will be available to the entire Australian Astronomical community, and will allow Australian researchers to undertake cutting edge research with this world leading two colour wide field imager. A fully automated observing and data reduction pipeline, a world first for a telescope o ....Renewed Great Melbourne Telescope: Opening a Window on the Universe. We propose to refurbish the Great Melbourne Telescope (GMT) located at Mount Stromlo Observatory with a new state-of-the-art imager. This instrument will be available to the entire Australian Astronomical community, and will allow Australian researchers to undertake cutting edge research with this world leading two colour wide field imager. A fully automated observing and data reduction pipeline, a world first for a telescope of this size, means astronomers can work on their data, analyzing everything from the Solar System, to the most distant objects in the Universe, rather than spending night after night at the telescope.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0882778
Funder
Australian Research Council
Funding Amount
$201,224.00
Summary
Water vapour radiometers for millimetre-wave phase correction for the Australia Telescope. Australia has a tradition of excellence in astronomy. Inspired by wonder about the cosmos, it stimulates public interest in science, so leading to the training of highly skilled graduates. In turn, this drives the development of technologies needed to pursue the science. The nation has invested in the technology for millimetre-wave astronomy, building the first interferometer in our hemisphere. This equipm ....Water vapour radiometers for millimetre-wave phase correction for the Australia Telescope. Australia has a tradition of excellence in astronomy. Inspired by wonder about the cosmos, it stimulates public interest in science, so leading to the training of highly skilled graduates. In turn, this drives the development of technologies needed to pursue the science. The nation has invested in the technology for millimetre-wave astronomy, building the first interferometer in our hemisphere. This equipment will capitalise on this investment, extending the capabilities of the Australia Telescope to maintain it as a front line instrument, attracting the best scientists here to use it. This will help nurture a vigorous radio-science community, one able to actively participate in the billion-dollar investment being made internationally in the field.Read moreRead less