Development of an implantable blood flow and pressure monitor for pulmonary hypertension. The aim is to develop an implantable device for continuous measurement of blood pressure and flow rate in the pulmonary artery. The device is to store data and download it on request to an external device. Development steps include design of the sensor lead incorporating impedance electrodes and a pressure transducer, numerical modelling of the electrode system, characterising pressure and flow waveforms f ....Development of an implantable blood flow and pressure monitor for pulmonary hypertension. The aim is to develop an implantable device for continuous measurement of blood pressure and flow rate in the pulmonary artery. The device is to store data and download it on request to an external device. Development steps include design of the sensor lead incorporating impedance electrodes and a pressure transducer, numerical modelling of the electrode system, characterising pressure and flow waveforms for condensed storage, establishing flow sensor and blood flow relationships and assessment of sensor stability and calibration demands. The device will facilitate research in pulmonary hypertension and may lead to clinical devices for monitoring effectiveness of treatment.Read moreRead less
New separation technologies for profiling metabolites in biological samples. Metabolomics is an important new field of science that is contributing to the understanding of life processes at the molecular level. But a widely acknowledged major limitation of current metabolomics technologies is the inability to accurately identify high numbers of detected metabolites in the biological extracts being studied. This project will develop cutting-edge separation science approaches to address this exist ....New separation technologies for profiling metabolites in biological samples. Metabolomics is an important new field of science that is contributing to the understanding of life processes at the molecular level. But a widely acknowledged major limitation of current metabolomics technologies is the inability to accurately identify high numbers of detected metabolites in the biological extracts being studied. This project will develop cutting-edge separation science approaches to address this existing problem in metabolomics analysis. In doing so it will provide enormous benefit to Australian biotechnology and biomedical research and play a major role in transferring capabilities to laboratories and research institutes that are involved in research aimed at elucidating biological pathways and networks.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100006
Funder
Australian Research Council
Funding Amount
$600,000.00
Summary
An adaptable and dedicated linear accelerator for medical radiation research. Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using this highly adaptable linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected.
Radio Interferometer Studies of Compact Astronomical Sources. The giant black holes in the centres of distant galaxies that are the topic of this study are used to set the reference frame for geodesy on the earth. Remote and exotic as they are, they have real-world applications such as improving the positions available from GPS receivers and measuring continental drift. The signal processing equipment being developed for this new telescope is based on FPGA (field programmable gate array) chips ....Radio Interferometer Studies of Compact Astronomical Sources. The giant black holes in the centres of distant galaxies that are the topic of this study are used to set the reference frame for geodesy on the earth. Remote and exotic as they are, they have real-world applications such as improving the positions available from GPS receivers and measuring continental drift. The signal processing equipment being developed for this new telescope is based on FPGA (field programmable gate array) chips, that promise to revolutionize the data processing industry, from radar to cellular telephones to computer networks. The young scientists who are working on this project will go on to lead the commercial and industrial applications of this new technology.Read moreRead less
Novel approach to study mechanisms of Na+ transport in plants using Lab on a Chip technology. A Lab on a Chip for sodium ion measurements in plants is proposed, offering a long overdue solution to the lack of appropriate techniques to study the mechanisms of sodium iron uptake, transport and compartmentation. Sodium ion transport is a key determinant of salt tolerance, but a good understanding of its transport mechanisms is lacking since no appropriate measurement tools are available. Using the ....Novel approach to study mechanisms of Na+ transport in plants using Lab on a Chip technology. A Lab on a Chip for sodium ion measurements in plants is proposed, offering a long overdue solution to the lack of appropriate techniques to study the mechanisms of sodium iron uptake, transport and compartmentation. Sodium ion transport is a key determinant of salt tolerance, but a good understanding of its transport mechanisms is lacking since no appropriate measurement tools are available. Using the system proposed here, sodium ion is separated from interfering ions, allowing fast and selective measurements. A series of ground breaking studies towards sodium ion uptake, transport and compartmentation in plants will be conducted using this Lab on a Chip.Read moreRead less
ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas ....ARC Centre of Excellence - Australian Centre for Electromaterials Science. The Centre will tackle some of the biggest challenges facing society: those of renewable energy, sustainable industries and enhancing human health. Improvements in all these areas are possible by developing electromaterials with improved efficiency in the generation and transfer of electrical charge. By developing new nano-materials and new theories to explain their behaviour, the Centre will make advances in the areas of human health through the regeneration of damaged nerves (eg. in spinal injury) and development of artificial muscles; in renewable energy (plastic solar cells, lightweight batteries and electronic textiles) and in sustainable industries (recovery of precious metals and new corrosion protection technologies).Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560868
Funder
Australian Research Council
Funding Amount
$552,475.00
Summary
SHRIMP SI - Microscale stable-isotope analysis in the Earth Sciences. Stable-isotope variations of elements such as oxygen, carbon, and sulphur, preserve the most profound records of environmental conditions during the geological, biological, and climatic evolution of Earth and planets. We will build a stable isotope ion microprobe (SHRIMP SI) to examine extraterrestrial and terrestrial systems in unprecedented detail. In terrestrial applications, the main issue is accuracy at the 0.01 percent ....SHRIMP SI - Microscale stable-isotope analysis in the Earth Sciences. Stable-isotope variations of elements such as oxygen, carbon, and sulphur, preserve the most profound records of environmental conditions during the geological, biological, and climatic evolution of Earth and planets. We will build a stable isotope ion microprobe (SHRIMP SI) to examine extraterrestrial and terrestrial systems in unprecedented detail. In terrestrial applications, the main issue is accuracy at the 0.01 percent level for 20-micron spots, which we can apply to studies of development of life on Earth, climatic records, weathering, and formation of ore bodies. Sample return missions of solar wind and comets will provide unique samples related to the formation of our solar system.Read moreRead less
Non-discriminatory, universal and sensitive detection technologies for fluid based separation techniques in the pharmaceutical industry. The proposed research is focused on the specific needs of Australian and global pharmaceutical industries, and addresses a problem which is becoming increasingly significant with new classes of pharmaceuticals. Successful achievement of the goals of the project will result in major savings of cost and time during drug development and will lead to the productio ....Non-discriminatory, universal and sensitive detection technologies for fluid based separation techniques in the pharmaceutical industry. The proposed research is focused on the specific needs of Australian and global pharmaceutical industries, and addresses a problem which is becoming increasingly significant with new classes of pharmaceuticals. Successful achievement of the goals of the project will result in major savings of cost and time during drug development and will lead to the production of safer drugs. The project will expand collaboration between Australia researchers and the world's largest pharmaceutical company. Specialised training will be provided to both postdoctoral and postgraduate researchers, positioning them to make strong contributions to Australia's growing pharmaceutical industry.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100094
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
The Mopra Radio Telescope. The Mopra Radio Telescope:
This project aims to use Australia’s Mopra Radio Telescope – the largest millimetre-wave dish in the southern hemisphere – to complete a survey of the distribution of molecular gas across the southern Milky Way. The millimetre-wavelength sky holds the key for understanding molecular clouds in which stars are born, and the Mopra Telescope is the world’s most capable facility for imaging these clouds. The expected outcome is an order of magnit ....The Mopra Radio Telescope. The Mopra Radio Telescope:
This project aims to use Australia’s Mopra Radio Telescope – the largest millimetre-wave dish in the southern hemisphere – to complete a survey of the distribution of molecular gas across the southern Milky Way. The millimetre-wavelength sky holds the key for understanding molecular clouds in which stars are born, and the Mopra Telescope is the world’s most capable facility for imaging these clouds. The expected outcome is an order of magnitude improvement in the clarity of our view of this central component of the Galaxy. The project also aims to enable Mopra to serve as a key element in the Australian Long Baseline Array. The project aims to ensure Australian involvement in three grand design international endeavours.Read moreRead less
Disposable microdevices for fast ion analysis. The design and fabrication of a microdevice for ion chromatography will introduce Australia to the field of miniaturised total analytical systems (µTAS). The availability of infrastructure, technology and experience in the µTAS area will provide the foundation for specialised commercialisation of sophisticated, chip-based analytical instruments. These instruments have important applications in forensic, clinical and environmental chemistry.