Special Research Initiatives - Grant ID: SR0354734
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving h ....The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving health care and reducing health care costs. To be successful, a device must include all relevant disciplines in the research, development and testing phases. This network will bring together these groups, promoting knowledge sharing and cross-disciplinary investigations that illuminate current device limitations and potential solutions.Read moreRead less
Dielectric contrast imaging for 7 Tesla magnetic resonance applications. This project aims to develop novel radio-frequency (RF) technology, ensuring that the benefits of high-field magnetic resonance imaging (MRI) are available for a broader range of applications. This project will develop a new contrast mechanism directly related to the RF properties of individual tissue types, circumventing a limitation of intensity based imaging. This technology will enhance Australia’s global impact the dev ....Dielectric contrast imaging for 7 Tesla magnetic resonance applications. This project aims to develop novel radio-frequency (RF) technology, ensuring that the benefits of high-field magnetic resonance imaging (MRI) are available for a broader range of applications. This project will develop a new contrast mechanism directly related to the RF properties of individual tissue types, circumventing a limitation of intensity based imaging. This technology will enhance Australia’s global impact the development of imaging technology for healthcare, biomedical research and advanced diagnostics.Read moreRead less
Advanced Magnetic Resonance Imaging at 7 Tesla: Resolving the fundamental radiofrequency field-tissue interaction problem at ultra-high field. Ultra-high-field Magnetic Resonance Imaging (MRI) systems offer the potential for faster, more accurate diagnostic imaging. However, current applications are limited by the fundamental challenge of strong interactions between the electromagnetic field and human tissues, which result in poor image quality and/or compromised patient safety. Using a novel, s ....Advanced Magnetic Resonance Imaging at 7 Tesla: Resolving the fundamental radiofrequency field-tissue interaction problem at ultra-high field. Ultra-high-field Magnetic Resonance Imaging (MRI) systems offer the potential for faster, more accurate diagnostic imaging. However, current applications are limited by the fundamental challenge of strong interactions between the electromagnetic field and human tissues, which result in poor image quality and/or compromised patient safety. Using a novel, subject-specific imaging approach, this research will design and develop an ultra-high-field radiofrequency technology capable of offering high-performance imaging without jeopardising patient safety. This research will lay the groundwork for the translation of ultra-high field MRI research into clinical practice, generating new capabilities for diagnostic technologies.Read moreRead less
Real-time cardiac magnetic resonance imaging: a compressed-sensing framework incorporating sensor design and multidimensional signal reconstruction. Conventional Magnetic Resonance Imaging (MRI) technology is fundamentally constrained by slow scan speeds. Taking a new approach to cardiac imaging - which integrates MRI hardware design with a novel dynamic imaging method based on compressed sensing - this project enables faster and more accurate dynamic imaging for the diagnosis of heart disease.
Special Research Initiatives - Grant ID: SR0567334
Funder
Australian Research Council
Funding Amount
$125,748.00
Summary
A Grid-Enabled National Archive of Nanostructural Imagery (GRANI). The Nanostructural Analysis Network Organization (NANO) is an Australian Major National Research Facility that provides access to a grid of advanced microscopic instruments for the nanostructural analysis of both physical materials and biological systems. The aim of this initiative is to provide the NANO community with a set of common, interoperable tools and services to enable more efficient, cost-effective storage, management, ....A Grid-Enabled National Archive of Nanostructural Imagery (GRANI). The Nanostructural Analysis Network Organization (NANO) is an Australian Major National Research Facility that provides access to a grid of advanced microscopic instruments for the nanostructural analysis of both physical materials and biological systems. The aim of this initiative is to provide the NANO community with a set of common, interoperable tools and services to enable more efficient, cost-effective storage, management, analysis and sharing of generated microscopic images, video and analytical data. The significance of the proposed middleware is that it will improve collaboration and reduce duplication across many disciplines, through a shareable, distributed national scientific image/video database.Read moreRead less
Multi-modal, Multi-dimensional Virtual Microscopy for Diagnostic Quantitative Pathology. This project will contribute to the development of a new generation of virtual microscopy (VM) systems that provide new and innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of pathology. These systems have the potential to significantly enhance the efficiency and efficacy of not only primary diagnostic workflows, but also aspects of profi ....Multi-modal, Multi-dimensional Virtual Microscopy for Diagnostic Quantitative Pathology. This project will contribute to the development of a new generation of virtual microscopy (VM) systems that provide new and innovative features capable of significantly increasing the adoption of digital imaging technology throughout the field of pathology. These systems have the potential to significantly enhance the efficiency and efficacy of not only primary diagnostic workflows, but also aspects of proficiency testing and continuing education vital for a vibrant, well regulated discipline. In addition, the project will contribute to our knowledge of the pathology assessed in the screening and diagnosis of cancers such as cervical, lung and bladder cancers.Read moreRead less
System to synapse. Biological tissue is studied at the cellular and organ level with ever increasing clarity and sensitivity, but there are limitations in understanding how microscopic changes are manifested in the organ and vice versa. This project will develop new methods to bridge this gap and allow next generation correlative imaging.
Discovery Early Career Researcher Award - Grant ID: DE210101297
Funder
Australian Research Council
Funding Amount
$429,000.00
Summary
A novel, dictionary-free, multi-contrast MRI method for microscopic imaging. This project aims to develop a novel quantitative imaging technique for comprehensive in vitro and in vivo tissue characterisation on the microscopic scale. The technology innovated in the project could revolutionise microscopic imaging techniques by breaking through the sub-millimetre image resolution bottleneck of current magnetic resonance imaging (MRI) methods. This project expects to generate new knowledge in the e ....A novel, dictionary-free, multi-contrast MRI method for microscopic imaging. This project aims to develop a novel quantitative imaging technique for comprehensive in vitro and in vivo tissue characterisation on the microscopic scale. The technology innovated in the project could revolutionise microscopic imaging techniques by breaking through the sub-millimetre image resolution bottleneck of current magnetic resonance imaging (MRI) methods. This project expects to generate new knowledge in the emerging field of biological imaging and to deliver an integrated imaging platform for mapping various tissue microscopic components at the cellular level. Successful outcomes have the potential for commercialisation and will accelerate a range of fundamental science and engineering studies requiring imaging techniques.Read moreRead less
Special Research Initiatives - Grant ID: SR0354604
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Network in Imaging Science and Technology. The ARC Network in Imaging Science and Technology is a field of research network covering the fundamental science and technological development of applied imaging systems. The network will encompass all aspects of the imaging sciences from image formation, through image processing and analysis, and on to image visualisation. In particular, the network will focus on a number of application areas that utilise these core technologies: medical imaging; ....ARC Network in Imaging Science and Technology. The ARC Network in Imaging Science and Technology is a field of research network covering the fundamental science and technological development of applied imaging systems. The network will encompass all aspects of the imaging sciences from image formation, through image processing and analysis, and on to image visualisation. In particular, the network will focus on a number of application areas that utilise these core technologies: medical imaging; surveillance and security; materials science and metallurgy; environmental monitoring; and consumer imaging. In this way, the network will provide an environment for creative inter-disciplinary research to the socio-economic benefit of Australia.Read moreRead less
High resolution single particle analysis of biological macromolecules. One of the great challenges of cell biology is to increase the rate of atomic resolution structure determination, particularly of membrane proteins and macromolecular assemblies. The current rate-limiting step is high quality crystal production. Our goal is to prove that protein structures can be determined to atomic resolution by single-particle analysis. 3D structures will be produced by computationally aligning high-resolu ....High resolution single particle analysis of biological macromolecules. One of the great challenges of cell biology is to increase the rate of atomic resolution structure determination, particularly of membrane proteins and macromolecular assemblies. The current rate-limiting step is high quality crystal production. Our goal is to prove that protein structures can be determined to atomic resolution by single-particle analysis. 3D structures will be produced by computationally aligning high-resolution electron microscope images of individual, randomly oriented molecules. The importance of this project is highlighted by the fact over 120,000 protein sequences are already databased, a number set to increase rapidly as new genome sequencing projects are completed.
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