Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant ....Statistical Advances in the Post-Genome Era. Biologically relevant statistical foundations for post-genome biology and biotechnology will be developed. Specific goals of the topics include the development of accurate and more efficient algorithms for sequence alignments, improved models to maximise the accuracy of analyses for gene expression data and superior statistical methods for identification of complex gene networks that predispose an organism to disease. The Project will make significant contributions to the new and evolving priority research area of Bioinformation Science (including bioinformatics). Outcomes will include novel techniques for analysis and mining of post-genome data, with applications to developments in Bio-medicine and Bio-agricultureRead moreRead less
Sequence to Sequence: Rigorous Statistical and Mathematical Analysis of Biological Sequence Data. Comparative genomics is fundamental for developing an understanding of genes and their function. For example, using statistical and computational techniques, it was recently demonstrated that 60% of genes are conserved between fly and human. When the human gene that confers susceptibility to Parkinson's disease was transferred into the fly it caused symptoms similar to those seen in humans. The futu ....Sequence to Sequence: Rigorous Statistical and Mathematical Analysis of Biological Sequence Data. Comparative genomics is fundamental for developing an understanding of genes and their function. For example, using statistical and computational techniques, it was recently demonstrated that 60% of genes are conserved between fly and human. When the human gene that confers susceptibility to Parkinson's disease was transferred into the fly it caused symptoms similar to those seen in humans. The future development of 'personalized medicine' will rely upon understanding the function of human genes, as will progress in the agricultural sector. Rigorous statistical analysis and development of appropriate bioinformatic methods are crucial to biological sequence analysis in comparative genomics.Read moreRead less
Enabling Technologies for Structural Genomics. New technologies will be developed to save time, money and effort in rapid preparation of protein samples for structural genomics. Systems will be devised for preparing sufficient isotope-labelled proteins for nuclear magnetic resonance spectroscopy without using living organisms, for efficiently identifying points at which proteins can be broken into smaller fragments with the right properties, and for joining the ends of proteins and peptides toge ....Enabling Technologies for Structural Genomics. New technologies will be developed to save time, money and effort in rapid preparation of protein samples for structural genomics. Systems will be devised for preparing sufficient isotope-labelled proteins for nuclear magnetic resonance spectroscopy without using living organisms, for efficiently identifying points at which proteins can be broken into smaller fragments with the right properties, and for joining the ends of proteins and peptides together to make them much more stable. This combination of technologies are widely applicable to current problems in protein chemistry, molecular biology, functional genomics and the medical sciences.Read moreRead less
Special Research Initiatives - Grant ID: SR0354787
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 biorem ....Research Network for Biotechnological and Environmental Applications of Microalgae (BEAM). The network will facilitate inderdisciplinary and collaborative research into the limitations on microalgal growth leading to the development of new, commercial-scale microalgae culture systems, the production of fine chemicals, bioactive compounds and renewable fuels (hydrogen), as well as environmental applications such as monitoring the physiological state of phytoplankton in the environment, CO2 bioremediation and algal/bacterial systems for the bioremediation of contaminated soils. This will be achieved by applying research on photosynthetic light utilisation efficiency and carbon fixation, chlorophyll fluorescence, biochemistry of secondary metabolites, molecular biology and photobioreactor design and engineering, informed by an understanding of the ecology of these algae.Read moreRead less
Special Research Initiatives - Grant ID: SR0354797
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance co ....The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance communication, bring together innovative skill sets, create linkages, generate focussed research programs and foster novel commercial opportunities. Ultimately the Initiative and Network will deliver an improved quality of life, reduced healthcare costs, and increased productivity to Australia.Read moreRead less
ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functi ....ARC Research Network for Advanced Materials. Materials science/engineering is decidedly interdisciplinary, covering all science and impacting on all manufacturing industry. This network will promote interactions that do not usually occur between materials researchers and students across Australia and internationally from diverse disciplines. The scope is broadly based on advanced materials production, processing and properties but focused in four areas, involving: i) innovative structural/functional materials, ii) high-tech IT/communications/sensing materials, iii) materials solutions for manufacturing, iv) materials for a sustainable Australia, and v) emerging materials technologies. Key programs will promote interdisciplinary workshops and early career researcher interactions.Read moreRead less
Special Research Initiatives - Grant ID: SR0354605
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high per ....The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high performance computing through open sourced middleware. The result will be an unparalleled predictive capacity for complex Earth systems. The outcome will be confidence in the knowledge that underpins our decisions as stakeholders to keep Australia sustainable.Read moreRead less
Uncoupling past salinity and temperature signals in the Indo-Pacific Warm Pool: implications for climate change in the Australian region. The tropical oceans and in particular the Indo-Pacific Warm Pool, immediately to Australia's north, play a key role in modulating global and Australian climate through El-Niño and related phenomena. Using a new microanalysis approach to analyse individual foraminifera from deep-sea cores, we will reconstruct past salinity and temperature variability within the ....Uncoupling past salinity and temperature signals in the Indo-Pacific Warm Pool: implications for climate change in the Australian region. The tropical oceans and in particular the Indo-Pacific Warm Pool, immediately to Australia's north, play a key role in modulating global and Australian climate through El-Niño and related phenomena. Using a new microanalysis approach to analyse individual foraminifera from deep-sea cores, we will reconstruct past salinity and temperature variability within the Warm Pool, and determine changing rainfall patterns and, ENSO and monsoon behaviour under climate conditions that lie outside modern records. This information is vital for understanding past climate and predicting the future intensity and frequency of El-Niño related drought and wet cycles in Australia.Read moreRead less
ARC Nanotechnology Research Network. The field of nano scale science, engineering and technology (in short nanotechnology) is just emerging and it is predicted to make a major impact in all technologies and areas of society. Australian Nanotechnology Network intends to harness the combined Australian capability to enable Australia to take a leading role in this rapidly growing field.
Special Research Initiatives - Grant ID: SR0354623
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
Network for Australian security technologies integration. The frontline of community safety is security technologies which include sensors to track movements and conversations of suspects; signal processing techniques for extracting information; intelligent search/audit techniques to track financial transactions; analysis techniques for predicting the spread of epidemic; and above all human factors in security operations. The aim of this initiative is to establish a network for "safeguarding Aus ....Network for Australian security technologies integration. The frontline of community safety is security technologies which include sensors to track movements and conversations of suspects; signal processing techniques for extracting information; intelligent search/audit techniques to track financial transactions; analysis techniques for predicting the spread of epidemic; and above all human factors in security operations. The aim of this initiative is to establish a network for "safeguarding Australia". This network, built on the concept of "network of networks", draws on the expertise of researchers and practitioners from diverse fields to provide an integrated approach towards development and use of security technologies for the safety of the community.Read moreRead less