Enhancing biopharmaceuticals: A disruptive bioseparation resin technology. This project aims to develop an innovative and disruptive platform technology for designing and manufacturing tailor-made high-performance bioseparation resins to enhance biopharmaceuticals manufacturing. Bacterial cell factories will be developed to enable biotechnological production of innovative polyester bead-based bioseparation resins, which will revolutionise manufacturing of biopharmaceuticals. Expected outcomes o ....Enhancing biopharmaceuticals: A disruptive bioseparation resin technology. This project aims to develop an innovative and disruptive platform technology for designing and manufacturing tailor-made high-performance bioseparation resins to enhance biopharmaceuticals manufacturing. Bacterial cell factories will be developed to enable biotechnological production of innovative polyester bead-based bioseparation resins, which will revolutionise manufacturing of biopharmaceuticals. Expected outcomes of this project are cost-effective and strongly enhanced approaches for biopharmaceuticals recovery, thereby providing significant benefits to accelerate research and development in early stage discovery and manufacture of biologics, therapeutic proteins and vaccines.Read moreRead less
Accelerating pulse breeding using machine learning. Advances in genomics and high throughput phenotyping are generating vast quantities of data that can be applied for crop improvement, however the lack of computational analysis tools and approaches limits the full exploitation of this data. Pulse legumes are currently under utilised in Australian agriculture due to poor adaptation, however they offer significant benefits both for soil improvement and the production of high protein crops. This p ....Accelerating pulse breeding using machine learning. Advances in genomics and high throughput phenotyping are generating vast quantities of data that can be applied for crop improvement, however the lack of computational analysis tools and approaches limits the full exploitation of this data. Pulse legumes are currently under utilised in Australian agriculture due to poor adaptation, however they offer significant benefits both for soil improvement and the production of high protein crops. This project will develop machine learning (ML) tools for the analysis of pulse legume crop traits and their association with genomic variation to accelerate the breeding of high performance pulse legumes for Australian growers.Read moreRead less
Superior Australian psyllium for functional foods. This project aims to establish a breeding program for Plantago ovata in Australia to provide a reliable supply of high quality, superior psyllium as a key ingredient in the gluten-free food industry, providing benefits to the industrial partner, growers in Australia and consumers. Target traits include better harvest index, reduced seed shattering and identification of lines carrying psyllium with novel properties or whole seeds that can be grou ....Superior Australian psyllium for functional foods. This project aims to establish a breeding program for Plantago ovata in Australia to provide a reliable supply of high quality, superior psyllium as a key ingredient in the gluten-free food industry, providing benefits to the industrial partner, growers in Australia and consumers. Target traits include better harvest index, reduced seed shattering and identification of lines carrying psyllium with novel properties or whole seeds that can be ground and used as flour that imparts less intense colour changes or effects on loaf structure, and which may be highly suitable for other baked gluten-free products. The fundamental knowledge gained from the genetic and biochemical anlayses of these lines will also broadly benefit seed biology research.Read moreRead less
Building a CO2 foundry for sustainable carbon capture and utilisation. This project aims to develop innovative carbon capture and utilisation technology that fuses synthetic biology with inorganic chemistry. The project expects to develop nano-structured electrocatalysts to efficiently convert CO2 from industrial emission into acetate, and genetically-engineered microbes to rapidly transform acetate into platform chemicals and biopolymers. Expected outcomes include an integrated electro-/biocata ....Building a CO2 foundry for sustainable carbon capture and utilisation. This project aims to develop innovative carbon capture and utilisation technology that fuses synthetic biology with inorganic chemistry. The project expects to develop nano-structured electrocatalysts to efficiently convert CO2 from industrial emission into acetate, and genetically-engineered microbes to rapidly transform acetate into platform chemicals and biopolymers. Expected outcomes include an integrated electro-/biocatalytic prototype with unprecedented CO2 conversion efficiency, as well as building a multidisciplinary research capacity in synthetic biology and nanotechnology. This should provide significant benefits, by reducing greenhouse gases and providing the basis for a carbon-negative chemical industry.Read moreRead less
Dual-membrane upgrading towards sustainable wastewater management. Water utilities in Australia have set aspirational targets for energy- and carbon-neutral wastewater services by as early as 2030. However, these two aims are often incompatible because of excessive aeration energy consumption and substantial greenhouse gas emissions in wastewater treatment plants. This project aims to develop a novel biotechnology that enables simultaneous bioenergy recovery, cost-efficient nitrogen removal and ....Dual-membrane upgrading towards sustainable wastewater management. Water utilities in Australia have set aspirational targets for energy- and carbon-neutral wastewater services by as early as 2030. However, these two aims are often incompatible because of excessive aeration energy consumption and substantial greenhouse gas emissions in wastewater treatment plants. This project aims to develop a novel biotechnology that enables simultaneous bioenergy recovery, cost-efficient nitrogen removal and mitigation of greenhouse gas emissions, thus bringing multifaceted benefits to wastewater management. The project will provide strong support to the Australian water industry in their endeavour to achieve economically and environmentally sustainable wastewater services.Read moreRead less
Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH210100025
Funder
Australian Research Council
Funding Amount
$4,379,165.00
Summary
ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D). Australia holds large resources of critical 2D minerals – key enablers of several existing and emerging technologies in Energy Storage, Purification and Printed Electronics. The AM2D hub aims to provide a sophisticated environment for researchers and an industrial translation platform for manufacturers; a hub where leading academics, bright students, and industry partners come together to learn, apply, collaborate, innovate, a ....ARC Research Hub for Advanced Manufacturing with 2D Materials (AM2D). Australia holds large resources of critical 2D minerals – key enablers of several existing and emerging technologies in Energy Storage, Purification and Printed Electronics. The AM2D hub aims to provide a sophisticated environment for researchers and an industrial translation platform for manufacturers; a hub where leading academics, bright students, and industry partners come together to learn, apply, collaborate, innovate, and deliver industry transformation in advanced manufacturing. Anticipated outcomes include the transformation of newly discovered materials into globally traded, high-value 2D products, enabling Australian industries to capture more wealth and jobs from this large and growing market.
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Accelerated tailings remediation with plant and microbial biotechnologies. The Australian alumina industry produces 32 million tonnes of bauxite residue (alumina refining tailings) each year, most of which is stored in perpetuity in landfill-type tailings storage facilities. The high pH, high salinity, lack of plant nutrients, and poor physical properties of bauxite residue are major barriers to safe storage and successful closure of tailings storage facilities. Existing remediation approaches a ....Accelerated tailings remediation with plant and microbial biotechnologies. The Australian alumina industry produces 32 million tonnes of bauxite residue (alumina refining tailings) each year, most of which is stored in perpetuity in landfill-type tailings storage facilities. The high pH, high salinity, lack of plant nutrients, and poor physical properties of bauxite residue are major barriers to safe storage and successful closure of tailings storage facilities. Existing remediation approaches are expensive, slow, and often ineffective. We will deliver new microbial- and plant-driven biotechnologies for rapid, cost-effective remediation of bauxite residue. This will enable safe, sustainable closure of storage facilities, and safeguard the strong contribution of this $15 billion industry to Australia's economy. Read moreRead less
Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty a ....Enabling three dimensional stochastic geological modelling. This project aims to develop technologies to mitigate three dimensional (3D) geological risk in resources management. This project expects to create new knowledge and methods in the field of 3D geological modelling through the innovative application of mathematical methods, structural geology concepts and probabilistic programming. The expected outcomes are an enhanced capability to model the subsurface, characterise model uncertainty and test multiple geological scenarios. This enhanced capability is important for the future of Australia's subsurface management, including urban geology and our continuously growing sustainable resources industry.Read moreRead less
Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforceme ....Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforcement systems to provide a comprehensive account of social and criminal justice impacts of injection drug use and methamphetamine use in Australia for the first time. Read moreRead less