Role Of Resident Endothelial Progenitor Cells In Melanoma Vascularisation And Progression
Funder
National Health and Medical Research Council
Funding Amount
$952,328.00
Summary
Melanoma is one of the most frequent cancers in Australia. Its growth depends on the rpoper delivery of nutrients and oxygen through blood vessels. This requires the formation of new blood vessels as the tumour grows. In this project we intend to understand the origin of the blood vessels that form in tumours and identify the stem cells that support them. We will use proof of principle experiments to determine whether removal of these stem cells allows the regression of melanoma tumours.
Investigating the educational impact of wildlife-based leisure experiences in supporting visitors? adoption of environmentally sustainable practices. National environmental policy makers acknowledge the central role education plays in addressing the many serious environmental problems facing the country and encouraging Australians to adopt environmentally sustainable practices. This project will inform the design of free-choice, wildlife-based learning experiences that are relevant, meaningful a ....Investigating the educational impact of wildlife-based leisure experiences in supporting visitors? adoption of environmentally sustainable practices. National environmental policy makers acknowledge the central role education plays in addressing the many serious environmental problems facing the country and encouraging Australians to adopt environmentally sustainable practices. This project will inform the design of free-choice, wildlife-based learning experiences that are relevant, meaningful and accessible to the majority of society. Wildlife-based learning experiences offer a way to secure sustainable economic benefits while supporting both wildlife conservation and local communities. By developing new tools to assess and enhance the educational impact of such experiences this project will contribute to building the capacity of visitors to adopt environmentally sustainable practices.Read moreRead less
Learning for sustainability: The role and impact of Outdoor and Environmental Education Centres. The proposed research will contribute to the National Research Priority for an Environmentally Sustainable Australia by addressing the effectiveness of educational interventions. Education plays a key role in providing the means and knowledge to address environmental issues, and research indicates that direct experiences with nature are a critical component. In Queensland, such experiences are provi ....Learning for sustainability: The role and impact of Outdoor and Environmental Education Centres. The proposed research will contribute to the National Research Priority for an Environmentally Sustainable Australia by addressing the effectiveness of educational interventions. Education plays a key role in providing the means and knowledge to address environmental issues, and research indicates that direct experiences with nature are a critical component. In Queensland, such experiences are provided by Outdoor and Environmental Education Centres (O&EECs). This research will advance our theoretical understanding of the role and impact of nature-based environmental learning experiences, identify factors that facilitate learning for sustainability, and develop empirically-based principles to support O&EECs in providing effective education for sustainability.Read moreRead less
Environmental change in northern Cenozoic Australia: a multidisciplinary approach. The Intergovernmental Panel on Climate Change (IPCC) warned that by 2020 to 2050, Australia will suffer significant biodiversity loss and water shortages. Our research will document and date the evolution of Australia's biota through three cycles of climate change over the last 25 million years to quantify and thereby better anticipate the nature and dimension of threats facing our natural and cultural communities ....Environmental change in northern Cenozoic Australia: a multidisciplinary approach. The Intergovernmental Panel on Climate Change (IPCC) warned that by 2020 to 2050, Australia will suffer significant biodiversity loss and water shortages. Our research will document and date the evolution of Australia's biota through three cycles of climate change over the last 25 million years to quantify and thereby better anticipate the nature and dimension of threats facing our natural and cultural communities. We will develop innovative techniques to date prehistoric biotic and climatic events and, using a range of tracers, characterize ancient environments and groundwater. This project will assist rural and regional Australia through education and job creation in geotourism and natural resource interpretation and provide a mechanism to combat generational skill shortage.Read moreRead less
The evolution of Australian rainforest faunas and the implications of continuing climate change. Australia's rainforest animals and ecosystems have been evolving for millions of years yet we routinely use only the last 200 years to assess changes that will affect their future - far too short a time interval to distinguish short-term perturbations from long-term trends in lineage health or community response. Our multidisciplinary team proposes to learn from 55 million years of response to rainfa ....The evolution of Australian rainforest faunas and the implications of continuing climate change. Australia's rainforest animals and ecosystems have been evolving for millions of years yet we routinely use only the last 200 years to assess changes that will affect their future - far too short a time interval to distinguish short-term perturbations from long-term trends in lineage health or community response. Our multidisciplinary team proposes to learn from 55 million years of response to rainfall and other climate change documented by the spectacular national, natural treasures in the fossil deposits of Tingamarra, Riversleigh and Rockhampton, to assess probable impacts of future environmental change and inform development of effective, long-term conservation strategies for rainforest communities. Read moreRead less
The skin of commerce: the role of plastic packaging in the construction of food security, waste and consumer activism in Australia. Plastic packaging has been important to ensuring food security in Australia, however it is also a major waste burden. This project will critically assess new approaches to reducing plastic packaging in food markets and waste streams and will produce key insights into how sustainable food systems can be organised with less reliance on plastic.
An Assessment of Social-Ecological Resilience in the Context of Marine Resource Management in Melanesia. Papua New Guinea and Solomon Islands are part of the so-called 'Arc of Instability'. Despite enjoying relatively high levels of food security, mainly due to low human population densities, both countries have low Human Development Indices, particularly in Health and Education, and sustainable development is hindered by a range of problems, including complex and often socially destructive resp ....An Assessment of Social-Ecological Resilience in the Context of Marine Resource Management in Melanesia. Papua New Guinea and Solomon Islands are part of the so-called 'Arc of Instability'. Despite enjoying relatively high levels of food security, mainly due to low human population densities, both countries have low Human Development Indices, particularly in Health and Education, and sustainable development is hindered by a range of problems, including complex and often socially destructive responses to global markets. Meanwhile fishery resources of both countries are being rapidly depleted by accelerating global commodity demand, threatening food security and undermining progress towards sustainable human development. Targeted, socially-informed resource management policy can prevent these problems from becoming ours as well.Read moreRead less
Special Research Initiatives - Grant ID: SR0354804
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impac ....ARC Research Network on Degraded Environment Assessment and Remediation. There are over 80,000 contaminated sites in Australia and >750,000,000 hectares of land impacted by soil acidity, sodicity, heavy-metals, nutrients and agricultural chemicals. The research network advances assessment, management and remediation of degraded environments (land, water, and air) through collaboration of the research programs developing sustainable solutions. The collective focus is minimising disposal and impacts of contaminated soil and wastes, and land remediation. By facilitating communication, the network enhances national and international research coordination, interaction with regulators, end-users, industry, and other stakeholders, achievement of critical mass for new initiatives, enhances research training and contributes to a critical National Priority.Read moreRead less
The Devonian Gogo Fauna: Diversity, Palaeoecology and Global Significance. The late Devonian Gogo Formation (380 million years old) is undoubtedly one of the richest and best-preserved assemblages of fossil fishes and invertebrates from this age anywhere on Earth. This project will use CT scanning for stomach contents, plus use biomechanical and morphometric analyses to reconstruct tropic relationships of reef-dwelling organisms and test the resilience of the reef ecosystem. Several new species .... The Devonian Gogo Fauna: Diversity, Palaeoecology and Global Significance. The late Devonian Gogo Formation (380 million years old) is undoubtedly one of the richest and best-preserved assemblages of fossil fishes and invertebrates from this age anywhere on Earth. This project will use CT scanning for stomach contents, plus use biomechanical and morphometric analyses to reconstruct tropic relationships of reef-dwelling organisms and test the resilience of the reef ecosystem. Several new species will be published and the heritage significance of the site will be assessed. Working with local indigenous stakeholders, the scientific findings will feed into developing a long-term management plan to protect and conserve the site for future research work and to grow tourism in the region.Read moreRead less