Characterisation Of Human Embryonic Stem Cell Differentiation To Haematopoietic Progenitors And Stem Cells
Funder
National Health and Medical Research Council
Funding Amount
$638,856.00
Summary
Blood stem cells, which are found in the bone marrow, are currently used for treating human blood disorders including leukemia and lymphoma. However, for the majority of bone marrow transplant candidates, suitable donors cannot be found. Using embryonic stem cells, this project aims to define the conditions required to generate blood stem cells in the laboratory. The aim of the work is to provide a new source of blood stem cells that could be used in place of donor derived bone marrow.
Simulating And Stimulating The Blood-Brain-Barrier: A Platform For Investigating Non-pharmaceutical Alzheimer's Therapy
Funder
National Health and Medical Research Council
Funding Amount
$680,758.00
Summary
Alzheimer's disease is a looming public health threat worldwide. Despite the widespread acknowledgement of this issue, there are a lack of effective drugs that can slow disease progression. This project aims to investigate a new class of non-pharmaceutical treatment methods based on controlled acoustic, electrical and optical stimulation methods to treat and reverse the base causes of Alzheimer's disease.
Future Proofing Schools: using smart green integrated design approaches to prefabricated learning environments. This project draws on multi-disciplinary approaches to set the groundwork of major transformations of prefabricated classrooms, with the use of advanced materials, smart information systems embedded in the classrooms, better placement on sites, and use of more efficient construction techniques, allowing a transformation of this Australian industry. Our research will promote an innovati ....Future Proofing Schools: using smart green integrated design approaches to prefabricated learning environments. This project draws on multi-disciplinary approaches to set the groundwork of major transformations of prefabricated classrooms, with the use of advanced materials, smart information systems embedded in the classrooms, better placement on sites, and use of more efficient construction techniques, allowing a transformation of this Australian industry. Our research will promote an innovation culture and economy within the school and for future generations, and will have flow-on effects into promoting a healthy start to life in which smart, green, and educational imperatives are aligned. This will assist in strengthening Australia's social and economic fabric. Read moreRead less
Smart Green Schools: Educational and Environmental Outcomes of Innovation in School Building Design. The research touches upon many of the key National Research Priorities. Children spend a large proportion of their waking hours within a school environment. A healthy school environment which efficiently uses energy resources and information technology will help ' strengthen Australia's social economic fabric' in the longer term and support student engagement. Children's inhabitation of virtual s ....Smart Green Schools: Educational and Environmental Outcomes of Innovation in School Building Design. The research touches upon many of the key National Research Priorities. Children spend a large proportion of their waking hours within a school environment. A healthy school environment which efficiently uses energy resources and information technology will help ' strengthen Australia's social economic fabric' in the longer term and support student engagement. Children's inhabitation of virtual space as 'native' users of information rich 'frontier technologies' will be complemented by buildings acting as 3D textbooks educating children about an 'environmentally sustainable Australia' and providing feedback on design innovations intended to save 'water' and 'minimise environment impacts' on land and climate.Read moreRead less
Developing Effective School-Community Learning Partnerships for Sustainability. The research contributes to 2 areas of national concern:achieving environmental sustainability and strengthening social cohesion, especially in the expanding urban growth corridors of Australian cities. It will develop guidelines for facilitating models of community learning partnerships that build social capital as a vehicle for protecting natural capital. Knowledge generated will advance conservation practices for ....Developing Effective School-Community Learning Partnerships for Sustainability. The research contributes to 2 areas of national concern:achieving environmental sustainability and strengthening social cohesion, especially in the expanding urban growth corridors of Australian cities. It will develop guidelines for facilitating models of community learning partnerships that build social capital as a vehicle for protecting natural capital. Knowledge generated will advance conservation practices for natural capital:water, energy, biodiversity and waste, and strengthen the school-community partnership elements of programs such as ResourceSmart and the Australian Sustainable Schools Initiative (AuSSI), supported extensively by networks of local, State and Commonwealth governments, schools and community groups.Read moreRead less
Modelling Of Clinic And Ambulatory Blood Pressure On Cardiovascular Risk And Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$133,957.00
Summary
Whilst ambulatory blood pressure monitoring data has been shown to be a good predictor of cardiovascular events, there remains controversy as to its utility in clinical practice. This project will use data from existing population and clinical cohort studies to examine the role of ambulatory blood pressure in risk assessment and hypertension management in Australia and around the globe. The findings are likely to have a major impact on clinical guidelines for hypertension management.
Understanding The Origins Of Neurogenic Hypertension
Funder
National Health and Medical Research Council
Funding Amount
$668,914.00
Summary
Brain cells that control the cardiovascular system are thought to have stopped dividing by adulthood. We recently discovered that this is not the case. Our initial findings suggest that these nascent cells might be important for maintaining normal blood pressure. This work will allow us to elucidate the function of these nascent cells and how they integrate into the circuit that controls the cardiovascular system. Our findings will be fundamental for understanding diseases such as hypertension.
Building Capacity for a Sustainable Future. The concept of sustainability has been proposed as a practical and useful concept capable of providing solutions to social, environmental and economic problems. Global interest in the concept also stems from the advantages that organisational change for sustainability can impart, including improved efficiency and profitability. The project will develop sustainability capabilities of graduates entering a diverse range of industries, enhancing the nation ....Building Capacity for a Sustainable Future. The concept of sustainability has been proposed as a practical and useful concept capable of providing solutions to social, environmental and economic problems. Global interest in the concept also stems from the advantages that organisational change for sustainability can impart, including improved efficiency and profitability. The project will develop sustainability capabilities of graduates entering a diverse range of industries, enhancing the national skills base. The models and processes of institutional change developed in this project can be adopted by universities, governments and corporations throughout the world, enhancing Australia's reputation as a world leader in institutional and corporate sustainability.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220100103
Funder
Australian Research Council
Funding Amount
$454,582.00
Summary
Striking voices: Australian school-aged students' climate justice activism. Mass student-led climate justice activism emerged as a transnational phenomenon in 2018.This project aims to foster understanding of this phenomenon, through exploring how Australian young people are taking action on climate change, the supports for their activism, and educational conditions of and responses to their climate concerns, using ethnographic and participatory methods. Expected outcomes include online student- ....Striking voices: Australian school-aged students' climate justice activism. Mass student-led climate justice activism emerged as a transnational phenomenon in 2018.This project aims to foster understanding of this phenomenon, through exploring how Australian young people are taking action on climate change, the supports for their activism, and educational conditions of and responses to their climate concerns, using ethnographic and participatory methods. Expected outcomes include online student-curated accounts of social movement participation, and a co-produced teaching and learning framework for schools. Anticipated benefits include a greater understanding of emerging patterns of political engagement, and the development of educational capacity to engage young people and face urgent environmental challenges.Read moreRead less
Reducing Morbidities In Preterm Growth Restricted Neonates.
Funder
National Health and Medical Research Council
Funding Amount
$687,214.00
Summary
Intrauterine growth restriction (IUGR) is a serious complication of pregnancy and occurs when fetal growth is abnormal, resulting in a fetus that is smaller than it should be for its given gestational age. IUGR babies are at much greater risk of many short and long-term adverse outcomes. This study investigates the role that adverse cardiovascular development plays in the progression of lung, heart and brain disease in preterm IUGR newborns.