The Implementation Of MinimAlly INvasivE Hysterectomy (IMAGINE) Trial
Funder
National Health and Medical Research Council
Funding Amount
$656,854.00
Summary
Hysterectomy is the most common surgical [procedure among Australian women. Too many women still receive an open abdominal surgery, because too few Australian obstetricians and gynaecologists practice laparoscopic hysterectomy. This partnership will develop a model to systematically train practicing surgeons in advanced laparoscopic techniques. If successful, the model can be rolled out state and nationwide and also adapted for teaching future innovations in surgery.
The Barrow Island archaeology project: the dynamism of maritime societies in northern Australia. This project will study human occupation from exceptionally rich sites on Barrow Island, located off northwest Australia, profiling a continuous reliance on coastal resources until isolation. Whaling and pearling started in the nineteenth century using Indigenous labourers after a 7,000 year gap in human occupation.
Mapping Aboriginal routes to link landscape knowledge and cultural identity. Mapping Aboriginal routes to link landscape knowledge and cultural identity. This project aims to develop novel methods for Aboriginal communities to describe and share place-based knowledge of cultural landscapes using historical travel routes. This is a priority to reconnect people to their cultural identify and uncover significant heritage trails in southeast Queensland. The Wakka Wakka people will train Indigenous y ....Mapping Aboriginal routes to link landscape knowledge and cultural identity. Mapping Aboriginal routes to link landscape knowledge and cultural identity. This project aims to develop novel methods for Aboriginal communities to describe and share place-based knowledge of cultural landscapes using historical travel routes. This is a priority to reconnect people to their cultural identify and uncover significant heritage trails in southeast Queensland. The Wakka Wakka people will train Indigenous youth in geographic information system (GIS) technologies to collect place-based stories from elders, thus transferring knowledge between generations. The spatial rendering of cultural landscapes through story maps and participatory mapping is expected to enhance Indigenous cultural identity and awareness, build social capital, and document current and historical connections to 'country'.Read moreRead less
What could World Heritage listing deliver for Indigenous people? The Australian experience in global context. This project investigates the difference between the intentions of the World Heritage system regarding Indigenous people and what it actually delivers. There is almost no research on this issue despite United Nations Educational, Scientific and Cultural Organisation's (UNESCO) aim to expand the non-Western dimensions of the World Heritage program. The study will develop innovative method ....What could World Heritage listing deliver for Indigenous people? The Australian experience in global context. This project investigates the difference between the intentions of the World Heritage system regarding Indigenous people and what it actually delivers. There is almost no research on this issue despite United Nations Educational, Scientific and Cultural Organisation's (UNESCO) aim to expand the non-Western dimensions of the World Heritage program. The study will develop innovative methods that integrate Western and Indigenous knowledge, substantially boosting knowledge of Indigenous perspectives on World Heritage. The outcome will be an evidence-based model that better mediates UNESCO's universalising approach with the particular interests of Indigenous communities, assisting the global 'heritage industry' to address the complex demands of the postcolonial era.Read moreRead less
Exploring The Function Of Breast Cancer-Associated Variants In Long Non-Coding RNAs
Funder
National Health and Medical Research Council
Funding Amount
$501,585.00
Summary
Recent studies have identified regions within the human genome in which DNA sequence variations are associated with an increased risk of breast cancer. Several of these regions do not contain any known protein coding genes, suggesting that non-protein coding genes could be responsible for the associated risk. The aim of this proposal is to identify and characterise these non-coding genes. Understanding how sequences variations in these novel genes contribute to breast cancer will provide novel a ....Recent studies have identified regions within the human genome in which DNA sequence variations are associated with an increased risk of breast cancer. Several of these regions do not contain any known protein coding genes, suggesting that non-protein coding genes could be responsible for the associated risk. The aim of this proposal is to identify and characterise these non-coding genes. Understanding how sequences variations in these novel genes contribute to breast cancer will provide novel avenues for therapy.Read moreRead less
A national framework for managing malignant plastics in museum collections. A national framework for managing malignant plastics in museum collections. This collaborative project between three universities, four museums and an art gallery aims to discover how to predict and increase the lifespan of malignant plastics or polymers by studying their identification, deterioration and conservation. 5 to 80% of museum collections, composed of growing numbers of plastic or polymer-based materials, need ....A national framework for managing malignant plastics in museum collections. A national framework for managing malignant plastics in museum collections. This collaborative project between three universities, four museums and an art gallery aims to discover how to predict and increase the lifespan of malignant plastics or polymers by studying their identification, deterioration and conservation. 5 to 80% of museum collections, composed of growing numbers of plastic or polymer-based materials, need better preservation. Conservators do not have much expertise in preserving plastics, which are contemporary and have a relatively short life expectancy. This project intends to provide museums with a model for prioritising and effectively allocating resources to preserve a vulnerable group of collections for future generations.Read moreRead less
Identifying Novel Long-noncoding RNAs Involved In The Development Of Breast Cancer
Funder
National Health and Medical Research Council
Funding Amount
$785,204.00
Summary
Recent studies have identified regions within the human genome in which DNA sequence variations are associated with an increased risk of breast cancer. The aim of this proposal is to identify and characterise these non-coding genes that are modulate breast cancer risk. Understanding how sequences variations that alter these novel genes contribute to breast cancer will provide novel avenues for therapy.
We have identified genetic abnormalities in 5% of breast cancers that fall in a novel DNA element called BIME1. This proposal aims to determine whether these genetic abnormalities contribute to breast tumourigenesis and which genes and pathways are affected by these mutations. The outcomes of this proposal may lead to the development of novel therapies for breast cancer or could influence the choice of existing therapies for patients that harbour these genetic abnormalities.
The Nakanai Caves Cultural Heritage Project. This project aims to document and integrate the natural and cultural values of the Nakanai Caves in East New Britain, Papua New Guinea, in preparation for a cultural landscape World Heritage nomination. The project’s novel methodology incorporates community knowledge with archaeological and anthropological evidence to link natural and cultural values and define the landscape from local perspectives. Local input into the research will be prioritised. B ....The Nakanai Caves Cultural Heritage Project. This project aims to document and integrate the natural and cultural values of the Nakanai Caves in East New Britain, Papua New Guinea, in preparation for a cultural landscape World Heritage nomination. The project’s novel methodology incorporates community knowledge with archaeological and anthropological evidence to link natural and cultural values and define the landscape from local perspectives. Local input into the research will be prioritised. By emphasising local participation and management of World Heritage listing processes the project aims to address an identified gap in World Heritage methodologies. This project allows for a subtle, nuanced definition of cultural landscapes under the World Heritage Convention.Read moreRead less
Archaeology, collections and Australian South Sea Islander. This project aims to integrate archaeology, museology, and cultural landscape research to weave together histories of Australian South Sea Islanders’ (ASSIs) lives and communities. ASSIs are not indigenous to Australia, nonetheless they have a distinctive and vibrant indigenous culture. With little written about ASSIs, most of their stories are in the places that they have inhabited, and in the objects they have left behind. In partners ....Archaeology, collections and Australian South Sea Islander. This project aims to integrate archaeology, museology, and cultural landscape research to weave together histories of Australian South Sea Islanders’ (ASSIs) lives and communities. ASSIs are not indigenous to Australia, nonetheless they have a distinctive and vibrant indigenous culture. With little written about ASSIs, most of their stories are in the places that they have inhabited, and in the objects they have left behind. In partnership with living ASSI communities, this project will raise awareness about their past in Queensland society and contribute to their sense of identity in the present and future.Read moreRead less