Safety And Efficacy Of A Surgically Implanted Suprachoroidal Retinal Prosthesis (Bionic Eye)
Funder
National Health and Medical Research Council
Funding Amount
$1,233,826.00
Summary
A bionic eye is a electronic device which can stimulate the remaining visual pathway in a person who is blind, to restore some basic vision. Our team have previously shown that our novel bionic eye device can be safely implanted in a patient, and can give improvements in vision when tested in a laboratory environment. The next stage of the research is to provide patients with a more advanced device, which will contain more electrodes and also be able to be taken home.
The Crisis in International Heritage Conservation in an Age of Shifting Global Power. This project responds to the current crisis in international heritage conservation at a time of shifting global power. The flagship of heritage conservation, the world heritage system, faces multiple pressures and agendas that endanger sites and politicise decision-making at all levels, from local to global. This project focuses on four iconic sites, Abu Simbel, Angkor, Bagan and Sumatran Rainforests, and the w ....The Crisis in International Heritage Conservation in an Age of Shifting Global Power. This project responds to the current crisis in international heritage conservation at a time of shifting global power. The flagship of heritage conservation, the world heritage system, faces multiple pressures and agendas that endanger sites and politicise decision-making at all levels, from local to global. This project focuses on four iconic sites, Abu Simbel, Angkor, Bagan and Sumatran Rainforests, and the world heritage system itself, to reveal how pressures have grown and shifted since World War II, how they operate at multiple scales and what new expertise might be introduced. It will produce a report for UNESCO and publications that include recommendations for solving challenges that threaten international heritage conservation today.Read moreRead less
A Systematic Evaluation Of The Neurosurgical Application Of Peri-operative And Intra-operative MR Tractography In Different Paediatric Disease States
Funder
National Health and Medical Research Council
Funding Amount
$130,910.00
Summary
My research investigates changes in brain nerve fibre tracts/white matter in paediatric disease states and changes related to surgery by using nerve fibre tract imaging before, during and after surgery. It will also generate an imaging atlas to help understand white matter pathway development. It then serves as normative comparison to better understand aberrations in diseased neural pathways. The outcome will aid understanding in brain development, recovery and plasticity, and helps improve whit ....My research investigates changes in brain nerve fibre tracts/white matter in paediatric disease states and changes related to surgery by using nerve fibre tract imaging before, during and after surgery. It will also generate an imaging atlas to help understand white matter pathway development. It then serves as normative comparison to better understand aberrations in diseased neural pathways. The outcome will aid understanding in brain development, recovery and plasticity, and helps improve white matter lesion localisation.Read moreRead less
Improving The Long-term Outcomes Of The Australian And New Zealand Fontan Population
Funder
National Health and Medical Research Council
Funding Amount
$89,836.00
Summary
The Fontan procedure is the last of a series of operations offered to children born with hearts with a single pumping chamber. Without this procedure these children would die, however, with this procedure their long-term expectations are still uncertain. This study will investigate the long-term outcomes of the Australian and New Zealand Fontan population and how these outcomes can be improved.
Reduction Of Chronic Post-surgical Pain With Ketamine - ROCKet Study
Funder
National Health and Medical Research Council
Funding Amount
$4,823,395.00
Summary
Chronic post-surgical pain (CPSP) is a common complication of major surgery, and a significant burden on quality of life and ongoing health costs. Ketamine is a drug used by anaesthetists to treat severe acute surgical pain. Various small studies suggest that it may be unique in its ability to reduce the risk of CPSP. We propose a large trial of ketamine during & after anaesthesia for major surgery to test this. Demonstration of effectiveness would promote widespread change in clinical practice.
Regulation Of Key Pathways Causing Peri-implant Bone Loss.
Funder
National Health and Medical Research Council
Funding Amount
$403,639.00
Summary
The failure of bone prostheses is becoming a major health problem in our aging population. Despite the impressive success of joint replacement surgery, a significant number of arthroplasties fail. It is now apparent that most implants fail due to bone loss around them which leads to loosening. This project aims to obtain a better understanding of the causes of implant failure and find ways to extend the life of these implants .
Clinical Trial Of A Suprachoroidal Visual Prosthesis For The Profoundly Vision Impaired
Funder
National Health and Medical Research Council
Funding Amount
$1,098,802.00
Summary
For 15 years we have been designing a bionic eye. We have made a device called the Phoenix99 and shown in short term animal tests that it is both safe to implant but also that it potentially performs better than any other device in the world. We are requesting funds to complete longer term animal testing of the device and then commence a small human clinical trial to demonstrate the benefits of the technology – specifically that it is able to help blind people navigate without assistance.
Predicting Fracture Outcomes From Clinical Registry Data Using Artificial Intelligence Supplemented Models For Evidence-informed Treatment (PRAISE) Study
Funder
National Health and Medical Research Council
Funding Amount
$636,217.00
Summary
This project will establish the role of artificial intelligence (AI) techniques to improve the prediction of clinical and longer-term patient reported outcomes following wrist fracture. Prediction models based on existing, routinely collected registry data with will be compared with models based on registry data enhanced by AI analysis of X-ray images, radiology reports and surgical reports. The AI analysis will reason on both image and text data, better replicating how humans learn.
Snails to the rescue! Conservation of Australia’s island invertebrates. This project aims to deliver an exemplar industry network model for conservation on Australia’s islands which are hotspots both of biodiversity and of extinctions. Protecting species on islands is therefore key to securing Australia’s biodiversity. We will secure Norfolk Island's 60 species of land snails via in situ and ex situ conservation with six key industry partners. The project expects to unite conservation actions ac ....Snails to the rescue! Conservation of Australia’s island invertebrates. This project aims to deliver an exemplar industry network model for conservation on Australia’s islands which are hotspots both of biodiversity and of extinctions. Protecting species on islands is therefore key to securing Australia’s biodiversity. We will secure Norfolk Island's 60 species of land snails via in situ and ex situ conservation with six key industry partners. The project expects to unite conservation actions across research, governments, and industry. Expected outcomes of this project include Norfolk Island emerging as a leader in global conservation. This should provide significant benefits such as a model for conservation that is applicable to thousands of isolated, range-restricted invertebrate species across Australia.Read moreRead less
Photography and Reconciliation: the Ngarrindjeri and the SA Museum. The project aims to recover, curate and exhibit a large archive of photographs of national significance created by Aboriginal photographers in the mid-20th century. Working with Ngarrindjeri custodians and the South Australian Museum, it expects to raise the status and diversity of Aboriginal voices in Australian visual culture and public life, undertaking a process of healing. Cultural revitalisation and generational learning v ....Photography and Reconciliation: the Ngarrindjeri and the SA Museum. The project aims to recover, curate and exhibit a large archive of photographs of national significance created by Aboriginal photographers in the mid-20th century. Working with Ngarrindjeri custodians and the South Australian Museum, it expects to raise the status and diversity of Aboriginal voices in Australian visual culture and public life, undertaking a process of healing. Cultural revitalisation and generational learning via the creation of a Living Archive and public exhibition are expected outcomes. Benefits include ensuring longevity of endangered heritage, broadening knowledge of southeastern Aboriginal lives and contributing new evidence to better understand the correlation between cultural revitalisation and community wellbeing.Read moreRead less