Nonlinear Time Series Analysis in Cardiac Physiology. We will develop innovative mathematically-based diagnostics with potentially significant savings in mortality and quality of life for affected individuals and health care costs to the community.
Cardiac diseases kill more Australians than any other disease group. According to the National Heart Foundation the prevalence to heart conditions increased by 18% over the last decade.
Medical practitioners are in need of reliable diagnostic too ....Nonlinear Time Series Analysis in Cardiac Physiology. We will develop innovative mathematically-based diagnostics with potentially significant savings in mortality and quality of life for affected individuals and health care costs to the community.
Cardiac diseases kill more Australians than any other disease group. According to the National Heart Foundation the prevalence to heart conditions increased by 18% over the last decade.
Medical practitioners are in need of reliable diagnostic tools to decide whether a person in front of them is at high risk from developing sudden cardiac death, and whether they should be fitted with an implant that could save their life.Read moreRead less
The effect of bans on short selling: a comprehensive study. Although the 2008 financial crisis has greatly impeded the global economy, it has provided a rare opportunity for researchers to verify the truthfulness of some assumptions made on financial markets that are running without liquidity problems. This project will develop a new option pricing theory suitable for financial markets under some short-selling restrictions. Through exploring, from both empirical and theoretical points of view, h ....The effect of bans on short selling: a comprehensive study. Although the 2008 financial crisis has greatly impeded the global economy, it has provided a rare opportunity for researchers to verify the truthfulness of some assumptions made on financial markets that are running without liquidity problems. This project will develop a new option pricing theory suitable for financial markets under some short-selling restrictions. Through exploring, from both empirical and theoretical points of view, how short-selling bans will affect some important assumptions made in conventional option pricing theory, the newly developed option pricing framework should not only assist in trading options, but also assist market regulators to effectively use bans on short selling to stabilise financial markets.Read moreRead less
Liquidity in financial markets. This project aims to develop a theory which models the effect of liquidity on option prices under different market conditions. Economic or financial crises are inevitable and affect economics. During or after a major financial crisis, market liquidity usually becomes risky and needs to be studied. Through both empirical and theoretical explorations, this project will quantify and measure liquidity risk and its effect on the options markets. It will develop a frame ....Liquidity in financial markets. This project aims to develop a theory which models the effect of liquidity on option prices under different market conditions. Economic or financial crises are inevitable and affect economics. During or after a major financial crisis, market liquidity usually becomes risky and needs to be studied. Through both empirical and theoretical explorations, this project will quantify and measure liquidity risk and its effect on the options markets. It will develop a framework to help market regulators manage illiquidity, enhance the efficiency of option trading in illiquid markets and help in the detection of market manipulation.Read moreRead less
Development of a Multi Threat Risk Assessment Model for Critical Infrastructure Using Scripted Agent Computer Technology. Current risk assessment paradigms are not suited to the control of catastrophic events such as terrorism. An advanced approach to risk assessment will be developed in this project for rare high impact events such as bomb blasts, where critical infrastructure is threatened. A new software platform based on scripted agent modelling will be constructed that will allow for state ....Development of a Multi Threat Risk Assessment Model for Critical Infrastructure Using Scripted Agent Computer Technology. Current risk assessment paradigms are not suited to the control of catastrophic events such as terrorism. An advanced approach to risk assessment will be developed in this project for rare high impact events such as bomb blasts, where critical infrastructure is threatened. A new software platform based on scripted agent modelling will be constructed that will allow for state of the art models to be used as agents providing a dynamic risk evaluation and necessary information for actions to infrastructure owners and emergency responders as a threat develops. Both the developed scripted agent and the risk assessment technologies can be applied to other technologies and complex risks, such as waste disposal and biotechnology.Read moreRead less
Development of a Multi Threat Risk Assessment Model for Critical Infrastructure Using Scripted Agent Computer Technology. The project will develop a distributed risk network capable of real time assessment of multiple threats to critical infrastructure, which will guide decision making on the appropriate response as the nature of the threat changes. This will assist all stakeholders and allow an integrated response across industry and government agencies. The developed technology will find read ....Development of a Multi Threat Risk Assessment Model for Critical Infrastructure Using Scripted Agent Computer Technology. The project will develop a distributed risk network capable of real time assessment of multiple threats to critical infrastructure, which will guide decision making on the appropriate response as the nature of the threat changes. This will assist all stakeholders and allow an integrated response across industry and government agencies. The developed technology will find ready application in other areas where integration of science and technology is required to solve complex problems. For example, risk network technology has application to natural hazards, waste disposal and financial markets while the scripted agent has application to communication technologies and sensor networks.Read moreRead less
Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or t ....Development of a multivariate physiologic state space analysis framework for characterising functional properties of the cardiovascular system. Pathologies of the cardiovascular system arising from heart diseases make a major contribution to morbidity and mortality in the Australian community. This project will provide new diagnostic modalities based on advanced noninvasive bioinstrumentation, signal processing and model-based analytical methods to identify early signs of developing disease or the acute exacerbation of existing disease. The impact of these new technologies on the early diagnosis and improved triaging of patients in emergency departments is potentially profound and could result in improved healthcare outcomes for the patients and reduced admissions to hospital as well as the development of a substantial international market.Read moreRead less
Dynamics of atherosclerotic plaque formation, growth and regression. This project aims to provide a mathematical framework to interpret plaque growth. Many biological processes contribute to the growth of atherosclerotic plaques inside arteries. Lipoproteins enter the artery walls and stimulate tissues to signal to cells which duly respond so that fatty streaks form and grow into dangerous plaques that cause heart attacks or stroke. These processes are often nonlinear and operate on widely varyi ....Dynamics of atherosclerotic plaque formation, growth and regression. This project aims to provide a mathematical framework to interpret plaque growth. Many biological processes contribute to the growth of atherosclerotic plaques inside arteries. Lipoproteins enter the artery walls and stimulate tissues to signal to cells which duly respond so that fatty streaks form and grow into dangerous plaques that cause heart attacks or stroke. These processes are often nonlinear and operate on widely varying time scales. The project plans to use systems of ordinary differential equations, partial differential equations with non-standard boundary conditions, and bifurcation theory to find how nonlinear processes shape plaque growth. The expected results may demonstrate the importance of bifurcations, dynamics and nonlinear systems in plaque growth and provide new models to interpret biological data.Read moreRead less