Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100050
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
Spacecraft Innovation Laboratory. The Australian Spacecraft Innovation Laboratory is designed to provide researchers and entrepreneurs with a venue to integrate and test their “cubesats”, satellites the size of a loaf of bread, and small payloads. By centralising the satellite integration function, the standard of Australian space assets can be assured, giving researchers confidence that their spacebased experiments will succeed. Knowledge transfer to space start-ups will be accelerated by easin ....Spacecraft Innovation Laboratory. The Australian Spacecraft Innovation Laboratory is designed to provide researchers and entrepreneurs with a venue to integrate and test their “cubesats”, satellites the size of a loaf of bread, and small payloads. By centralising the satellite integration function, the standard of Australian space assets can be assured, giving researchers confidence that their spacebased experiments will succeed. Knowledge transfer to space start-ups will be accelerated by easing their access to space.
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Learning Software Security Analysers with Imperfect Data. This project aims to systematically investigate next-generation learning-based software security analysis to detect vulnerabilities in real-world large-scale software. The expected learning-based foundation will support the handling of imperfect data in order to provide a precise, scalable and adaptive security analysis of the critical software components, thus capturing important security vulnerabilities missed by existing approaches. Th ....Learning Software Security Analysers with Imperfect Data. This project aims to systematically investigate next-generation learning-based software security analysis to detect vulnerabilities in real-world large-scale software. The expected learning-based foundation will support the handling of imperfect data in order to provide a precise, scalable and adaptive security analysis of the critical software components, thus capturing important security vulnerabilities missed by existing approaches. The success of this project will further enhance the international competitiveness of Australian research in this important field and will benefit any Australian industry and business where software systems are deeply-rooted, such as transportation, smart homes, medical devices, defence and finance.Read moreRead less
Non-equilibrium reacting shock layers. This project aims is to study the non-equilibrium aerodynamic processes involved in hypervelocity flight. The design of vehicles for high speed flight is critically dependent on modelling the interactions between the flow field and the airframe, and the current lack of understanding is restricting the scope and benefit of viable activities in space. The expected outcomes include the ability to design optimised heat shields and air-frames with minimum mass a ....Non-equilibrium reacting shock layers. This project aims is to study the non-equilibrium aerodynamic processes involved in hypervelocity flight. The design of vehicles for high speed flight is critically dependent on modelling the interactions between the flow field and the airframe, and the current lack of understanding is restricting the scope and benefit of viable activities in space. The expected outcomes include the ability to design optimised heat shields and air-frames with minimum mass and maximum payload, precisely targeting specific flight conditions and vehicle shapes. The prospective benefits include increased productivity and reliability and reduced cost of missions to and from space, and a proliferation of new applications which this understanding will facilitate.Read moreRead less
Industrial Transformation Training Centres - Grant ID: IC170100023
Funder
Australian Research Council
Funding Amount
$4,619,950.00
Summary
ARC Training Centre for Cubesats, Uncrewed Aerial Vehicles, and Their Applications. The ARC Training Centre for CubeSats, Unmanned Aerial Vehicles and their Applications aims to train the next generation of workers in cutting edge advanced manufacturing, entrepreneurship, and commercial space and unmanned aerial vehicle applications. The Australian economy, security, and society increasingly rely on access to space for vital data and services, and a skilled workforce is required to grow the sec ....ARC Training Centre for Cubesats, Uncrewed Aerial Vehicles, and Their Applications. The ARC Training Centre for CubeSats, Unmanned Aerial Vehicles and their Applications aims to train the next generation of workers in cutting edge advanced manufacturing, entrepreneurship, and commercial space and unmanned aerial vehicle applications. The Australian economy, security, and society increasingly rely on access to space for vital data and services, and a skilled workforce is required to grow the sector and capitalise on global opportunities. Of great commercial value, with very low costs, CubeSats are a new class of small satellites, which with UAVs are disrupting the international satellite market. The expected outcome of this Training Centre is to develop new instruments, technology and products to solve crucial problems, and develop a world-class Australian industry in CubeSats, unmanned aerial vehicles, and related products.Read moreRead less
Nuclear and chromatin architecture in the replication stress response. DNA replication is an essential biological activity required for the transmittance of genomic material across cell divisions. If errors occur during DNA replication, this results in dangerous outcomes including mutation, genome instability, and cell death. Cells cope with challenges to DNA replication through a process called the replication stress response. This fellowship explores a newly discovered pathway in the replicati ....Nuclear and chromatin architecture in the replication stress response. DNA replication is an essential biological activity required for the transmittance of genomic material across cell divisions. If errors occur during DNA replication, this results in dangerous outcomes including mutation, genome instability, and cell death. Cells cope with challenges to DNA replication through a process called the replication stress response. This fellowship explores a newly discovered pathway in the replication stress response where changes to the architecture of a cell nucleus, and movement of the genomic material inside, promotes repair of genomic damage that occurs during replication. The result of this project will be an understanding of fundamental biological processes that protect human genomes.Read moreRead less
How do cells survive nutrient stress? Insight into mechanisms. This project studies cell survival under nutrient stress in eukaryotes. Building on extensive preliminary data that identifies novel TOR (Target of Rapamycin) Complex 2 (TORC2) control points it expects to generate new knowledge of critical and conserved features of stress control of macroautophagy that ensures cell survival. It uses interdisciplinary and innovative approaches to validate and characterize nutrient-stress dependent si ....How do cells survive nutrient stress? Insight into mechanisms. This project studies cell survival under nutrient stress in eukaryotes. Building on extensive preliminary data that identifies novel TOR (Target of Rapamycin) Complex 2 (TORC2) control points it expects to generate new knowledge of critical and conserved features of stress control of macroautophagy that ensures cell survival. It uses interdisciplinary and innovative approaches to validate and characterize nutrient-stress dependent signaling. Expected outcomes include novel insights into environmental control of cell proliferation and forging cross institutional collaborations. This knowledge benefits basic and applied biology and is relevant to industries/projects utilizing living cells as nutrient supports cell survival and proliferation.Read moreRead less
Navigating flux control through a branched metabolic pathway. This project aims to uncover control points and programmes in the mevalonate pathway, an important cellular metabolic pathway that produces cholesterol and isoprenoids. Knowledge of its regulation is largely restricted to just one enzyme (HMGCR). This project will determine how regulation of the later sterol-producing segment affects the early isoprenoid-segment of the mevalonate pathway; investigate how the two alternate routes to ch ....Navigating flux control through a branched metabolic pathway. This project aims to uncover control points and programmes in the mevalonate pathway, an important cellular metabolic pathway that produces cholesterol and isoprenoids. Knowledge of its regulation is largely restricted to just one enzyme (HMGCR). This project will determine how regulation of the later sterol-producing segment affects the early isoprenoid-segment of the mevalonate pathway; investigate how the two alternate routes to cholesterol synthesis operate and are regulated; and explore a co-ordinated and possibly co-operative transcriptional program. This project is expected to provide valuable knowledge of how cells control these critical lipids, which will ultimately inform better ways to treat diseases of cholesterol excess and defects in this pathway.Read moreRead less
Molecular mechanisms determining the lipid composition of synapses. Synapses between neurons play a key role in all functions of the nervous system including learning and memory. They are mostly composed of the unique combination of proteins and lipids, which function together to enable neurotransmission. While the molecular mechanisms determining the protein composition of synapses are well characterised, the mechanisms defining the lipid composition of synapses remain unknown. The project will ....Molecular mechanisms determining the lipid composition of synapses. Synapses between neurons play a key role in all functions of the nervous system including learning and memory. They are mostly composed of the unique combination of proteins and lipids, which function together to enable neurotransmission. While the molecular mechanisms determining the protein composition of synapses are well characterised, the mechanisms defining the lipid composition of synapses remain unknown. The project will use advanced techniques of neuroscience and lipid research to determine the mechanisms of lipid transport and retention at synapses. The project is expected to generate new knowledge about the fundamental mechanisms of brain function, which will be useful for developing new therapeutics enhancing the brain power.Read moreRead less