Alpha-particles linked to recombinant antibodies targeting tumour cells have potential to effectively treat tumours while minimising normal tissue side effects. We will explore a novel alpha-particle therapy approach to solid tumours, by delivering 225Ac directly into tumour cells, or into cells that support the tumour (microenvironment). This approach will hopefully result in development of a new approach to treatment of cancers that are resistant to conventional therapies.
Towards a high density silicon phase change memory device. This project builds upon our exciting recent findings that amorphous silicon can be transformed to a conducting crystalline phase following small-scale indentation. Furthermore the process is reversible as re-indentation can induce a transformation back to insulating amorphous silicon. This process appears to occur in extremely small (nanoscale) volumes of silicon. We plan to explore the viability of exploiting this behaviour to develo ....Towards a high density silicon phase change memory device. This project builds upon our exciting recent findings that amorphous silicon can be transformed to a conducting crystalline phase following small-scale indentation. Furthermore the process is reversible as re-indentation can induce a transformation back to insulating amorphous silicon. This process appears to occur in extremely small (nanoscale) volumes of silicon. We plan to explore the viability of exploiting this behaviour to develop an entirely new information storage system: a high-density silicon phase change memory. This project aims to study small-scale transformation behaviour in silicon and to design demonstrator memory devices based on both micro-electromechanical systems and solid state technologies.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0668421
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
A MEG-based cognitive neuroscience laboratory. At present there is no MEG system in Australia, whereas MEG systems are currently springing up in research institutions in many other countries across the globe. This project will enable Australia to remain at the forefront of research in the cognitive neurosciences, as well as provide training opportunities to Australian doctoral students and postdoctoral fellows in the use of MEG in research. Finally, the MEG laboratory will allow Australian resea ....A MEG-based cognitive neuroscience laboratory. At present there is no MEG system in Australia, whereas MEG systems are currently springing up in research institutions in many other countries across the globe. This project will enable Australia to remain at the forefront of research in the cognitive neurosciences, as well as provide training opportunities to Australian doctoral students and postdoctoral fellows in the use of MEG in research. Finally, the MEG laboratory will allow Australian researchers to fill important gaps in our understanding of several areas of cognitive neuroscience, including basic auditory and visual processing, the study of cognitive processing in schizophrenia and in children with dyslexia and/or specific language impairment.Read moreRead less
Towards efficient real-time generation of detectable musical macrostructure. Efficient generation of detectable large scale musical structure is needed for commercial audiovisual applications, and for creative music making. But computer mediation of music has focused elsewhere: on sound synthesis and sequencing, editing, mixing and notation. I will apply computational processes like the handling of chunks of genetic information in evolution, to generate large scale musical structure. I will con ....Towards efficient real-time generation of detectable musical macrostructure. Efficient generation of detectable large scale musical structure is needed for commercial audiovisual applications, and for creative music making. But computer mediation of music has focused elsewhere: on sound synthesis and sequencing, editing, mixing and notation. I will apply computational processes like the handling of chunks of genetic information in evolution, to generate large scale musical structure. I will control segmentation; framing of internal segments; spatialisation; and the overlaying of separable musical streams. Expert cognitive assessment of the resultant structures will be investigated, and theories of segmentation, streaming and their relationships with expression and affect developed and tested.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100004
Funder
Australian Research Council
Funding Amount
$762,800.00
Summary
Ultrafast Infrared Spectroscopy Facility. The Ultrafast Infrared Spectroscopy Facility will provide a suite of techniques spanning the visible to mid-infrared spectral regions, on time scales corresponding to the emission of light, and energy conversion in low energy advanced functional materials. Research performed with this equipment will include photonic and thermal energy conversion; nanophotonics; quantum technologies and new infrared functional materials. This facility will enhance capacit ....Ultrafast Infrared Spectroscopy Facility. The Ultrafast Infrared Spectroscopy Facility will provide a suite of techniques spanning the visible to mid-infrared spectral regions, on time scales corresponding to the emission of light, and energy conversion in low energy advanced functional materials. Research performed with this equipment will include photonic and thermal energy conversion; nanophotonics; quantum technologies and new infrared functional materials. This facility will enhance capacity in probing new materials and devices in the near and mid-infrared regions, and will increase institutional and cross-disciplinary research collaboration.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE160101368
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Silicon 2.0: The nature of grown-in defects in very high-purity silicon. This project aims to produce technologies to maximise the electronic quality of silicon and mitigate the negative impacts of defects on high-efficiency solar cells. The intended outcomes are the development of novel solar cell processes to produce defect-free silicon and new characterisation techniques to image defects in silicon wafers. This would allow high efficiency solar cells to overcome their current limits and unloc ....Silicon 2.0: The nature of grown-in defects in very high-purity silicon. This project aims to produce technologies to maximise the electronic quality of silicon and mitigate the negative impacts of defects on high-efficiency solar cells. The intended outcomes are the development of novel solar cell processes to produce defect-free silicon and new characterisation techniques to image defects in silicon wafers. This would allow high efficiency solar cells to overcome their current limits and unlock the potential of current processes to produce solar cells with efficiency above 26 per cent, providing more efficient and affordable solar electricity.Read moreRead less
A longitudinal study of the interaction of home and school language in three Aboriginal communities. The importance of language skills cannot be underestimated, and contribute to 'a healthy start to life'. In multilingual Indigenous communities, children must negotiate the complexities of different languages used for different purposes. This project will provide detailed insights into how children manage differences between home and school language, the kinds of problems they encounter when the ....A longitudinal study of the interaction of home and school language in three Aboriginal communities. The importance of language skills cannot be underestimated, and contribute to 'a healthy start to life'. In multilingual Indigenous communities, children must negotiate the complexities of different languages used for different purposes. This project will provide detailed insights into how children manage differences between home and school language, the kinds of problems they encounter when they enter the school system, and how their languages develop over the first four crucial years of school which provide the foundation for the children's future education. Their ability to manage the language of school underpins their ability to lead successful and engaged lives as adults. Read moreRead less
Nanophotonics for strong absorption in extremely thin solar cells: moving beyond silicon. This project will lead to the development of extremely thin solar cells made of novel low-cost materials, which would likely reduce the cost of photovoltaic technology. If the cost of photovoltaics was sufficiently low then it could have a major impact on reducing greenhouse gas emissions and pollution in Australia and worldwide.
Doped metal perovskites for electrocatalysis. This project aims to discover and design perovskite metal-oxide electrocatalyst materials and develop electrocatalytic methods for efficiently driving the oxygen evolution reaction and the oxygen reduction reaction. These are the two most crucial reactions in sustainable energy cycles involving water, hydrogen and oxygen. The project’s anticipated advances in electrocatalysis efficiency for these two reactions will benefit sustainable energy technolo ....Doped metal perovskites for electrocatalysis. This project aims to discover and design perovskite metal-oxide electrocatalyst materials and develop electrocatalytic methods for efficiently driving the oxygen evolution reaction and the oxygen reduction reaction. These are the two most crucial reactions in sustainable energy cycles involving water, hydrogen and oxygen. The project’s anticipated advances in electrocatalysis efficiency for these two reactions will benefit sustainable energy technologies such as fuel cells, metal air batteries and water splitting.Read moreRead less