Discovery Early Career Researcher Award - Grant ID: DE230101105
Funder
Australian Research Council
Funding Amount
$422,318.00
Summary
Developing Polymer Electrolytes for Operational All-Solid-State Batteries. This project aims to advance the development of safe rechargeable all-solid-state batteries (ASSBs) by innovating fluorinated block copolymers as solid-state electrolytes. ASSBs are the most promising power source for emerging energy storage goals, however, low ionic conductivity and poor long-term cycling stability are critical bottlenecks to their successful application. This project seeks to tackle these challenges by ....Developing Polymer Electrolytes for Operational All-Solid-State Batteries. This project aims to advance the development of safe rechargeable all-solid-state batteries (ASSBs) by innovating fluorinated block copolymers as solid-state electrolytes. ASSBs are the most promising power source for emerging energy storage goals, however, low ionic conductivity and poor long-term cycling stability are critical bottlenecks to their successful application. This project seeks to tackle these challenges by fabricating unique ionic conduction channels and stabilising electrode-electrolyte interfaces using fluorinated block copolymer electrolytes. The expected outcomes are new knowledge in polymer electrolytes and advancement in the commercialisation of ASSBs toward more efficient, safe and reliable energy storage technologies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE220101190
Funder
Australian Research Council
Funding Amount
$418,292.00
Summary
Designing low-toxicity and stable perovskites for solar energy conversion. Efficient solar energy conversion systems can significantly promote sustainable and low carbon-emission economy. This project aims to rationally design low-toxic and stable metal halide perovskites for efficient solar hydrogen conversion. The key concept is to design stable lead-free metal halide perovskite semiconductors with superior photophysical properties for solar-driven valuable chemical production. Expected outcom ....Designing low-toxicity and stable perovskites for solar energy conversion. Efficient solar energy conversion systems can significantly promote sustainable and low carbon-emission economy. This project aims to rationally design low-toxic and stable metal halide perovskites for efficient solar hydrogen conversion. The key concept is to design stable lead-free metal halide perovskite semiconductors with superior photophysical properties for solar-driven valuable chemical production. Expected outcomes include new generation advanced materials and proof-of-concept technologies for efficient solar hydrogen generation. The successful completion of this project will benefit Australia by positioning the nation at the frontier of advanced functional materials and renewable energy supply technologies.Read moreRead less
Perovskite Quantum Dots for Solar Hydrogen Generation. Sustainable hydrogen production is highly significant towards decarbonised economy. This project aims to develop new classes of organometal halide perovskite quantum dots (OHPQDs) for efficient photoelecrochemical hydrogen production. The key concept is to design toxic Lead free/less OHPQDs for use as stable photoelectrode materials in self-powered sunlight driven water splitting devices. Expected outcomes include new generation advanced mat ....Perovskite Quantum Dots for Solar Hydrogen Generation. Sustainable hydrogen production is highly significant towards decarbonised economy. This project aims to develop new classes of organometal halide perovskite quantum dots (OHPQDs) for efficient photoelecrochemical hydrogen production. The key concept is to design toxic Lead free/less OHPQDs for use as stable photoelectrode materials in self-powered sunlight driven water splitting devices. Expected outcomes include new generation advanced materials and revolutionary technologies for efficient solar hydrogen generation. The successful completion of this project will significantly benefit Australia by positioning the nation at the frontier of renewable hydrogen supply technologies. Read moreRead less
Design of new two-dimensional materials for lithium sulphur batteries. Design of new two-dimensional materials for lithium sulphur batteries. This project aims to develop classes of electrode material systems for high performance batteries. This project will design new hierarchical cathode composites for a high capacity lithium-sulphur battery with a long cycling life. It intends to improve energy density by confining active sulphur in conductive graphene and exfoliated titanium dioxide nanoshee ....Design of new two-dimensional materials for lithium sulphur batteries. Design of new two-dimensional materials for lithium sulphur batteries. This project aims to develop classes of electrode material systems for high performance batteries. This project will design new hierarchical cathode composites for a high capacity lithium-sulphur battery with a long cycling life. It intends to improve energy density by confining active sulphur in conductive graphene and exfoliated titanium dioxide nanosheets, and use a unique hybrid protecting layer to suppress cycling instability. This research is expected to establish the relationship between synthetic conditions, structure, and electrochemical performance.Read moreRead less
Role of Tau and Synapsin in clustering distinct synaptic vesicle pools. Neurotransmitter-containing synaptic vesicles (SVs) are highly enriched in specific locations of brain cells, called nerve terminals via an unknown mechanism. The clustering of SVs depend on the phosphorylation of an unknown set of proteins. Two key proteins have been identified for their phosphorylation pattern and their potential to form membraneless compartments: tau and synapsin. Using highly innovative single-molecule s ....Role of Tau and Synapsin in clustering distinct synaptic vesicle pools. Neurotransmitter-containing synaptic vesicles (SVs) are highly enriched in specific locations of brain cells, called nerve terminals via an unknown mechanism. The clustering of SVs depend on the phosphorylation of an unknown set of proteins. Two key proteins have been identified for their phosphorylation pattern and their potential to form membraneless compartments: tau and synapsin. Using highly innovative single-molecule super-resolution microscopy, this grant will uncover how tau and synapsin phosphorylation controls the clustering of SVs thereby regulating neurotransmitter release. This project uses improved nanoscopic technologies and international
collaborations to unveil novel avenues in our understanding of brain communication.Read moreRead less
Super-resolving neurotransmitter release machinery during priming. Understanding how neurons communicate in the brain is one of the most challenging feats in neuroscience. The assembly of the molecular machinery involved in communication is unknown. This grant aims to understand how priming molecules Munc18 and Munc13, undergo a series of molecular steps leading to the release of neurotransmitter. Using innovative single-molecule super-resolution imaging we will uncover how Munc18 and Munc13 are ....Super-resolving neurotransmitter release machinery during priming. Understanding how neurons communicate in the brain is one of the most challenging feats in neuroscience. The assembly of the molecular machinery involved in communication is unknown. This grant aims to understand how priming molecules Munc18 and Munc13, undergo a series of molecular steps leading to the release of neurotransmitter. Using innovative single-molecule super-resolution imaging we will uncover how Munc18 and Munc13 are spatially and temporally organised to mediate communication. By elucidating how nanoclustering of these essential proteins enables key steps, this grant will reveal how brain cells communicate. This may then provide new opportunities to optimise underlying functions such as cognition, sensory and motor processing.Read moreRead less
Click chemistry to reveal how neurons and glia shape perineuronal nets . The extracellular matrix (ECM) and its perineuronal nets (which are net-like structures with holes wrapped around neurons) are largely underexplored, despite representing a remarkable 20% of the brain’s total volume and having been suggested to be involved in many brain functions. Interestingly, digestion of the ECM improves learning and memory, but deficits return once the ECM has reformed. However, how this ECM remodellin ....Click chemistry to reveal how neurons and glia shape perineuronal nets . The extracellular matrix (ECM) and its perineuronal nets (which are net-like structures with holes wrapped around neurons) are largely underexplored, despite representing a remarkable 20% of the brain’s total volume and having been suggested to be involved in many brain functions. Interestingly, digestion of the ECM improves learning and memory, but deficits return once the ECM has reformed. However, how this ECM remodelling is organised at a cell-type level is not understood. Here we aim to close this knowledge gap, using cutting-edge technology including bioconjugation and ultrasound-mediated cargo delivery. Together, this project aims to contribute to a deeper understanding of this major brain compartment in neuronal function. Read moreRead less
Productivity, growth and unemployment in economies with frictions. This project aims to examine decisions driving productivity, growth, and unemployment in macroeconomies with frictions. It examines how government (fiscal, monetary, and education) policies determine these decisions, and identifies the best configurations of these policies. It will construct dynamic general equilibrium models of economies to analyse the causal structure behind productivity changes, growth and unemployment. It wil ....Productivity, growth and unemployment in economies with frictions. This project aims to examine decisions driving productivity, growth, and unemployment in macroeconomies with frictions. It examines how government (fiscal, monetary, and education) policies determine these decisions, and identifies the best configurations of these policies. It will construct dynamic general equilibrium models of economies to analyse the causal structure behind productivity changes, growth and unemployment. It will conduct quantitative experiments using simulations, to estimate optimal government policy design settings. This project expects to identify policies that promote productivity, growth and employment.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE240100561
Funder
Australian Research Council
Funding Amount
$462,237.00
Summary
Understanding how platelets mediate new neuron formation in the adult brain. Exercise boosts the generation of new nerve cells from adult neural stem cells in the part of the brain responsible for learning and memory, the hippocampus. This project aims to investigate the mechanisms behind this effect, in particular, how blood cells known as platelets mediate this process. The expected outcomes include the discovery of new communication pathways between platelets and the brain following exercise ....Understanding how platelets mediate new neuron formation in the adult brain. Exercise boosts the generation of new nerve cells from adult neural stem cells in the part of the brain responsible for learning and memory, the hippocampus. This project aims to investigate the mechanisms behind this effect, in particular, how blood cells known as platelets mediate this process. The expected outcomes include the discovery of new communication pathways between platelets and the brain following exercise and will determine the importance of these blood cells in mediating brain function. This will help to explain how exercise affects the brain and may benefit Australian society through the implementation of new methods to support learning and memory in schools and workplaces, thereby enhancing performance and productivity.Read moreRead less