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Research Topic : CELL SURFACE
Australian State/Territory : VIC
Australian State/Territory : ACT
Socio-Economic Objective : Other
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  • Funded Activity

    Linkage Projects - Grant ID: LP0455015

    Funder
    Australian Research Council
    Funding Amount
    $365,000.00
    Summary
    Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas. X-ray and neutron scattering techniques, de .... Designer Surfactants for Creation of Emulsion Properties. We propose new approaches to the design of surfactants for stabilising water in oil emulsions. New block copolymer surfactants may be "tailored" for head group structure and a pre-chosen hydrophilic/lipophilic balance at the oil-water interface using the Australian developed RAFT polymer synthesis method and polymeric inorganic species. The proposers have an extensive background in these areas. X-ray and neutron scattering techniques, developed by us, allow the interfacial structure of the surfactant to be found and the intellectual "loop" closed in the design process. Preliminary screening will be done using the surface balance and bulk emulsion synthesis.
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    Funded Activity

    Linkage Projects - Grant ID: LP0210146

    Funder
    Australian Research Council
    Funding Amount
    $340,000.00
    Summary
    High Internal Phase Emulsions - Structure and Rheology Control. Our first SPIRT Grant with ORICA Australia Ltd has successfully identified nanostructures in high internal phase emulsions which confer useful stability and robustness on these industrially important systems. The aim now is to ramify those discoveries both scientifically and technologically in the design of emulsion structure using our, now established, techniques. In particular, the objective is to control both nanoscale and mes .... High Internal Phase Emulsions - Structure and Rheology Control. Our first SPIRT Grant with ORICA Australia Ltd has successfully identified nanostructures in high internal phase emulsions which confer useful stability and robustness on these industrially important systems. The aim now is to ramify those discoveries both scientifically and technologically in the design of emulsion structure using our, now established, techniques. In particular, the objective is to control both nanoscale and mesoscale structure in emulsion formulation, as well as the rheology and stability of emulsion preparations. To do this we plan to use mixed surfactant systems and to study intersurfactant synergic effects on the structure and fluidity of the interfacial material. We believe that the proposed work is unique and that the outcomes will be scientifically novel and also valuable for Australian industry.
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    Funded Activity

    Linkage Projects - Grant ID: LP0347461

    Funder
    Australian Research Council
    Funding Amount
    $345,000.00
    Summary
    Why is the photosynthetic CO2-fixing enzyme, Rubisco, so inefficient? Dissection of the catalytic chemistry by computational simulation and experimental testing. Fixation of CO2 by the enzyme Rubisco during photosynthesis produces organic compounds which feed all life. Despite this critical role, Rubisco catalyses its reaction sluggishly and, worse, discriminates poorly between CO2 and O2, leading to useless products. Our combined expertise equips us to analyse Rubisco's mechanism using quantum- .... Why is the photosynthetic CO2-fixing enzyme, Rubisco, so inefficient? Dissection of the catalytic chemistry by computational simulation and experimental testing. Fixation of CO2 by the enzyme Rubisco during photosynthesis produces organic compounds which feed all life. Despite this critical role, Rubisco catalyses its reaction sluggishly and, worse, discriminates poorly between CO2 and O2, leading to useless products. Our combined expertise equips us to analyse Rubisco's mechanism using quantum-chemical methods and then test predictions experimentally. We will capitalise on our previous successful studies of Rubisco by addressing emergent issues which are the keys to understanding catalytic efficiency and CO2/O2 selectivity: the roles of a carbamylated lysine; the way CO2 addition is rendered irreversible; and the spin inversion inherent in O2 addition.
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    Funded Activity

    Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989920

    Funder
    Australian Research Council
    Funding Amount
    $750,000.00
    Summary
    Microbial and Cellular Imaging and Analysis Facility. The Microbial and Cellular Imaging and Analysis Facility will rapidly establish itself as one of Australia's premier science facilities. It will provide the capacity to investigate the structure and molecular dynamics of viruses and microbial, human, animal and plant cells with unprecedented high resolution in both pure and applied research settings, guided by Australia's leading experts in many research strengths. This facility addresses a c .... Microbial and Cellular Imaging and Analysis Facility. The Microbial and Cellular Imaging and Analysis Facility will rapidly establish itself as one of Australia's premier science facilities. It will provide the capacity to investigate the structure and molecular dynamics of viruses and microbial, human, animal and plant cells with unprecedented high resolution in both pure and applied research settings, guided by Australia's leading experts in many research strengths. This facility addresses a current unmet need for scientists in this country and will provide cutting-edge technologies to Australian researchers so they can better detect, understand, and treat human, animal and plant diseases and the environmental impact of climate change.
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    Showing 1-4 of 4 Funded Activites

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