Scalable Visual Analytics for Uncertain Dynamic Networks. Technological advances have provided a data deluge over the past few years, and have led to many large uncertain and dynamic network models. This includes terrorist networks, marketing networks, facebook networks, various biological networks, and software engineering structures. Human understanding of such networks is difficult. This project aims to provide new methods for visual analysis of large uncertain dynamic networks such as these. ....Scalable Visual Analytics for Uncertain Dynamic Networks. Technological advances have provided a data deluge over the past few years, and have led to many large uncertain and dynamic network models. This includes terrorist networks, marketing networks, facebook networks, various biological networks, and software engineering structures. Human understanding of such networks is difficult. This project aims to provide new methods for visual analysis of large uncertain dynamic networks such as these. The algorithms developed in the project will help security analysts to monitor illegal behaviour such as money laundering and terrorist activities, help biologists understand key biological systems, and help engineers to understand large software systems.Read moreRead less
The Immunoregulatory Role of the Endogenous Cannabinoid Anandamide. Anandamides are naturally occurring fatty acids that act at the cannabinoid receptor expressed in the brain and periphery. A new proposal by our research group challenges traditional models of the disease process by suggesting that the anandamide system is an important imunoregulatory system that can be targeted by invading pathogens. We propose that disruption to the anandamide system, by bacteria or viruses acting at the rece ....The Immunoregulatory Role of the Endogenous Cannabinoid Anandamide. Anandamides are naturally occurring fatty acids that act at the cannabinoid receptor expressed in the brain and periphery. A new proposal by our research group challenges traditional models of the disease process by suggesting that the anandamide system is an important imunoregulatory system that can be targeted by invading pathogens. We propose that disruption to the anandamide system, by bacteria or viruses acting at the receptor to block immunological responses, contributes to chronic illness states. At this point we have good evidence that anandamides are immunoregulators, however, we have very little knowledge of their precise physiological role. The aim of this research is to begin to characterise the immunoregulatory role of the anandamide system. This project will provide a comprehensive understanding of this endogenous control system, the immunological properties of which have not previously been described. The outcome of this research may lead to the identification of new avenues for the development of pharmaceutical interventions that can target this system.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130101591
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Novel postsynaptic functions of the microtubule-associated protein tau. The protein tau is present in abnormal deposits in brains of individuals with dementia. The main aim of this project is to unravel and understand in detail new roles of tau in neurons and thus shed new light into normal brain function. Understanding these new functions of tau will aid in identifying new ways to treat these debilitating diseases.
Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100092
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Fluorescence microscopy with optical tweezers: imaging cellular responses. Life relies on the ability of our cells to receive and respond to signals with pinpoint accuracy, involving both chemical and mechanical signals. This equipment will allow scientists to expose cells to both types of signals and measure the response at an unprecedented level of accuracy for the first time.
Discovery Early Career Researcher Award - Grant ID: DE180101416
Funder
Australian Research Council
Funding Amount
$338,446.00
Summary
Broadening horizons: using curiosity to diversify behaviour. This project aims to explore how interactive systems can encourage their users to try new things. This is made possible by recent developments in artificial intelligence that can estimate what will make users curious. This project expects to generate new knowledge about how interactive technology can encourage diverse behaviour by stimulating curiosity. Expected outcomes include a framework for how to design interactive systems that en ....Broadening horizons: using curiosity to diversify behaviour. This project aims to explore how interactive systems can encourage their users to try new things. This is made possible by recent developments in artificial intelligence that can estimate what will make users curious. This project expects to generate new knowledge about how interactive technology can encourage diverse behaviour by stimulating curiosity. Expected outcomes include a framework for how to design interactive systems that encourage users to try new things, and a greater theoretical understanding of how to diversify user behaviour.Read moreRead less
Using 3D printing to improve access to graphics by vision-impaired people. This project aims to investigate the possible benefits of 3D printing for production of accessible materials for vision-impaired people. Currently tactile graphics are used to provide severely vision-impaired adults and children with access to graphical content used in education and in orientation and mobility training. This project is expected to clarify the kinds of graphics for which 3D prints are better suited than ta ....Using 3D printing to improve access to graphics by vision-impaired people. This project aims to investigate the possible benefits of 3D printing for production of accessible materials for vision-impaired people. Currently tactile graphics are used to provide severely vision-impaired adults and children with access to graphical content used in education and in orientation and mobility training. This project is expected to clarify the kinds of graphics for which 3D prints are better suited than tactile graphics, and to build capacity within the national accessible format provision sector for the production and use of 3D prints. Benefits will include increased educational opportunities and quality of life for Australians with severe vision impairment, through improved access to graphic materials used in education and orientation and mobility training.
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Integrating human operators into large-scale sensor networks. Information awareness is critical in many applications of national importance: from bush fire fighting and defence to transportation and health care. These applications involve tasks in which timely delivery and fusion of heterogeneous information streams is of critical importance. They can all benefit from the use of robotic and embedded sensor networks considered in this project. Human operators, acting as users or supervisors, will ....Integrating human operators into large-scale sensor networks. Information awareness is critical in many applications of national importance: from bush fire fighting and defence to transportation and health care. These applications involve tasks in which timely delivery and fusion of heterogeneous information streams is of critical importance. They can all benefit from the use of robotic and embedded sensor networks considered in this project. Human operators, acting as users or supervisors, will remain at the centre of these systems. The technology and algorithms developed in this project will efficiently structure information exchange between humans and sensor networks. Establishing Australian leadership in this fast-evolving high-technology field will spur growth and job creation.Read moreRead less
Gesture-controlled interaction to enrich information access. This project is a study of gestural computing (enabled by sensors such as pressure mats, infra-red sensors and video tracking) which aims to move away from desk-bound, restrictive computing environments and towards computing that is more integral to the building structure and space itself. Linking gesture controllers and information sonification delivers a unique bridge between data and human interaction. Enriching the capacity to acce ....Gesture-controlled interaction to enrich information access. This project is a study of gestural computing (enabled by sensors such as pressure mats, infra-red sensors and video tracking) which aims to move away from desk-bound, restrictive computing environments and towards computing that is more integral to the building structure and space itself. Linking gesture controllers and information sonification delivers a unique bridge between data and human interaction. Enriching the capacity to access information in dense workplace environments is central to improved efficiency across the Australian workforce. Greater accuracy and enhanced techniques for controlling information in visually-overloaded work environments contribute to Australia's competitive leadership in a global marketplace.Read moreRead less