Development of new interventions and treatment for schistosomiasis morbidity control. Australia has played a lead role in Parasitology research. It is vital to remain at the forefront in combating the human and livestock diseases that parasites cause. Vaccine assessment and the large scale analysis of patient tissues are vital to the biotechnology, agriculture and pharmaceutical industries with outcomes leading to innovative strategies for control. Politically there is value as it is altruistic ....Development of new interventions and treatment for schistosomiasis morbidity control. Australia has played a lead role in Parasitology research. It is vital to remain at the forefront in combating the human and livestock diseases that parasites cause. Vaccine assessment and the large scale analysis of patient tissues are vital to the biotechnology, agriculture and pharmaceutical industries with outcomes leading to innovative strategies for control. Politically there is value as it is altruistic to develop new tools, technologies and treatments for the Asia/Pacific region. Economically, Australia will have first pass at developing the intellectual property arising. As well, the therapies would be developed locally to the benefit of Australia's human therapeutics industry and bio-reagent manufacturers.Read moreRead less
Dissecting the shared genetic architecture of psychiatric and psychological traits with application to prediction of genetic risk. Identification of the early phase of psychiatric disorders is considered critical for early intervention which is the essence of prevention. At present, the main obstacle to targeted early intervention strategies in psychiatric disorders is the non-specific nature of early stage symptoms. Many psychiatric disorders present with symptoms of depressed mood and anxiety ....Dissecting the shared genetic architecture of psychiatric and psychological traits with application to prediction of genetic risk. Identification of the early phase of psychiatric disorders is considered critical for early intervention which is the essence of prevention. At present, the main obstacle to targeted early intervention strategies in psychiatric disorders is the non-specific nature of early stage symptoms. Many psychiatric disorders present with symptoms of depressed mood and anxiety in the early stages, yet best intervention treatments are dependent on the final (unknown) diagnosed disorder. Prediction of genetic risk is likely to make an important contribution for identification of individuals at risk of specific psychiatric disorders so that the best early intervention treatment can be administered. Read moreRead less
Changing the lives of young Australians with emotional disorders using a simple three-step treatment based on cognitive-neuroscience insights. Anxiety and depression are emotional disorders that affect many Australian children and place them at risk of lifelong impairment. The latest evidence from cognitive science and neuroscience shows that these children have maladaptive thinking strategies that lead to avoidance and withdrawal. Capitalising on these basic science insights, this project exami ....Changing the lives of young Australians with emotional disorders using a simple three-step treatment based on cognitive-neuroscience insights. Anxiety and depression are emotional disorders that affect many Australian children and place them at risk of lifelong impairment. The latest evidence from cognitive science and neuroscience shows that these children have maladaptive thinking strategies that lead to avoidance and withdrawal. Capitalising on these basic science insights, this project examines a new treatment, referred to as the 'Emotional Flexibility Program', that targets childhood distress in three simple steps over just four weeks of treatment. This treatment could change the way childhood emotional disorders are treated and prevented, improve the quality of life for thousands of young Australians, and offset the associated economic burden of disease.Read moreRead less
Promoting the positive mental health and well being of young Australians. This project will test an innovative multidimensional model of positive mental health and mental illness in young Australians. It will also determine if the application of this model to the development of six online positive mental health tools, improves the mental health and well-being of young people.
Novel pharmacological agents to target stroke-induced brain injury. There is a looming stroke epidemic in Australia. 72% of Australian stroke sufferers are over the age of 65 and whereas in 1997 only 12% of Australians were in that age group, by 2030 that number will have increased to 23%. There is an urgent need for novel therapies. This project will aid the development of a novel anti-stroke therapy.
Improving workplace productivity via an AI-based physical activity chatbot . This project aims to develop, train and evaluate a physical activity chatbot using artificial intelligence and machine learning to improve workplace productivity in sedentary office workers. Productivity losses, due to high numbers of physically inactive workers, cost the Australian economy $14 billion per year. The cost of effective and scalable workplace physical activity programs acts as a barrier to their implementa ....Improving workplace productivity via an AI-based physical activity chatbot . This project aims to develop, train and evaluate a physical activity chatbot using artificial intelligence and machine learning to improve workplace productivity in sedentary office workers. Productivity losses, due to high numbers of physically inactive workers, cost the Australian economy $14 billion per year. The cost of effective and scalable workplace physical activity programs acts as a barrier to their implementation. As such, innovative programs that can reach large numbers of workers at minimal cost are needed. This project aims to generate new knowledge on the use of artificial intelligence to achieve behavioural improvements and will lead to the development of a new type of behaviour change program with broad applicability.
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Optimising how the brain processes language in healthy and neurological populations. This research will examine how the ability of the brain to process language can be modified by behavioural experiences, certain drugs and direct brain stimulation. The findings have the potential to reveal new ways to treat language disorders after brain injury or disease.
Transforming information systems design and use in social welfare agencies. This project aims to examine how electronic information systems (IS) can be redesigned to improve social welfare service delivery and support direct social work practice with those most in need. Using a proven ethnographic research design, this project aims to generate new knowledge and theory in the field of social informatics that is relevant to agencies across the sector. Expected outcomes of this project are practiti ....Transforming information systems design and use in social welfare agencies. This project aims to examine how electronic information systems (IS) can be redesigned to improve social welfare service delivery and support direct social work practice with those most in need. Using a proven ethnographic research design, this project aims to generate new knowledge and theory in the field of social informatics that is relevant to agencies across the sector. Expected outcomes of this project are practitioner-led and theoretically informed designs of IS and innovative ways to use them. Transforming the design and use of IS will enhance information about service activity and the needs of service users, thereby providing important benefits to the most vulnerable members of society.Read moreRead less
Testing theoretical propositions concerning the onset and progression of child-sex offending, and field testing a new sexual abuse prevention model. Child sexual abuse poses serious threats to the health and well-being of Australian children. Data from a variety of sources indicate that, for a variety of reasons, Indigenous children are exposed to a heightened risk of sexual abuse. The present project is expected to lead to new discoveries about the causes of sexual abuse and to new evidence-bas ....Testing theoretical propositions concerning the onset and progression of child-sex offending, and field testing a new sexual abuse prevention model. Child sexual abuse poses serious threats to the health and well-being of Australian children. Data from a variety of sources indicate that, for a variety of reasons, Indigenous children are exposed to a heightened risk of sexual abuse. The present project is expected to lead to new discoveries about the causes of sexual abuse and to new evidence-based prevention methods both within Indigenous communities and in the wider community. The project will therefore contribute at a national level, as well as at a local community level, to broader efforts to improve the life chances of Australian children.Read moreRead less
Psychosocial intervention to improve psychological and quality of life outcomes after cancer. Chronic diseases such as cancer have long-term negative effects on the quality of life of not only patients but also their carers. This project will develop effective ways to support individuals and carers to achieve optimal psychological and quality of life outcomes in the face of serious illness.