Genome-wide Association Study (GWAS) For Juvenile-onset Myopia And Its Component Measures To Identify Molecular Pathways To Prevent Myopia
Funder
National Health and Medical Research Council
Funding Amount
$495,364.00
Summary
We will examine 2,000 young adults from the Western Australian Raine Cohort at the Lions Eye Institute / University of Western Australia. Ocular data will be collected relating to myopia (short-sightedness) and will be combined with extensive previous childhood and genetic research data collected on the Cohort, to investigate the genetic and environmental factors predisposing to myopia. This will assist in understanding the factors leading to myopia.
Child Dental Benefit Policies and the Health of Australian Children. This project aims to examine the early effects of two recent initiatives by the Australian government to improve children’s dental health by providing funds to cover essential dental services for children from disadvantaged families. It explores the factors affecting eligible children’s access to benefits from these initiatives and identifies the causal impacts of these changed health care financing arrangements on children’s c ....Child Dental Benefit Policies and the Health of Australian Children. This project aims to examine the early effects of two recent initiatives by the Australian government to improve children’s dental health by providing funds to cover essential dental services for children from disadvantaged families. It explores the factors affecting eligible children’s access to benefits from these initiatives and identifies the causal impacts of these changed health care financing arrangements on children’s consumption of dental services, indicators of oral health and general health, and other indicators of cognitive and non-cognitive development. Using advanced econometric techniques and panel datasets, this project is expected to contribute to the development of effective policies for promoting health and wellbeing.Read moreRead less
The impact of adding nursing support workers (assistants in nursing) to patient, nurse and system (ward) level outcomes. This project will identify the impact of adding nursing support workers on outcomes for patients (morbidity, mortality, quality of emotional care); staff (job satisfaction, intention to remain in the job); and the work environment (time spent in patient care, relationships with medical staff, staff experiences, leadership and support of workers).
Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Group A Streptococcal Human Challenge Study: Accelerating Vaccine Development
Funder
National Health and Medical Research Council
Funding Amount
$2,018,741.00
Summary
Infection with group A streptococcus (GAS) is a major cause of morbidity and mortality worldwide, including in the Aboriginal population of Australia. Concerted efforts for vaccine development have been hampered by the absence of a suitable animal model. To address this critical knowledge gap we propose to develop a controlled human infection model of GAS infection. This model will provide a direct pathway for the future appraisal of novel GAS vaccines.
A Randomised Controlled Trial Of Interventional Versus Conservative Treatment Of Primary Spontaneous Pneumothorax
Funder
National Health and Medical Research Council
Funding Amount
$412,315.00
Summary
Primary spontaneous pneumothorax (PSP) is a collapsed lung that occurs in otherwise healthy people without underlying lung disease. Current standard treatment is to insert a chest drain into the chest to remove the air around the collapsed lung so that the lung re-inflates rapidly ("interventional treatment"). We will determine whether doing nothing, i.e. letting the lung re-inflate slowly on its own over several weeks ("conservative treatment"), is just as good or even better for patients.
Excessive sitting and population health: strengthening the science and the relevance to policy and practice. The majority of Australian adults spend most of their waking hours sitting; this increases the likelihood of developing diseases of inactivity, including diabetes, heart disease and some cancers. New research will investigate what factors encourage excessive sitting and what the health benefits are for people who deliberately do less sitting.
A prospective study investigating factors related to foster placement stability and the developmental outcomes of foster children. The study will aim to identify factors that influence the stability of placements and the developmental outcomes of children in foster care. The results of the study will have implications for the recruitment, training and support of foster carers. The study will lead to the refinement of procedures for the recruitment of appropriate foster carers, and the developmen ....A prospective study investigating factors related to foster placement stability and the developmental outcomes of foster children. The study will aim to identify factors that influence the stability of placements and the developmental outcomes of children in foster care. The results of the study will have implications for the recruitment, training and support of foster carers. The study will lead to the refinement of procedures for the recruitment of appropriate foster carers, and the development of an intervention for foster families relevant to the Australian context. Improving the developmental outcomes of children in foster care will help to reduce the intergenerational transmission of abuse and neglect and thus promote the mental health of the nation.Read moreRead less
A prospective evaluation of the impact of the nurse practitioner role on emergency department service and outcomes. The local hospital emergency department (ED) is a prominent and highly utilised service in Australian communities but demand on EDs is increasing, resulting in significant service delays. This project will study the composition of ED clinical teams around Australia and their impact on improving the timeliness and quality of emergency clinical care.
Evaluative learning: do all roads lead to Rome? This project aims to enhance understanding of how likes and dislikes are acquired and changed across a range of different settings. Evaluative learning, the acquisition and change of likes and dislikes, is ubiquitous and occurs in situations that range from trivial to traumatic. However, it is unknown whether evaluative learning in these different situations is mediated by a single or distinct learning mechanisms. Answering this question is critica ....Evaluative learning: do all roads lead to Rome? This project aims to enhance understanding of how likes and dislikes are acquired and changed across a range of different settings. Evaluative learning, the acquisition and change of likes and dislikes, is ubiquitous and occurs in situations that range from trivial to traumatic. However, it is unknown whether evaluative learning in these different situations is mediated by a single or distinct learning mechanisms. Answering this question is critically important for emotion science and the design of effective interventions for anxiety disorders and public health campaigns. The expected outcomes from this project will provide significant benefits, such as creating new knowledge to assist in applied areas ranging from the design of public health messages to the treatment for anxiety.Read moreRead less