Clinical Utility Of New Non-invasive Assessments Of Left Ventricular Function.
Funder
National Health and Medical Research Council
Funding Amount
$48,361.00
Summary
This project involves a series of studies that investigate the use of new ultrasound measurements of heart function in order to assess whether or nor they make a meaningful contribution to patient management, both in terms of diagnosis and monitoring of treatments. Major studies include: 1) Detection and prevention of early heart disease in patients who are undergoing toxic chemotherapy for cancer; and 2) Investigation and treatment of patients with a high blood pressure response to exercise.
Knee Osteoarthritis After Anterior Cruciate Ligament Reconstruction: The Relationship Between Function And Neuromechanics
Funder
National Health and Medical Research Council
Funding Amount
$76,252.00
Summary
Anterior cruciate ligament (ACL) reconstruction allows most people to return to their previous level of function, but does not prevent the onset of knee osteoarthritis (OA). The development of OA in young people after ACL reconstruction may be caused by the initial injury, altered movement patterns, or changes in muscle control. This study will investigate the relationship between these factors. The findings will help to improve understanding of the causes of OA following ACL reconstruction.
Platelet And Endothelial Function In Atrial Fibrillation
Funder
National Health and Medical Research Council
Funding Amount
$105,825.00
Summary
Atrial fibrillation is the most common heart rhythm disturbance in the adult population and leads to substantial increased death and disability from stroke. In this research scheme, we will study the contribution of platelet (clot forming cells) and endothelial (lining of blood vessels) dysfunction in atrial fibrillation. The successful outcome of this project will lead to a better understanding of the underlying mechanisms of clot formation and may lead to a better target for future drugs.
Assessment Of Left Atrial Function Using Electro-anatomic Mapping And Cardiac Magnetic Resonance Imaging
Funder
National Health and Medical Research Council
Funding Amount
$82,554.00
Summary
This study aims to use a novel imaging technique, cardiac magnetic resonance imaging, to assess the structure, function and blood flow of the heart chambers in patients with a heart rhythm abnormality called atrial fibrillation. Atrial fibrillation is the most common heart rhythm abnormality and is a significant cause of stroke in Australia. This study may provide us with better tools to assess the risk of stroke in patients with atrial fibrillation and allow targeted preventive strategies.