Opening a New Era of High-Performance Microwave Devices. We propose a conceptually new method of manufacturing high-performance microwave components at the low-cost and short lead time using liquid form conductors and 3D printing technology. Innovation consists in developing surface roughness free waveguide- and coaxial-based RF and microwave devices, in one-single-piece. This technique can be further extended to create high-performance reconfigurable RF and microwave devices such as filters, an ....Opening a New Era of High-Performance Microwave Devices. We propose a conceptually new method of manufacturing high-performance microwave components at the low-cost and short lead time using liquid form conductors and 3D printing technology. Innovation consists in developing surface roughness free waveguide- and coaxial-based RF and microwave devices, in one-single-piece. This technique can be further extended to create high-performance reconfigurable RF and microwave devices such as filters, antennas, directional couplers, phase shifters and switches by manipulating the locations of the liquid conductors. Furthermore, the method will enable the management of heat generated in high-power applications. Australian telecommunication industry and defence will benefit from the outcome of this project.Read moreRead less
Androgen receptor: A master regulator of lipid metabolism. This project aims to understand how male sex hormones, or androgens, affect the amount and metabolism of fats in normal body tissues. By integrating our multi-disciplinary expertise in androgen action, molecular biology, metabolism and bioinformatics with novel techniques and instrumentation, this collaboration expects to generate the first detailed picture of how fat metabolism is controlled by androgens in humans, and how closely this ....Androgen receptor: A master regulator of lipid metabolism. This project aims to understand how male sex hormones, or androgens, affect the amount and metabolism of fats in normal body tissues. By integrating our multi-disciplinary expertise in androgen action, molecular biology, metabolism and bioinformatics with novel techniques and instrumentation, this collaboration expects to generate the first detailed picture of how fat metabolism is controlled by androgens in humans, and how closely this relates to mice. Expected outcomes and benefits will be a new understanding of which aspects of fat metabolism are most influenced by androgens, and an ability to anticipate potential metabolic impacts of natural or pharmacological fluctuations in androgen levels in humans, laboratory animals and livestock.Read moreRead less
A network perspective for ecosystem responses to plant invasion. Invasive species are key drivers of global change, yet, our understanding of their negative impacts on ecosystems is limited within many contexts. This project will provide the first large-scale test for interactions between plants and microbes, via network analyses, as yardsticks for invasive species impacts on ecosystems. Using innovative approaches that link interactions network properties with ecosystem functioning, the fundame ....A network perspective for ecosystem responses to plant invasion. Invasive species are key drivers of global change, yet, our understanding of their negative impacts on ecosystems is limited within many contexts. This project will provide the first large-scale test for interactions between plants and microbes, via network analyses, as yardsticks for invasive species impacts on ecosystems. Using innovative approaches that link interactions network properties with ecosystem functioning, the fundamental data generated in this study will answer unsolved theoretical questions, providing evidence for the use of networks to predict and mitigate invader impacts. These benefits are not only crucial for biodiversity managers but also for those responsible for sustainable crop development under future climates.Read moreRead less
Internet Timing for the Ages: Establishing the New Timekeeping System. All computers incorporate a software clock, essential to myriad software applications. An economic way to synchronize such clocks is over a network, however the approach the Internet currently depends upon is unreliable and vulnerable. This project aims to establish a new architecture for networked timekeeping, built on future-proofed fundamentals, that will for the first time address each of accuracy, reliability, and trust. ....Internet Timing for the Ages: Establishing the New Timekeeping System. All computers incorporate a software clock, essential to myriad software applications. An economic way to synchronize such clocks is over a network, however the approach the Internet currently depends upon is unreliable and vulnerable. This project aims to establish a new architecture for networked timekeeping, built on future-proofed fundamentals, that will for the first time address each of accuracy, reliability, and trust. The expected outcome is a national prototype, serving the public with accurate and trusted time, that will form the basis of the next generation timekeeping system for the Internet and the Internet of Things. Expected benefits include enhanced productivity across the digital economy, and resilience to GPS failures.Read moreRead less
Terabit mm-Wave Backbones for Integrated Space and Terrestrial Networks. This project aims to develop the theory and enabling techniques to achieve high-speed millimeter wave (mm-wave) backbones for integrated space and terrestrial networks. New scientific breakthroughs will be in fundamental transmission theory, efficient self-interference cancellation and spatial multiplexing techniques using hybrid antenna arrays. These will enable Terabits per second wireless transmission that is 10 times fa ....Terabit mm-Wave Backbones for Integrated Space and Terrestrial Networks. This project aims to develop the theory and enabling techniques to achieve high-speed millimeter wave (mm-wave) backbones for integrated space and terrestrial networks. New scientific breakthroughs will be in fundamental transmission theory, efficient self-interference cancellation and spatial multiplexing techniques using hybrid antenna arrays. These will enable Terabits per second wireless transmission that is 10 times faster than current technologies. A proof-of-concept prototype will be developed to demonstrate the feasibility and performance of the new system architecture and algorithms, thus paving the way for commercialisation. The developed technology will enhance Australia’s information infrastructure as well as defence capacity.Read moreRead less
Assembling the building blocks in the blueprint of the embryonic head. This project aims to profile and impute the genome activity and validate the cellular and molecular mechanism underpinning the generation, in time and space, of diverse types of tissues that constitute the building blocks of the embryonic head. The knowledge gain enriches our understanding of the early steps of head formation during embryogenesis in the context of the niche conditions associated with the acquisition of progen ....Assembling the building blocks in the blueprint of the embryonic head. This project aims to profile and impute the genome activity and validate the cellular and molecular mechanism underpinning the generation, in time and space, of diverse types of tissues that constitute the building blocks of the embryonic head. The knowledge gain enriches our understanding of the early steps of head formation during embryogenesis in the context of the niche conditions associated with the acquisition of progenitor state, enhancement of lineage propensity, and driving early lineage differentiation. Expected outcome of this research on the developmental biology of a model organism provides a framework of the mechanism of establishing a blueprint of development that may be conserved across multiple mammalian species.Read moreRead less