Enhancing Host Defence Mechanisms In Severe Bacterial Infections
Funder
National Health and Medical Research Council
Funding Amount
$830,447.00
Summary
New options to treat bacterial infections are needed because of the rapid increase in antibiotic resistance. One very attractive strategy is to boost the body’s own defence mechanisms against bacteria. This project defines novel molecular mechanisms that can be manipulated to better control a bacterial infection. Novel drugs targeting these molecular pathways are already being developed, albeit for cancer. This project will help assess if these drugs may be useful to treat infections.
Dissecting Immune Responses To Salmonella Infection
Funder
National Health and Medical Research Council
Funding Amount
$415,797.00
Summary
Successful treatment of Salmonella infections requires a detailed understanding how Salmonella growth is controlled. This project will examine the role of white blood cells, will reveal how they contribute to the control of Salmonella infections and will test novel treatment options. The outcome of this project will significantly advance our understanding of immune responses against Salmonella.