Detecting stress-induced changes to subcellular copper pools in brain cells. Copper (Cu) plays essential roles in the functioning of brain cells, but the regulation and activity of this metal is poorly understood. This project aims to map sub-cellular Cu pools in brain cells, with particular emphasis on the effects of cellular stresses on these pools. These studies are expected to contribute important new methods for the study of Cu biology, and could provide valuable information about how Cu ho ....Detecting stress-induced changes to subcellular copper pools in brain cells. Copper (Cu) plays essential roles in the functioning of brain cells, but the regulation and activity of this metal is poorly understood. This project aims to map sub-cellular Cu pools in brain cells, with particular emphasis on the effects of cellular stresses on these pools. These studies are expected to contribute important new methods for the study of Cu biology, and could provide valuable information about how Cu homeostasis is maintained or perturbed under various stresses. In the future, this work is expected to form the basis of studies of brain Cu pools in neurodegenerative diseases.Read moreRead less
Quantifying the impact of phenotypic plasticity on population persistence. This project aims to understand how environmental sensitivity in growth, survival and reproduction of individuals in a population influence population dynamics using terrestrial ectotherms. It will provide significant new insights into whether phenotypic plasticity promotes population persistence in the face of environmental change. Expected outcomes include approaches for incorporating environmental effects in population ....Quantifying the impact of phenotypic plasticity on population persistence. This project aims to understand how environmental sensitivity in growth, survival and reproduction of individuals in a population influence population dynamics using terrestrial ectotherms. It will provide significant new insights into whether phenotypic plasticity promotes population persistence in the face of environmental change. Expected outcomes include approaches for incorporating environmental effects in population models for threatened species, open databases that can be used to estimate demographic information for species lacking data, and an assessment of what characteristics make some species more sensitive to the environment than others. Benefits include quantitative training and tools for managing Australia's rich biodiversity.Read moreRead less
The mighty ape’s last stand. This project aims to study the fate of primates in southern Asia, where evidence for megafaunal extinction is rare. Why Gigantopithecus blacki, the largest ever primate, disappeared is unknown, while humans in the region survived. This project will model dating techniques across sites to identify a precise extinction window and compare behaviour and past environmental conditions to determine why the ape failed and man persevered. Outcomes will generate a new understa ....The mighty ape’s last stand. This project aims to study the fate of primates in southern Asia, where evidence for megafaunal extinction is rare. Why Gigantopithecus blacki, the largest ever primate, disappeared is unknown, while humans in the region survived. This project will model dating techniques across sites to identify a precise extinction window and compare behaviour and past environmental conditions to determine why the ape failed and man persevered. Outcomes will generate a new understanding of past environmental change as a driver of megafaunal extinction in comparison with human adaption and survival.Read moreRead less
Future Keepers: impacts of climate change on ecosystem function providers. The aim of this project is to predict how key ecosystem service providers may change under resource limitation and thermal stress. The project seeks to assess how common species respond to climatic fluctuations and resource limitations when competing for resources in familiar and novel environments along six biogeographic transects throughout Australia. In combination with hypothesis-driven field, laboratory and transplan ....Future Keepers: impacts of climate change on ecosystem function providers. The aim of this project is to predict how key ecosystem service providers may change under resource limitation and thermal stress. The project seeks to assess how common species respond to climatic fluctuations and resource limitations when competing for resources in familiar and novel environments along six biogeographic transects throughout Australia. In combination with hypothesis-driven field, laboratory and transplant experiments, citizen science will be used to create a longitudinal data set of the constraints put on dominant and functionally important species. The project also seeks to enable more robust forecasting of biological responses to environmental change by integrating both empirical and theoretical capabilities.Read moreRead less
ARC Centre of Excellence for the Elimination of Violence Against Women. ARC Centre of Excellence for the Elimination of Violence Against Women. Eliminating violence against women is one of the major challenges of the 21st century. Awareness of the problem has grown exponentially, but solutions to it have not. This Centre aims to transform our understanding of the problem by examining the structural drivers that cause and compound violence against women, and pioneering new, evidence-based approac ....ARC Centre of Excellence for the Elimination of Violence Against Women. ARC Centre of Excellence for the Elimination of Violence Against Women. Eliminating violence against women is one of the major challenges of the 21st century. Awareness of the problem has grown exponentially, but solutions to it have not. This Centre aims to transform our understanding of the problem by examining the structural drivers that cause and compound violence against women, and pioneering new, evidence-based approaches to radically improve policy and practice across Australia and the Indo-Pacific. The Centre mobilises survivor-centric and Indigenous methodologies, interdisciplinary collaborations, and Indo-Pacific partnerships to deliver scalable approaches to eliminate violence against women across the legal, security, economic, health, and political systems of Australia and the region.Read moreRead less
How does your garden grow? Scaling functional traits to whole-plant growth. Understanding how the traits of leaves and stems influence plant growth is important because plant growth drives emergent ecosystem properties such as rates of water use and carbon and nitrogen cycling. The project will build a new understanding of trait-growth relationships, focusing on species from four Australian forest types.
Special Research Initiatives - Grant ID: SR0354797
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance co ....The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance communication, bring together innovative skill sets, create linkages, generate focussed research programs and foster novel commercial opportunities. Ultimately the Initiative and Network will deliver an improved quality of life, reduced healthcare costs, and increased productivity to Australia.Read moreRead less
Determining fossilisation processes of a rare iron-rich Lagerstätte. Most fossil sites only preserve resistant elements such as bones and teeth, leading to questions about how soft animals and structures have evolved over time. The recent discovery of a fossil deposit in New South Wales appears to demonstrate a new set of conditions for the preservation of soft tissues. This project aims to constrain the age of and assess the fossilisation processes that produced this unique fossil site. We will ....Determining fossilisation processes of a rare iron-rich Lagerstätte. Most fossil sites only preserve resistant elements such as bones and teeth, leading to questions about how soft animals and structures have evolved over time. The recent discovery of a fossil deposit in New South Wales appears to demonstrate a new set of conditions for the preservation of soft tissues. This project aims to constrain the age of and assess the fossilisation processes that produced this unique fossil site. We will use an integrative approach to reconstruct the formation of this Lagerstätte. The work will provide significant advances in our understanding of the process of fossilisation and guide the discovery of other exceptionally-well preserved fossil deposits, critical in reconstructing the biological history of Australia.Read moreRead less
Diatom silica production under future ocean conditions, genes to biomes. This project aims to quantify how ocean warming and acidification will alter natural diatom assemblages and silica production rates to predict changes in the cycling and transfer of carbon and silicon in the future ocean. This project expects to generate new knowledge of environmental controls on diatom silicification and their ocean-scale implications by integrating the disciplines of physiology, molecular biology and quan ....Diatom silica production under future ocean conditions, genes to biomes. This project aims to quantify how ocean warming and acidification will alter natural diatom assemblages and silica production rates to predict changes in the cycling and transfer of carbon and silicon in the future ocean. This project expects to generate new knowledge of environmental controls on diatom silicification and their ocean-scale implications by integrating the disciplines of physiology, molecular biology and quantitative modelling. Expected outcomes include essential advancements in future simulations of marine productivity and silicon cycling and a deeper understanding of threats to marine life from climate change. This should provide significant benefits such as improved valuations on the sustainability of ocean ecosystems.Read moreRead less