Microfluidic Strategy For Circulating Tumour Cells Analysis In Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$429,180.00
Summary
My approach and ultimate goal over the next 4 years is to demonstrate the use of recently discovered “Nanoshearing” technology as a standard diagnostic tool for cancer patients undergoing systemic therapy and assess the impact of standard protocols in predicting response to therapy and patient outcomes. Data from this study could potentially define new standards of clinical practice, as they relate to follow-up screening for response to therapy and recurrence of disease.
Improving Sexual Health In Men With Prostate Cancer: Randomised Controlled Trial Of Exercise And Psychosexual Therapies
Funder
National Health and Medical Research Council
Funding Amount
$583,416.00
Summary
Sexual dysfunction is one of the most common and distressing side effects of prostate cancer. Despite being a critical survivorship care issue, there is a clear gap in knowledge surrounding the optimal treatment of sexual dysfunction in men with prostate cancer. This project examines whether exercise aids in the management of sexual dysfunction and explores if an integrated treatment model incorporating pharmacological, exercise and psychosexual therapies maximises improvement in sexual health.
Individualising Care For Patients With Chronic Hepatitis C: Predicting Side Effects And Treatment Response Using Genomic And Proteomic Approaches.
Funder
National Health and Medical Research Council
Funding Amount
$55,575.00
Summary
Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially impro ....Patients undergoing treatment for hepatitis C must endure a treatment characterized by unpredictable treatment side effects and uncertainty about the likelihood of cure. This project will investigate genetic predictors of treatment related side-effects and protein markers to predict treatment response. Better definition of the risks and benefits of therapy, may facilitate patients and clinicians to make more informed decisions about treatment, thus individualising treatment and potentially improving the safety and efficacy of therapy.Read moreRead less
Which Modifiable Risk Factors Actually Cause Cancer?
Funder
National Health and Medical Research Council
Funding Amount
$384,076.00
Summary
Observational studies suggest that modifiable risk factors such as low vitamin D levels, coffee consumption, alcohol consumption and obesity may be important in cancer risk. However, observational studies can only demonstrate association between a risk factor and cancer, and association does not equal causation. We present an alternative approach to help determine which risk factors actually cause cancer.
International franchising success factors: A guide for Australian franchise systems. Australia is considered the most 'franchised' nation in the world. With 850 franchisors, it has over three times the number of systems per capita than the United States. However, Australian franchises are small due to the country's limited population, with 60% of systems holding fewer than 30 units. One third of Australian franchisors now operates internationally, however little is known about how they plan an ....International franchising success factors: A guide for Australian franchise systems. Australia is considered the most 'franchised' nation in the world. With 850 franchisors, it has over three times the number of systems per capita than the United States. However, Australian franchises are small due to the country's limited population, with 60% of systems holding fewer than 30 units. One third of Australian franchisors now operates internationally, however little is known about how they plan and implement their expansion strategies. It appears that franchisors are reacting to approaches made by overseas investors rather than proactively developing international expansion strategies. This research will examine the practices of successful exporters to develop a model of best practice for future activity in the sector.Read moreRead less
An integrated mathematical approach to synchronise and optimise hospital operations. This project aims to develop an integrated mathematical approach to synchronise and optimise patient scheduling systems of different departments to ensure that the hospital’s assets and related resources are used efficiently. The project’s aim is to investigate patient flow, process delay, and the interaction and inter-dependence of departments within the hospital to reduce access block (bottleneck) and subseque ....An integrated mathematical approach to synchronise and optimise hospital operations. This project aims to develop an integrated mathematical approach to synchronise and optimise patient scheduling systems of different departments to ensure that the hospital’s assets and related resources are used efficiently. The project’s aim is to investigate patient flow, process delay, and the interaction and inter-dependence of departments within the hospital to reduce access block (bottleneck) and subsequent overcrowding. This project aims to smooth the running of the hospital, improve the efficiency of patient throughput, reduce waiting times, and revolutionise hospital planning and scheduling.Read moreRead less
Australian Partnership (for) Preparedness Research On InfectiouS (disease) Emergencies (APPRISE)
Funder
National Health and Medical Research Council
Funding Amount
$4,996,416.00
Summary
We have assembled national experts in clinical, laboratory and public health research to ensure Australia is equipped for a coordinated, effective and evidence based response to infectious diseases. This multidisciplinary team will create and share new knowledge to detect, prevent and manage emerging infection threats. We will train a robust cross-sectoral work force and develop sustainable research capacity integrated within the health system to ensure national and regional health security.
Optimisation of Rail Network Infrastructure Capacity under Dynamic Train Planning. Recent changes in railway operating environments have caused significant operational and management problems in Australia. This research will lead to improvements of railway's key managerial functions, namely: network capacity planning; rollingstock planning; train scheduling; and maintenance planning. The major outcome of the research will be to develop an optimisation model to significantly improve the operati ....Optimisation of Rail Network Infrastructure Capacity under Dynamic Train Planning. Recent changes in railway operating environments have caused significant operational and management problems in Australia. This research will lead to improvements of railway's key managerial functions, namely: network capacity planning; rollingstock planning; train scheduling; and maintenance planning. The major outcome of the research will be to develop an optimisation model to significantly improve the operating efficiency and assets productivity of Australia's rail system. The novelty of the research is that it will be undertaken using innovations based on modern job shop scheduling and sequencing optimisation techniques as the complexity of the problem makes it impossible to solve by classic optimisation techniques.Read moreRead less
From The Laboratory To The Classroom: Validation Of An Innovative Laboratory Model Of Adolescent Impulsivity And Alcohol Use Using A School-based Randomised Controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$399,267.00
Summary
I am a psychologist focused on understanding how different psychosocial approaches to reducing adolescent alcohol use actually work. I will achieve this using a new laboratory model I have developed to determine the “active ingredients” of different interventions. Using a randomised controlled trial, I will then test whether combining these ingredients produces better outcomes in the prevention of teenage drinking.