Inflammatory Pathways For Novel Therapeutic Interventions In Preterm Delivery
Funder
National Health and Medical Research Council
Funding Amount
$568,006.00
Summary
Preterm birth is common and carries severe risks for the child. Existing therapies are not very successful in arresting preterm labour or improving outcomes for the fetus. We have discovered that blocking inflammatory ‘sensor’ molecules can slow labour progression. This project will (1) increase our knowledge of the inflammatory pathways that initiate early labour, and (2) define the mechanism of action and safety of a new drug that has potential for delaying preterm birth in women.
Transport risk pathways for emerging invasive species. Our Australian economy depends on tourism and trade and this carries unavoidable risks for the introduction and establishment of new invasive pests and diseases. This project will build datasets from four real-world problem agenda in global invasion biology. Informed by these data, this project will develop and apply state-of-the-art mathematical transport models to predict the risks and frequency of future biological invasion events. The pr ....Transport risk pathways for emerging invasive species. Our Australian economy depends on tourism and trade and this carries unavoidable risks for the introduction and establishment of new invasive pests and diseases. This project will build datasets from four real-world problem agenda in global invasion biology. Informed by these data, this project will develop and apply state-of-the-art mathematical transport models to predict the risks and frequency of future biological invasion events. The project will contribute directly to safeguarding Australia from invasive pests and diseases.Read moreRead less
Systematic Expansion Of The Clinical Evidence Base In Opioid Prescribing For Refractory Dyspnoea At The End Of Life
Funder
National Health and Medical Research Council
Funding Amount
$414,535.00
Summary
Morphine can relieve breathlessness in the palliative setting. But many important questions remain. What is the best dose, should the dose change over time, do different medications provide the same relief, and how common is dyspnoea in the general population? This three part project will extend our knowledge to answer these questions. Population data will provide critical background to plan best care for future palliative patients distressed by breathlessness.