Disease in endangered species: The importance of multiple-host infection and spatial structure. Pathogens are increasingly recognised as threats to endangered species. Managing such threats requires models to assess alternative strategies. Most current models deal with a single host and single pathogen, without spatial structure, although multiple-host pathogens pose the greatest conservation threats. This project develops a new generation of spatially-structured multiple-host models, and applie ....Disease in endangered species: The importance of multiple-host infection and spatial structure. Pathogens are increasingly recognised as threats to endangered species. Managing such threats requires models to assess alternative strategies. Most current models deal with a single host and single pathogen, without spatial structure, although multiple-host pathogens pose the greatest conservation threats. This project develops a new generation of spatially-structured multiple-host models, and applies them to two case studies. The first is the chytrid fungus that is thought to have lead to widespread declines and extinctions of frogs in Australia and overseas. The second is birdpox and malaria that have led to the extinction and endangerment of much of Hawaii's endemic avifauna.Read moreRead less
Neural correlates of performance trade-offs and interference in dual-task performance. Our daily lives are characterised by our ability to produce and sustain a wide range of different movement patterns and to deliberately change patterns as the situation demands. In this project we seek to understand the relationship between brain processes, attentional demands, and the control and learning of coordinated behaviour. A further aim will be to examine how this relationship may be altered as a re ....Neural correlates of performance trade-offs and interference in dual-task performance. Our daily lives are characterised by our ability to produce and sustain a wide range of different movement patterns and to deliberately change patterns as the situation demands. In this project we seek to understand the relationship between brain processes, attentional demands, and the control and learning of coordinated behaviour. A further aim will be to examine how this relationship may be altered as a result of aging, degenerative disease, or brain damage. This research will provide a foundation upon which rehabilitation strategies can be developed for the movement impaired.Read moreRead less
Investigating the genetic basis for heterogeneous susceptibility of Tasmanian devils to a novel infectious cancer. This project will use genetics and modelling to reveal why Tasmanian devils in northwest Tasmania are not dying from facial tumour disease, a new, unusual infectious cancer threatening this iconic carnivore with extinction. This project will predict extinction risk, develop management options, and provide a new template for managing emerging wildlife diseases.
Facilitatory and inhibitory mechanisms during interlimb coordination in young and older adults. The project seeks to understand how people coordinate their limbs and the factors which limit and enhance this capacity. This is of critical importance because coordination is a dominant deficit in aging and in patients suffering brain insult and neurodegenerative diseases. Disruption of this capacity compromises individual work productivity, mobility and independence. Proficient motor functioning is ....Facilitatory and inhibitory mechanisms during interlimb coordination in young and older adults. The project seeks to understand how people coordinate their limbs and the factors which limit and enhance this capacity. This is of critical importance because coordination is a dominant deficit in aging and in patients suffering brain insult and neurodegenerative diseases. Disruption of this capacity compromises individual work productivity, mobility and independence. Proficient motor functioning is an important lifestyle factor as humans age and deficits in coordinated muscle activity will increase the risk of falls which are the leading cause of injury in elderly adults. Identification of changes in brain processes involved in interlimb coordination will allow for the development of strategies to improve motor functions in the aged.Read moreRead less
Interlimb coordination dynamics in stroke. Everyday we use our limbs in a coordinated manner. However, for a person who has suffered a stroke resulting in weakness on one side of the body even the simplest interlimb coordination tasks are difficult to perform. This project will examine interlimb coordination in persons who have suffered a stroke and explore whether the coupling between limbs can be exploited to promote fuctional recovery of an impaired limb. In particular, the research seeks to ....Interlimb coordination dynamics in stroke. Everyday we use our limbs in a coordinated manner. However, for a person who has suffered a stroke resulting in weakness on one side of the body even the simplest interlimb coordination tasks are difficult to perform. This project will examine interlimb coordination in persons who have suffered a stroke and explore whether the coupling between limbs can be exploited to promote fuctional recovery of an impaired limb. In particular, the research seeks to identify the critical components underlying the effectiveness of an intervention involving the pratice of actions bilaterally and simultaneously.Read moreRead less
Prediction of radiated noise from marine propellers. Underwater noise radiated from marine vessels is a significant problem for research, fishing and military vessels, and is a major source of pollution in the marine environment. The major source contributing to underwater noise is due to the propeller. This work will develop numerical models with experimental validation that can accurately predict the sources of noise generated by marine propellers and acoustic signatures of marine vessels due ....Prediction of radiated noise from marine propellers. Underwater noise radiated from marine vessels is a significant problem for research, fishing and military vessels, and is a major source of pollution in the marine environment. The major source contributing to underwater noise is due to the propeller. This work will develop numerical models with experimental validation that can accurately predict the sources of noise generated by marine propellers and acoustic signatures of marine vessels due to propeller motion. This work has great significance for Australia’s construction and military maritime industries. The technologies developed in this project are also applicable to rotors in other industries such as in aircraft, helicopters and wind turbines.Read moreRead less
An investigation of limb dynamics as a constraint on human motor learning. Everyday we use our limbs to interact with a variety of objects. These objects have various mechanical characteristics (dynamics), which require the human motor system to provide appropriate control. This project seeks to understand how the brain, in both normal and disease states, learns new limb dynamics as we interact with a novel mechanical environmental. Repetitive brain stimulation will be used to selectively block ....An investigation of limb dynamics as a constraint on human motor learning. Everyday we use our limbs to interact with a variety of objects. These objects have various mechanical characteristics (dynamics), which require the human motor system to provide appropriate control. This project seeks to understand how the brain, in both normal and disease states, learns new limb dynamics as we interact with a novel mechanical environmental. Repetitive brain stimulation will be used to selectively block the contribution of various cortical regions during the learning of a new motor skill and later, the recall of that skill. This will allow us to determine definitively which areas are critical to motor skill acquisition.Read moreRead less
Impact of Metal - Reactive Oxygen Species (ROS) Interactions on Growth and Toxicity of Ichthyotoxic Algae in Australian Coastal Waters. Toxic algal blooms in estuarine and coastal waters can have devastating economic and ecological impacts but remarkably little is known about the factors that control either organism growth or toxin severity. Recent studies suggest that the interplay between delivery of the nutrient trace metals iron and copper and the method via which the organism acts to assimi ....Impact of Metal - Reactive Oxygen Species (ROS) Interactions on Growth and Toxicity of Ichthyotoxic Algae in Australian Coastal Waters. Toxic algal blooms in estuarine and coastal waters can have devastating economic and ecological impacts but remarkably little is known about the factors that control either organism growth or toxin severity. Recent studies suggest that the interplay between delivery of the nutrient trace metals iron and copper and the method via which the organism acts to assimilate these metals is critical to the generation and aggressiveness of the toxins produced. These processes will be investigated in this study and conceptual and mathematical models will be developed which will assist in assessing management options for estuarine and coastal environments.Read moreRead less
Effects of invasive macrofauna on marine biodiversity and ecosystem function. The project will identify environmental and biological factors that help prevent invasion of native marine communities by introduced pests, and describe thresholds in marine systems where further loss of macrofaunal species results in declines in ecosystem health.
Conserving wildlife at landscape-scales. The project aims to conserve threatened wildlife at large scales in unfenced landscapes. Using empirical field experiments in Australia and New Zealand, the project will test how suppressing populations of invasive prey – rabbits – could reduce the effect of invasive predators – cats – on native wildlife. Feral cats threaten biodiversity globally, including Australia and New Zealand. Effective control of cats is difficult at large-scales but rabbit contro ....Conserving wildlife at landscape-scales. The project aims to conserve threatened wildlife at large scales in unfenced landscapes. Using empirical field experiments in Australia and New Zealand, the project will test how suppressing populations of invasive prey – rabbits – could reduce the effect of invasive predators – cats – on native wildlife. Feral cats threaten biodiversity globally, including Australia and New Zealand. Effective control of cats is difficult at large-scales but rabbit control is feasible. The project aims to provide a conceptual approach for biodiversity conservation that can be scaled up to mitigate the effects of invasive predators at large scales globally and allow restoration of ecosystems.Read moreRead less