Advanced Glycation End Products As Risk Factors For Type 1 Diabetes
Funder
National Health and Medical Research Council
Funding Amount
$80,040.00
Summary
There is no cure for type 1 diabetes which manifests in children and adolescents resulting in the need for 5 injections of insulin each day. During this scholarship period, we aim to discover new genetic and blood biomarkers for disease onset in children for use in new born and childhood screening. In addition we will determine if specific environmental factors called advanced glycation end products can contribute to type 1 diabetes via interactions with a specific gene, RAGE.
Early Childhood Education: Can Kindergarten Reduce The Risk Of Adult Metabolic Syndrome And Cardiovascular Disease?
Funder
National Health and Medical Research Council
Funding Amount
$100,381.00
Summary
This study aims to examine the pre-school early learning environment and its impact on adult cardiovascular health outcomes and consequently health system costs. If it is found that adult metabolic syndrome and cardiovascular health outcomes can improve with attendance at kindergarten, it may be possible to encourage kindergarten attendance for all children to systematically alter the developmental trajectory of children and as such improve the cardiovascular health of the entire population.
Identification Of Key Enzymes Required For Efficient Post-translational Modification And Multimerisation Of Adiponectin
Funder
National Health and Medical Research Council
Funding Amount
$92,364.00
Summary
Obesity is a major national and global health issue, with 62% of adult Australians being overweight/obese, associated with a number of diseases such as type 2 diabetes and cardiovascular disease. Fat tissue secretes hormones and dysregulation of these hormones contributes to the development of obesity-associated disease. This project aims to define processes governing the secretion of one key hormone and ultimately to identify targets for the treatment of obesity-associated complications.