Role of suppressor of cytokine signalling proteins (SOCS3) in defective muscle repair and ageing. Old muscles are slower and weaker than young muscles, they are injured more easily and they repair less successfully. This proposal investigates the role of SOCS3-signalling in muscle repair, ultimately to improve healing and to promote healthy ageing that will enable older Australians to enjoy a better quality of life.
Complexity-manageable methodologies and efficient computational tools for analysis and design of large-scale systems. The tools to be developed in this project have impact on a broad range of disciplines, including system analysis, feedback control technology, signal processing, communication network, and information theory. Practically, the success of this project will create cutting edge technologies applicable to design and management of important infrastructures of the modern society such as ....Complexity-manageable methodologies and efficient computational tools for analysis and design of large-scale systems. The tools to be developed in this project have impact on a broad range of disciplines, including system analysis, feedback control technology, signal processing, communication network, and information theory. Practically, the success of this project will create cutting edge technologies applicable to design and management of important infrastructures of the modern society such as communication networks, transportation systems, electrical power grids, and collaborative intelligent machines, and water distribution networks. Success of this project will bring novel methodologies and computational tools which help engineers to systematically design and validate the performance of their engineering systems.Read moreRead less
Robustness Analysis and Control Design of Distributed and Networked Systems. The theory and computational tools to be developed in this project have impact on a broad range of areas, including various engineering disciplines, biology, and medical and environmental sciences. In terms of practical interests, this project will create cutting edge technologies which are applicable to important infrastructures of the modern society such as communication networks, transportation systems, electrical po ....Robustness Analysis and Control Design of Distributed and Networked Systems. The theory and computational tools to be developed in this project have impact on a broad range of areas, including various engineering disciplines, biology, and medical and environmental sciences. In terms of practical interests, this project will create cutting edge technologies which are applicable to important infrastructures of the modern society such as communication networks, transportation systems, electrical power grids, collaborative intelligent machines, and water distribution networks. Read moreRead less
Role of Musashi in the regulation of cell cycle proteins. We have identified a protein family that directs cell fate and maintains male fertility. This project will provide new avenues for generation of contraceptives in male animals and to regulate stem cells for production of specialised cell types in biotechnological applications.
Variable Structure Control Systems in Networked Environments. This project will be the first in the world to lay the foundation for a new theory for understanding and designing new variable structure control systems in the networked environments, which is in great need due to increasing use of shared communication networks in modern industrial systems. It will firmly place Australia at the forefront of this research by developing a cutting edge technology for improving reliability and efficiency ....Variable Structure Control Systems in Networked Environments. This project will be the first in the world to lay the foundation for a new theory for understanding and designing new variable structure control systems in the networked environments, which is in great need due to increasing use of shared communication networks in modern industrial systems. It will firmly place Australia at the forefront of this research by developing a cutting edge technology for improving reliability and efficiency of industrial variable structure control systems in the networked environments, hence resulting in cost-saving and improved productivity for industry. It will provide training for new leading researchers specialised in this new theory and technology.Read moreRead less
What learning is there in learning control? This project seeks to establish a meaningful definition and quantifiable measure of learning in the context of adaptive or learning control. The project is designed within the context of human motor skill learning, and assesses the speed of learning and the quality of learning (reflected by the accuracy of the motor task execution). The project plans to use measures to provide a mathematically precise meaning for the notion of learning. The outcome has ....What learning is there in learning control? This project seeks to establish a meaningful definition and quantifiable measure of learning in the context of adaptive or learning control. The project is designed within the context of human motor skill learning, and assesses the speed of learning and the quality of learning (reflected by the accuracy of the motor task execution). The project plans to use measures to provide a mathematically precise meaning for the notion of learning. The outcome has the potential to be applied to the design of technology-assisted training of motor skills, from the recovery of lost motor skills after trauma to the development of elite athletes.Read moreRead less
In vivo assembly and virulence of poxvirus infectious crystals. Widespread insect viruses have evolved unique infectious forms called crystalline armours. This project will use innovative biophysical approaches to understand how these virus-containing crystals assemble and package viruses and contribute to virulence as a rational basis for improved bioinsecticides and novel microparticles for biotechnological applications.
Renewable energy generation from flow-induced vibration. Much engineering effort has been expended to eliminate vibration of marine structures. This project seeks to provide the basis for the development of tidal energy harnessing, by deliberately amplifying and harnessing vibration. This technology offers the promise of capturing clean, zero-emissions energy, while presenting no risk to marine life.
Studying Discretisation Behaviours in Variable Structure Control Systems. Variable structure control is a technology that helps build very simple and effective switching control devices for dealing with environmental uncertainties, which are widely used, for example, in industrial control systems/processes. The outcomes from this research will help the understanding of control performance deterioration due to discretisation and developing effective measures for protection from possible ill beha ....Studying Discretisation Behaviours in Variable Structure Control Systems. Variable structure control is a technology that helps build very simple and effective switching control devices for dealing with environmental uncertainties, which are widely used, for example, in industrial control systems/processes. The outcomes from this research will help the understanding of control performance deterioration due to discretisation and developing effective measures for protection from possible ill behaviours of these control devices. This research will place Australia in the forefront of the development of this new technology, resulting in enhanced reliability of control devices, improved productivity and cost saving for industries, and consequent improvement in quality of life.Read moreRead less
The social determinants of childhood injury. Child hood injury is a preventable problem of major importance. This project will provide a comprehensive, research-based policy solution that will minimise death and disability among children zero to three years of age.