Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critica ....The contribution of human/marine herbivore interactions to reef degradation. This project aims to define how interactions between human society and herbivores influence marine ecosystem structure and function. It will analyse geographic patterns from recent systematic sampling of reef communities worldwide and study fish, macro-invertebrate and meso-grazer herbivory to identify herbivores’ role in the collapse and recovery of reef ecosystems. This project will examine the match between a critical ecosystem function and community structure across local to global scales, including the identification of non-linearities and interactions involving human effects on this process. This research is expected to safeguard marine ecosystems from collapse.Read moreRead less