Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100120
Funder
Australian Research Council
Funding Amount
$800,000.00
Summary
Dynamic Nuclear Polarisation system for molecular structure determination. Dynamic nuclear polarisation system for molecular structure determination:
This project aims to establish the first dynamic nuclear polarisation (DNP) spectrometer in Australia. DNP is designed to enhance the sensitivity of nuclear magnetic resonance techniques for molecular structure determination. The instrumentation would enable advancements in the biological and material sciences by providing enhanced sensitivity to ....Dynamic Nuclear Polarisation system for molecular structure determination. Dynamic nuclear polarisation system for molecular structure determination:
This project aims to establish the first dynamic nuclear polarisation (DNP) spectrometer in Australia. DNP is designed to enhance the sensitivity of nuclear magnetic resonance techniques for molecular structure determination. The instrumentation would enable advancements in the biological and material sciences by providing enhanced sensitivity to allow biomolecular and in-cell structure determination and the characterisation of new advanced materials. The facility is expected to drive interdisciplinary research and bring together scientific expertise that will accelerate advances in biomedical science, biochemistry, forensic science and security, polymers and nano-electronics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100141
Funder
Australian Research Council
Funding Amount
$310,000.00
Summary
High resolution nuclear magnetic resonance spectroscopy for glycomics, metabonomics and soft materials applications. This project will enhance the nuclear magnetic resonance spectroscopy capabilities and the world class research being undertaken at the Institute for Glycomics, Griffith University and Queensland University of Technology. This powerful technique can contribute information in diverse research areas such as glycomics, metabonomics and soft materials research.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE140100087
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Advanced Macromolecular Materials Characterisation Facility (AMMCF). Advanced macromolecular materials characterisation facility: The facility will allow precise characterisation of (bio)macromolecular materials, from chemical structures and composition as a function of size or biodistribution, to film thickness in multi-layer materials, to material hydrophobicity and permeability. Novel information derived from these state-of-the-art instruments is highly valuable in understanding structure-pro ....Advanced Macromolecular Materials Characterisation Facility (AMMCF). Advanced macromolecular materials characterisation facility: The facility will allow precise characterisation of (bio)macromolecular materials, from chemical structures and composition as a function of size or biodistribution, to film thickness in multi-layer materials, to material hydrophobicity and permeability. Novel information derived from these state-of-the-art instruments is highly valuable in understanding structure-property relationships, which are crucial for the development of the next generation of advanced materials with applications in electronics, optics, sensors, membranes, nanocoatings, biomaterials and polymer therapeutics. This facility underpins the efforts of the participating institutes in increasing the quality and quantity of research outcomes.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE170100701
Funder
Australian Research Council
Funding Amount
$354,224.00
Summary
Towards real-time image processing in single-particle electron microscopy. This project aims to research real-time image processing of single-particle electron microscopy (SPEM) images and to study structural dynamics in both biology and materials science. SPEM is an essential tool to study the structure and dynamics of nanoscale molecules. However, the theoretical frameworks underpinning SPEM are in their early stages of development. This research is expected to enable the study of colloidal na ....Towards real-time image processing in single-particle electron microscopy. This project aims to research real-time image processing of single-particle electron microscopy (SPEM) images and to study structural dynamics in both biology and materials science. SPEM is an essential tool to study the structure and dynamics of nanoscale molecules. However, the theoretical frameworks underpinning SPEM are in their early stages of development. This research is expected to enable the study of colloidal nanoparticle structures in solution and reveal the protein rearrangements that underlie secretion of bacterial proteins in two different systems a number of different bacterial species require for viability and infection.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100023
Funder
Australian Research Council
Funding Amount
$650,000.00
Summary
Australian high field electron paramagnetic resonance facility. This project aims to establish Australia’s first a high-field (3 T, 94 GHz) high-field pulse electron paramagnetic resonance (EPR) facility. EPR is a powerful technique to study chemical, biological and materials systems. It represents a sensitive, non-invasive, site-selective spectroscopy for the analysis of both molecular and macroscopic properties. This facility will allow the further development and implementation of new multidi ....Australian high field electron paramagnetic resonance facility. This project aims to establish Australia’s first a high-field (3 T, 94 GHz) high-field pulse electron paramagnetic resonance (EPR) facility. EPR is a powerful technique to study chemical, biological and materials systems. It represents a sensitive, non-invasive, site-selective spectroscopy for the analysis of both molecular and macroscopic properties. This facility will allow the further development and implementation of new multidimensional pulse EPR techniques, enabling domestic and international collaborations with diverse applications in structural biology, solvation science and catalysis.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100096
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behave ....A unique soft matter high-performance scanning probe microscopy (HP-SPM) facility. Soft matter research touches every aspect of our lives as it covers materials from the range of plastics found in cars, television sets and other mass-manufactured products, to new medical materials for tissue engineering and sensors. The proposed facility will enable Australia's leading scientists in this area to understand better how soft matter, including both biological and new advanced soft materials, behaves on the nano-scale level. This will put Australian researchers and engineers in a leading position for developing new treatments against cancer and other diseases, as well as harnessing the power of biology for application in areas such as waste treatment and energy production.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100168
Funder
Australian Research Council
Funding Amount
$1,235,000.00
Summary
Adelaide Nuclear Magnetic Resonance (NMR). Nuclear Magnetic Resonance (NMR) spectroscopy is a fundamental underpinning technology for the advancement of the many sciences which require determination of the structure of molecules. This project will significantly enhance and broaden NMR capabilities in South Australia and advance world-class research in chemistry, materials science, nanotechnology and biochemistry.
Intracellular lipid binding proteins as gatekeepers of drug activity. This project will explore the mechanisms by which drug molecules interact with lipid transport pathways within cells. The data obtained will provide a framework for the design of a new generation of drug candidates which have the potential to hijack intracellular transport pathways as a mechanism of targeted delivery to their sites of action.