Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989541
Funder
Australian Research Council
Funding Amount
$1,000,000.00
Summary
High Field Solid State and Multinuclear NMR Spectrometer for Structure/Function Analysis of Materials. Projects requiring the proposed infrastructure are aligned with two of the National Research Priorities. The research will lead to the development of novel materials, polymers and drugs, in particular nanoporous molecular frameworks, as well as reactive catalysts. The understanding of protein structure, disease and metabolic pathways which will be established using the proposed equipment will c ....High Field Solid State and Multinuclear NMR Spectrometer for Structure/Function Analysis of Materials. Projects requiring the proposed infrastructure are aligned with two of the National Research Priorities. The research will lead to the development of novel materials, polymers and drugs, in particular nanoporous molecular frameworks, as well as reactive catalysts. The understanding of protein structure, disease and metabolic pathways which will be established using the proposed equipment will contribute to the priority area 'Promoting and Maintaining Good Health'. In addition, the new equipment will extend capabilities and postgraduate training in chemistry, nanotechnology, and biomedicine (the priority area of 'Frontier Technologies for Building and Transforming Australian Industries').Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560751
Funder
Australian Research Council
Funding Amount
$432,474.00
Summary
Facility for the Analysis of Biomacromolecular Interactions. A facility for the analysis of biological macromolecules and their interactions with ligand molecules is required to support a large number of research projects in high priority areas including mechanisms of aging, drug development and bio/nanotechnology at three different universities. The instrumentation will (i) afford quantitative measurements of binding affinities between biological and chemical macromolecules, which are available ....Facility for the Analysis of Biomacromolecular Interactions. A facility for the analysis of biological macromolecules and their interactions with ligand molecules is required to support a large number of research projects in high priority areas including mechanisms of aging, drug development and bio/nanotechnology at three different universities. The instrumentation will (i) afford quantitative measurements of binding affinities between biological and chemical macromolecules, which are available only in small quantities, and small, drug related molecules (by microcalorimetry and dual polarization interferometry), and (ii) provide equipment necessary for sample characterization and purification prior to quantitative measurements (CD spectroscopy, and FPLC equipment).Read moreRead less
The Language of Knowledge. Knowledge is central to our lives. The way we attribute knowledge to others governs whom we trust, how we reason, what we do, and whether we succeed. The significance of this project consists in a deeper understanding of our attributions of knowledge, situated within the context of questions. This project offers the benefits of quality foundational research in an interdisciplinary venue. It connects to a range of areas of National Research Priority including An Environ ....The Language of Knowledge. Knowledge is central to our lives. The way we attribute knowledge to others governs whom we trust, how we reason, what we do, and whether we succeed. The significance of this project consists in a deeper understanding of our attributions of knowledge, situated within the context of questions. This project offers the benefits of quality foundational research in an interdisciplinary venue. It connects to a range of areas of National Research Priority including An Environmentally Sustainable Australia, Promoting and Managing Good Health, and Frontier Technologies for Building and Transforming Australian Industries, insofar as all of these areas of National Research Priority are concerned with the acquisition and transfer of knowledge.Read moreRead less
Perception, interpretation, and the explanation of delusional beliefs. The occurrence of bizarrely false beliefs, called delusions, presents challenges, not only for clinical psychiatric practice, but also for psychology, neuroscience, and philosophy. The aim of this project is to make a distinctively philosophical contribution to our understanding of delusional beliefs by addressing three philosophical questions raised by the study of delusions, questions about perception, interpretation, and e ....Perception, interpretation, and the explanation of delusional beliefs. The occurrence of bizarrely false beliefs, called delusions, presents challenges, not only for clinical psychiatric practice, but also for psychology, neuroscience, and philosophy. The aim of this project is to make a distinctively philosophical contribution to our understanding of delusional beliefs by addressing three philosophical questions raised by the study of delusions, questions about perception, interpretation, and explanation. Answers to these questions will constitute substantial contributions to three central areas of philosophy, but their significance also extends beyond philosophy. They will impact on the scientific investigation of delusions and will contribute indirectly to the treatment and rehabilitation of sufferers.
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Epistemic Warrant: Transmission Failure, Basic Knowledge, and Entitlement. This Project will bring substantial intellectual, cultural, and economic benefits to the nation - not only by increasing research strength, contributing to research output and establishing an international research partnership, but also by deepening the relationship between the study of the mind and theory of knowledge as a traditional area within philosophy and thus helping to maintain the pivotal position of philosophy ....Epistemic Warrant: Transmission Failure, Basic Knowledge, and Entitlement. This Project will bring substantial intellectual, cultural, and economic benefits to the nation - not only by increasing research strength, contributing to research output and establishing an international research partnership, but also by deepening the relationship between the study of the mind and theory of knowledge as a traditional area within philosophy and thus helping to maintain the pivotal position of philosophy in our intellectual life. Students, early-career researchers and established philosophers will benefit from access to the intellectual and institutional resources of international partner universities and there will be substantial and quantifiable financial contributions by international universities and research agencies.Read moreRead less
Evolvability and the Evolution of Complexity. Anyone engaging in a moment's reflection on the striking richness, diversity, and complexity of the biological world is faced with the question: how did it get here? Though natural selection is central to answering this question, important new work has identified various conditions that make some lineages of organisms "evolvable": capable of changing in ways that radically expand the range of further possible changes. This project will clarify and in ....Evolvability and the Evolution of Complexity. Anyone engaging in a moment's reflection on the striking richness, diversity, and complexity of the biological world is faced with the question: how did it get here? Though natural selection is central to answering this question, important new work has identified various conditions that make some lineages of organisms "evolvable": capable of changing in ways that radically expand the range of further possible changes. This project will clarify and integrate these various conditions using empirical examples and simple models. The resulting work from this project will provide a clearer general understanding of what biological complexity is, and how science has compelling candidates for understanding how it evolves.Read moreRead less
Reasons and Rationality. The project explains how we assess the truth and falsehood of everyday claims about what people have reason to do. It also explains what legitimizes our practice of praising and blaming people for their success and failure at doing what we think they have reason to do. In so doing it provides a foundation for both our ordinary practice of holding people responsible, and for the more institutionalised counterpart of this ordinary practice in the law.
Understanding phenomenal experience as a natural part of our world. The natural sciences?physics, chemistry and biology?provide compelling accounts of our world. They contain, however, no overt mention of mental states and in particular the mental states with a phenomenology: states like itches and colour experiences. The challenge for naturalists is locate these states within the naturalist picture. This project develops and draws on representationalist accounts of mind to explain how to locate ....Understanding phenomenal experience as a natural part of our world. The natural sciences?physics, chemistry and biology?provide compelling accounts of our world. They contain, however, no overt mention of mental states and in particular the mental states with a phenomenology: states like itches and colour experiences. The challenge for naturalists is locate these states within the naturalist picture. This project develops and draws on representationalist accounts of mind to explain how to locate mental states that have a phenomenology within the naturalist's picture. This will yield new perspectives on the mental lives of machines.Read moreRead less
Conscious Experience and the Hegemony of Representation. Many things make humans special but three stand out: the possession of a moral sense, rationality, and consciousness. This project aims to explain consciousness in a way fully comppatible with the aspirations of cognitive science to see humans as a natural part of the physical world.
Belief singular versus beliefs plural. Research on the brain and how it represents the environment has the potential to reconfigure our ordinary conceptions of belief and rationality. This project explores the impact of the changes and their implications.