The National Survey of Adult Oral Health will interview and dentally examine 7,500 people aged 15 or more across all States and Territories of Australia. It will provide a national snap-shot of the nation's oral health, including levels of tooth loss, dental decay and gum disease. The survey, to be conducted in 2004-04, will be directed by researchers at the Australian Research Center for Population Oral Health at The University of Adelaide. It will be conducted in collaboration with the Commonw ....The National Survey of Adult Oral Health will interview and dentally examine 7,500 people aged 15 or more across all States and Territories of Australia. It will provide a national snap-shot of the nation's oral health, including levels of tooth loss, dental decay and gum disease. The survey, to be conducted in 2004-04, will be directed by researchers at the Australian Research Center for Population Oral Health at The University of Adelaide. It will be conducted in collaboration with the Commonwealth and State-Territory health departments. Occurring 17 years after the first National Oral Health Survey of Australia, this new survey will monitor changes in oral health among all Australians. The survey will identify groups at particular disadvantage in terms of oral diseases, and it will search for lifestyle and community-level hazards that increase the risk of oral disorders. The study will have a compare patterns of dental health among people born before and after the fluoride generation of adults born in the 1960s when most of Australia's capital city water supplies became fluoridated. The study has been designed to automatically capture national statistics on general health among the 7,500 study participants over the next decade. The researchers will use that information to study links that have been observed in other countries between gum disease and heart disease. Results from the survey will provide the basis for monitoring progress towards national health targets and provide information to help direct dental health services into the 21st century.Read moreRead less
Chronic Gastrointestinal Symptoms And Diabetes Mellitus: Risk Factors And Mechanisms
Funder
National Health and Medical Research Council
Funding Amount
$271,527.00
Summary
Why many people with diabetes mellitus are afflicted by gastrointestinal (GI) symptoms remains uncertain. Irreversible damage to the nerves controlling the gut (autonomic neuropathy) is often considered to be important. An alternative cause of increased GI symptomatology in diabetics is poor glucose control. Some studies have shown that acute shifts in glucose levels induce changes in the gut relevant to the onset of GI symptoms. For example, high glucose levels acutely cause slower stomach empt ....Why many people with diabetes mellitus are afflicted by gastrointestinal (GI) symptoms remains uncertain. Irreversible damage to the nerves controlling the gut (autonomic neuropathy) is often considered to be important. An alternative cause of increased GI symptomatology in diabetics is poor glucose control. Some studies have shown that acute shifts in glucose levels induce changes in the gut relevant to the onset of GI symptoms. For example, high glucose levels acutely cause slower stomach emptying times, leading to feelings of fullness. Though the effects of chronic glucose levels are yet to be properly explored, population data show that poor control in the long-term is related to an increase in symptoms. The aim of this prospective study is to determine the roles played by both autonomic neuropathy and glucose control in the development of GI symptoms among diabetics. All past research has been cross-sectional, and so cannot tell us if one or both of these factors cause GI problems in diabetes. For example, it is possible that autonomic neuropathy causes an increase in GI symptoms such as nausea and fullness, which in turn induces poor glucose control though lack of appetite or inadequate stomach emptying. Upon study inclusion, all study participants will undergo a series of autonomic tests. At 3 month intervals for a period of 30 months, they will be asked to complete a 2-week diary card detailing their GI symptoms and glucose readings, and also supply blood and urine samples for analysis twice each year. Two years from the study outset, participants will again complete the autonomic test series. Psychiatric co-morbidity will be investigated using the Composite Diagnostic Interview (CIDI-Auto) at the autonomic testing time points. The study will be undertaken at the Gastroenterology Research Unit at Nepean Hospital, in collaboration with the Royal Adelaide Hospital, centres with proven track records in diabetes investigation.Read moreRead less