Skin penetration of nanoparticles promoted by particle design, formulation and application method. This project seeks to better define the determinants of nanoparticle skin penetration and subsequent disposition in the body. The data would be used to guide minimal skin penetration of 'undesirable' nanoparticles and the properties required of 'safe' nanoparticles to enable effective human skin delivery in cosmetic and dermatological products.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100187
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
SA Facility for High Resolution Imaging and Material Characterization. Facility for high resolution imaging and material characterisation: The aim of this project is to establish a facility that will allow researchers to visualise and analyse structure at nanoscale resolutions. The development of the next generation of opto-electronics, electrochemical and biomedical devices requires tools that can quickly visualise and characterise complex materials at multiscale. The new collaborative nano in ....SA Facility for High Resolution Imaging and Material Characterization. Facility for high resolution imaging and material characterisation: The aim of this project is to establish a facility that will allow researchers to visualise and analyse structure at nanoscale resolutions. The development of the next generation of opto-electronics, electrochemical and biomedical devices requires tools that can quickly visualise and characterise complex materials at multiscale. The new collaborative nano infrared thermal analysis facility is essential to meet the demands of a large number of innovative projects conducted by multidisciplinary consortia of researchers. Located in state-of-the art laboratories and managed as open access resources, the facility will enable and advance research in the areas of energy harvesting, environmental monitoring, biomedical devices, food and pharmaceuticals.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101044
Funder
Australian Research Council
Funding Amount
$444,318.00
Summary
Bio-inspired nanomaterials with tunable drug loading and controlled release. This project aims to develop new platform technologies for making bio-inspired nanomaterials with tunable drug loading and controlled release. This project will revolutionise current approaches to make lipid nanoparticles camouflaged with natural cell membranes for delivery of both insoluble and soluble drugs. Significant outcomes will include a novel commercially relevant salt-induced nanoprecipitation platform technol ....Bio-inspired nanomaterials with tunable drug loading and controlled release. This project aims to develop new platform technologies for making bio-inspired nanomaterials with tunable drug loading and controlled release. This project will revolutionise current approaches to make lipid nanoparticles camouflaged with natural cell membranes for delivery of both insoluble and soluble drugs. Significant outcomes will include a novel commercially relevant salt-induced nanoprecipitation platform technology for making precisely engineered nanomaterials with tailored functions for applications in controlled release and targeted delivery. Benefits include securing a sustainable future for Australia, with new nanotechnology strategies for advanced manufacturing.Read moreRead less
Artificial photosynthesis for solar fuel production. We aim to realise an artificial system that converts solar energy to hydrogen (artificial photosynthesis). The resulting device will be able to 'split' water into oxygen and hydrogen, whereas hydrogen can be further converted into electricity or heat (combustion).
Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipi ....Precision-engineered hybrid core-shell materials . This project aims to develop new platform technologies for making nanostructured hybrid core-shell materials with exceptionally high drug loading and programmed release. Building on this research team's recent breakthrough in the precision engineering of core-shell materials, this research will revolutionise current approaches for making drug-loaded polymer and inorganic particles. Significant outcomes will include a novel sequential nanoprecipitation platform technology for making drug-core polymer-shell nanoparticles, and a new bio-inspired approach for making hybrid drug-core silica-shell nanocomposites, and new materials for applications in programmed release and delivery systems.Read moreRead less
Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230101011
Funder
Australian Research Council
Funding Amount
$420,818.00
Summary
Developing advanced potassium-sulfur batteries for scalable energy storage. Potassium-sulfur (K-S) batteries are recognised as a promising energy storage technology for large-scale applications, due to their high theoretical capacity, low toxicity and the low cost of both potassium and sulfur. However, their grid-scale development is plagued by safety hazards and fast capacity fade. This project aims to address these challenges by developing atomic-level engineering of host materials for sulfur, ....Developing advanced potassium-sulfur batteries for scalable energy storage. Potassium-sulfur (K-S) batteries are recognised as a promising energy storage technology for large-scale applications, due to their high theoretical capacity, low toxicity and the low cost of both potassium and sulfur. However, their grid-scale development is plagued by safety hazards and fast capacity fade. This project aims to address these challenges by developing atomic-level engineering of host materials for sulfur, K metal anode and solid electrolyte. The outcomes of this project will provide increased understanding of the mechanism for K-S batteries and novel strategies for their development, placing Australia at the forefront of K-S batteries for scalable battery research and supporting our cutting-edge energy storage technology.
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Tailoring physiologically-based nanomaterial fertilisers for the biofortification of zinc in broadacre crops. Soil zinc deficiency is a global issue causing low crop yield and malnutrition. This project will develop a new class of fertiliser formulations by combining advanced chemistry techniques with plant physiology knowledge and nanomaterial manufacturing. These products will be designed for enhanced agronomic efficiency and environmental safety.
Discovery Early Career Researcher Award - Grant ID: DE230100324
Funder
Australian Research Council
Funding Amount
$394,318.00
Summary
Cooperative Single Atom Catalysts for Zn-CO2 Batteries. This project aims to develop cooperative single-atom catalysts for efficient and selective electrocatalytic CO2 conversion and Zn-CO2 batteries. Cooperative catalysts at the single atom limit can potentially achieve enhanced electrochemical properties beyond state-of-the-art and will trigger significant theoretical and technological interests in energy conversion and storage fields. It is expected to generate new knowledge in materials scie ....Cooperative Single Atom Catalysts for Zn-CO2 Batteries. This project aims to develop cooperative single-atom catalysts for efficient and selective electrocatalytic CO2 conversion and Zn-CO2 batteries. Cooperative catalysts at the single atom limit can potentially achieve enhanced electrochemical properties beyond state-of-the-art and will trigger significant theoretical and technological interests in energy conversion and storage fields. It is expected to generate new knowledge in materials science and electrochemistry, using interdisciplinary approaches of atom-precise material engineering, in situ characterisation and full-cell optimisation. Significant economic and environmental benefits are expected from developing carbon-neutral CO2 electrolysers with low cost and high energy efficiency.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200101244
Funder
Australian Research Council
Funding Amount
$417,276.00
Summary
Advanced zinc-ion batteries with high voltage and high energy density. Zinc-ion battery is not only cheaper than current lithium-ion battery (LIB), but it is safer due to a neutral aqueous electrolyte. However, its grid-scale development is plagued by limited output voltage and inadequate energy density compared with more mainstream LIB. This project aims to solve the discharge-voltage problem by fabricating atomic-level structure engineered manganese (Mn)-based cathode and a new stable solid-st ....Advanced zinc-ion batteries with high voltage and high energy density. Zinc-ion battery is not only cheaper than current lithium-ion battery (LIB), but it is safer due to a neutral aqueous electrolyte. However, its grid-scale development is plagued by limited output voltage and inadequate energy density compared with more mainstream LIB. This project aims to solve the discharge-voltage problem by fabricating atomic-level structure engineered manganese (Mn)-based cathode and a new stable solid-state electrolyte, and improve the device energy density by zinc (Zn) anode interface nanotechnology. The success of this project will benefit Australia’s access to new markets and introduce a new low-cost and safe energy storage technology for the long-term viability of Australia’s abundant Zn and Mn resources.Read moreRead less