Readying Wireless Networks for Future Communications Systems: From Ubiquitous Computing to the Internet of Things. This project aims to prepare wireless networks for future communications systems, by improving the data transmission rates of wireless networks, through developing new coding schemes based on the synergy of noisy-channel coding and index coding. This will allow wireless networks, used in conjunction with the fibre-optic National Broadband Network, to support future high-data-rate an ....Readying Wireless Networks for Future Communications Systems: From Ubiquitous Computing to the Internet of Things. This project aims to prepare wireless networks for future communications systems, by improving the data transmission rates of wireless networks, through developing new coding schemes based on the synergy of noisy-channel coding and index coding. This will allow wireless networks, used in conjunction with the fibre-optic National Broadband Network, to support future high-data-rate and ubiquitous communication services. This project aims to produce new theoretical results in the field of communication theory, and efficient practical coding schemes for wireless communications.Read moreRead less
Data sharing with strong privacy against inference attacks. This project aims to develop theories and techniques for strong protection of personal information in sharing large datasets such as national health data or census records. It intends to achieve this through developing new information theoretic methods for synthesising datasets with proven high fidelity and protection against re-identification and inference attacks, where attackers try to learn probability of sensitive data. The expecte ....Data sharing with strong privacy against inference attacks. This project aims to develop theories and techniques for strong protection of personal information in sharing large datasets such as national health data or census records. It intends to achieve this through developing new information theoretic methods for synthesising datasets with proven high fidelity and protection against re-identification and inference attacks, where attackers try to learn probability of sensitive data. The expected outcomes are algorithms for public and private sector data curators to dial up or down their data access arrangements based on privacy risks and fidelity demands linked with different data types and uses. This project intends to enable Australians to securely benefit from valuable data in decision making.Read moreRead less
Harnessing light and electricity to drive chemical synthesis. This project will explore and establish original strategies that use inputs of energy (light and electricity) to break or form chemical bonds, which can provide new or improved access to valuable compounds. In this way, this research will augment or enhance existing methods for the selective and direct manipulation of molecules by creating tools that allow chemists to prepare molecules under particularly mild conditions. The outcomes ....Harnessing light and electricity to drive chemical synthesis. This project will explore and establish original strategies that use inputs of energy (light and electricity) to break or form chemical bonds, which can provide new or improved access to valuable compounds. In this way, this research will augment or enhance existing methods for the selective and direct manipulation of molecules by creating tools that allow chemists to prepare molecules under particularly mild conditions. The outcomes of the project will include the development of new technology for organic synthesis and forging novel approaches for chemical alkylation and cross-coupling reactions. This can contribute to making important compounds more efficiently, safely and cheaper to produce in the future.Read moreRead less
Novel organic architectures and functional materials from tropylium ions. This project aims to develop new synthetic applications of tropylium ions, as versatile building blocks, to access a broad range of organic structures that used to be difficult and problematic to synthesise. The non-benzenoid aromatic tropylium ion exhibits a unique combination of structural stability and chemical reactivity. This project expects to use tropylium ions as chromophores to derive novel ‘push-and-pull’ organic ....Novel organic architectures and functional materials from tropylium ions. This project aims to develop new synthetic applications of tropylium ions, as versatile building blocks, to access a broad range of organic structures that used to be difficult and problematic to synthesise. The non-benzenoid aromatic tropylium ion exhibits a unique combination of structural stability and chemical reactivity. This project expects to use tropylium ions as chromophores to derive novel ‘push-and-pull’ organic dyes with highly applicable physicochemical properties.This will provide access to a family of novel complex organic structures in a new chemical space, as well as new materials for opto-electronic and sensing applications, respectively.Read moreRead less
Next Generation Photocatalysis for Chemical Synthesis and Manufacture. This project aims to discover new methods for the activation of energy demanding bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the development of multiphoton photoredox catalysis as a powerful tool to activate traditionally unreactive, yet abundant chemical bonds in organic molecules including C-H bonds in alkane and olefin feedstocks. With application in f ....Next Generation Photocatalysis for Chemical Synthesis and Manufacture. This project aims to discover new methods for the activation of energy demanding bonds in organic molecules as a general strategy in chemical synthesis. A key conceptual advance in this project is the development of multiphoton photoredox catalysis as a powerful tool to activate traditionally unreactive, yet abundant chemical bonds in organic molecules including C-H bonds in alkane and olefin feedstocks. With application in fields that range from fine chemical production to drug discovery, the overarching aim of this research is to establish new bond activation reactions and to demonstrate translations to the invention of new pharmaceuticals, agrochemicals and advanced chemical manufacturing processes that will have societal impact.Read moreRead less
Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Synthesis and Fundamental Understanding of Low-Dimensional Metal Oxide Nanoparticles for Gas Sensing Application. This project is primarily devoted to material science and nanotechnology, one of the cutting-edge areas in Australia's National Research Priority. Successful completion of this project will result in controlled synthesis, functional assembly and fundamental understanding of low-dimensional metal oxide nanostructures. The research findings will be useful for developing new and complex ....Synthesis and Fundamental Understanding of Low-Dimensional Metal Oxide Nanoparticles for Gas Sensing Application. This project is primarily devoted to material science and nanotechnology, one of the cutting-edge areas in Australia's National Research Priority. Successful completion of this project will result in controlled synthesis, functional assembly and fundamental understanding of low-dimensional metal oxide nanostructures. The research findings will be useful for developing new and complex nanostructures for functional applications in lithium ionic batteries, catalysts and gas sensors. The conduct of this project will significantly expand the knowledge creativity of Australia in advanced materials.
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Using natural products to inspire discoveries in synthesis and biosynthesis. This project aims to understand the organic chemistry that occurs in the biosynthesis of unusual antibiotic natural products by marine microorganisms. In an interdisciplinary approach, proposed biosynthetic intermediates will be synthesised and screened against newly isolated enzymes from the microorganisms of interest. This will allow the elucidation of biosynthetic pathways, and aid the discovery of new chemoenzymatic ....Using natural products to inspire discoveries in synthesis and biosynthesis. This project aims to understand the organic chemistry that occurs in the biosynthesis of unusual antibiotic natural products by marine microorganisms. In an interdisciplinary approach, proposed biosynthetic intermediates will be synthesised and screened against newly isolated enzymes from the microorganisms of interest. This will allow the elucidation of biosynthetic pathways, and aid the discovery of new chemoenzymatic reactivity that may be broadly useful in organic synthesis. Non-enzymatic, predisposed organic reactions will also be uncovered during the project. The benefit of this project will be an improvement in our ability to synthesise potential antibiotics using a combined synthetic organic and chemoenzymatic approach. This could lead to useful new antibiotics in the future.Read moreRead less
Internally decorated discrete Metallo-supramolecular Assemblies and infinite Metal-Organic Frameworks as molecular containers. In the macroscopic world, containers are used to hold, provide physical protection, or create a modified environment for their contents. This project will result in the synthesis of novel molecular container materials that provide decorated internal surfaces capable of selectively binding chemical species. In addition to the breakthrough scientific benefits of establish ....Internally decorated discrete Metallo-supramolecular Assemblies and infinite Metal-Organic Frameworks as molecular containers. In the macroscopic world, containers are used to hold, provide physical protection, or create a modified environment for their contents. This project will result in the synthesis of novel molecular container materials that provide decorated internal surfaces capable of selectively binding chemical species. In addition to the breakthrough scientific benefits of establishing the fundamentals of these systems, the binding of chemicals, which are environmental contaminants, will provide the grounding for applications that will contribute to the national priority of 'Frontier technologies'. Furthermore, this research will lead to the training of the next generation of Australian scientists by quality international researchers.Read moreRead less
Extending the frontiers of organocatalysis: new reactions involving nucleophilic carbenes. High technology solutions to the problems of today and tomorrow require new materials designed for specific activities. This project will deliver new technologies for the rapid and efficient assembly of materials designed for function.