Dendritic Organic Semiconductors. This Federation Fellowship, along with the creation of a Centre for Organic Semiconductor Research at The University of Queensland will enable Australian science to have a high profile in organic semiconductors. This is an important scientific and technological goal and the research programme will provide expertise for industry in Australia as well as potentially creating technologies for new industry. It will also provide a focus for other academic institutions ....Dendritic Organic Semiconductors. This Federation Fellowship, along with the creation of a Centre for Organic Semiconductor Research at The University of Queensland will enable Australian science to have a high profile in organic semiconductors. This is an important scientific and technological goal and the research programme will provide expertise for industry in Australia as well as potentially creating technologies for new industry. It will also provide a focus for other academic institutions in Australia by bringing together people with the requisite expertise in materials preparation, characterisation, modelling, photophysics, and device physics and engineering. Read moreRead less
Engineering Nanostructured Bio-inspired Products. New nanostructured products that draw on biology promise to revolutionise our lives and economy. Designer emulsions and self-assembling particles inspired by viruses are two such products that form the focus for this research programme. The constitutive behaviour of bio-molecular films that control emulsion performance will be characterised and linked to molecular properties and manufacturing conditions. A broad-based technology platform for t ....Engineering Nanostructured Bio-inspired Products. New nanostructured products that draw on biology promise to revolutionise our lives and economy. Designer emulsions and self-assembling particles inspired by viruses are two such products that form the focus for this research programme. The constitutive behaviour of bio-molecular films that control emulsion performance will be characterised and linked to molecular properties and manufacturing conditions. A broad-based technology platform for the in vitro creation of self-assembling biological nanoparticles will also be developed. Key outcomes will be valuable IPR and fundamental engineering science knowledge to ensure that the value chain for this class of products can deliver commercial outcomes.Read moreRead less
Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome proje ....Beyond Microarrays: Nano-Scaled Devices for High Throughput Biomolecular Sensing. Current developments in Nanoscience and Nanotechnology hold many promises in terms of revolutionising our industrial base, transforming biology, medical science and practice. This project strives to achieve some of these aims by, for the first time, building and testing nano-scaled devices with the capability to 'read' massive amounts of biological information. With the recent completion of the Human Genome project, major opportunities exist to provide spectacular advances in human health care (eg, via personalised medicine) provided that appropriate high-throughput biological reading devices can be developed. In developing such devices, this project also aims to substantially catalyse the Australian Nanotechnology/Biotechnology industry.Read moreRead less
Self organization in (bio)molecular systems: Simulating the folding and aggregation of peptides, proteins and lipids. Molecular self-assembly is a basic property of living systems. Most proteins fold spontaneously and then further self-organize into functional complexes, effectively biological machines. Understanding how this occurs is a fundamental theoretical challenge with widespread application. Work will focus on developing methodology to simulate, computationally, the folding and aggrega ....Self organization in (bio)molecular systems: Simulating the folding and aggregation of peptides, proteins and lipids. Molecular self-assembly is a basic property of living systems. Most proteins fold spontaneously and then further self-organize into functional complexes, effectively biological machines. Understanding how this occurs is a fundamental theoretical challenge with widespread application. Work will focus on developing methodology to simulate, computationally, the folding and aggregation of peptides, proteins, and lipids. The aim is to accurately predict the structures of small peptides in solution and to refine crude models of larger molecules (complexes). This will facilitate the development of peptide based therapeutics and is essential in exploiting the growing volume of genetic information in biology and medicine.Read moreRead less
Chemical Mimics Of Bioactive Protein Surfaces. Frontier chemical technology will be developed and applied to construction of new compounds that mimic unstable fragments of bioactive protein surfaces. New materials can contribute to National Research Priorities by presenting new ways of impacting on infection, diseases of the aged, and preventative medicine (drugs, vaccines, diagnostics). The technology and materials will advance basic science at the chemistry-biology interface; permit new applic ....Chemical Mimics Of Bioactive Protein Surfaces. Frontier chemical technology will be developed and applied to construction of new compounds that mimic unstable fragments of bioactive protein surfaces. New materials can contribute to National Research Priorities by presenting new ways of impacting on infection, diseases of the aged, and preventative medicine (drugs, vaccines, diagnostics). The technology and materials will advance basic science at the chemistry-biology interface; permit new applications in medicine, science and industry; present new economic opportunities for building and strengthening Australian companies; attract and train outstanding young people in interdisciplinary science; and enhance the international reputation of Australian science and technology.Read moreRead less