Energetics and dynamics of solvated biologically relevant molecules using liquid microjet and ion imaging technologies. The shape of many biomolecules in solution plays a critical role in determining their biological activity and function. It is known that the bonds that form between the biomolecules and the water solvent control this shape. However, very little is known about the strength and structure of these bonds at different sites around the biomolecule. Many experiments have informed u ....Energetics and dynamics of solvated biologically relevant molecules using liquid microjet and ion imaging technologies. The shape of many biomolecules in solution plays a critical role in determining their biological activity and function. It is known that the bonds that form between the biomolecules and the water solvent control this shape. However, very little is known about the strength and structure of these bonds at different sites around the biomolecule. Many experiments have informed us about the strength of the bonds, others have told us where the bonds occur. This project will provide both pieces of information for the first time, allowing us to better understand, and therefore control, biological function. This work will assist in the development of new biotechnology processes, especially in the emerging area of proteomics.Read moreRead less
Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lip ....Correlative Imaging of Brain Lipids. This project aims to develop imaging tools and protocols for the detection of lipids in brain tissue and cells. This project expects to generate advanced methodologies to display specific lipid classes and their corresponding structures within tissues and cells, with the ability to be detected and correlated with multiple techniques, which represent a currently unavailable capacity. The expected outcomes of this project are improved opportunities to study lipid biology at the cellular and sub-cellular level across a wide range of in vitro and in vivo models. The outcomes of this project should provide significant knowledge to tackle modern societal challenges in healthy ageing, brain pathologies and neurodegenerative diseases.Read moreRead less
Resilience in biogeochemical pathways along a catchment-to-coast continuum. Aquatic systems have degraded more in the past 50 years than any other time in history. Global pressures are further threatening their sustainability, but their complexity makes it difficult to understand how they are responding. This project will combine numerous state-of-the-art approaches to unravel pathways that shape their response.
Smart self-propelled nanoreactors for catalytic environmental remediation. This project aims to develop nanomaterial design and technology to enable the applications of nanotechnology for environmental remediation. Various nanomotors with different asymmetric structures will be fabricated and tested for catalytic and photocatalytic degradation of aqueous pollutants. The physicochemical properties, motion behaviour and catalytic performance will be comprehensively investigated. The outcomes of th ....Smart self-propelled nanoreactors for catalytic environmental remediation. This project aims to develop nanomaterial design and technology to enable the applications of nanotechnology for environmental remediation. Various nanomotors with different asymmetric structures will be fabricated and tested for catalytic and photocatalytic degradation of aqueous pollutants. The physicochemical properties, motion behaviour and catalytic performance will be comprehensively investigated. The outcomes of the project will underpin the development of green technologies for sustainable energy conversion and water treatment. This will provide significant benefits, putting Australia in a leading position in the sustainable development of nanotechnology for sustainable energy supply and transformation as well as environmental and biomedical applications.Read moreRead less
Microbially induced calcium carbonate precipitation in different substrates. Carbonates in the form of limestone represent an important reservoir of carbon on earth. They are recorded in several natural geological formations as corals, stromatolites, beach rocks. Microbes play an important role in the formation as well as dissolution of carbonates during microbially induced calcium carbonate precipitation (MICP) reactions on different substrates in natural and built environments. Much of our kno ....Microbially induced calcium carbonate precipitation in different substrates. Carbonates in the form of limestone represent an important reservoir of carbon on earth. They are recorded in several natural geological formations as corals, stromatolites, beach rocks. Microbes play an important role in the formation as well as dissolution of carbonates during microbially induced calcium carbonate precipitation (MICP) reactions on different substrates in natural and built environments. Much of our knowledge on MICP is limited due to poor understanding of the reaction kinetics at a molecular level. This project will develop new methods to enable and advance the knowledge of MICP process with profound implications for understanding natural geological formations as well as widen the scope of current engineering applications.Read moreRead less
Integrated photo and thermal catalysis for economic carbon dioxide conversion to fuels. The project aims to develop an integrated process for simultaneously photo- and thermal-catalytic conversion of carbon dioxide and water vapour to hydrocarbon fuels and chemicals using solar light and waste heat from flue gas. This project will design and make multi-functional catalysts based on zirconium metal organic frameworks, incorporating quantum dots and metal nanoclusters. This project is expected to ....Integrated photo and thermal catalysis for economic carbon dioxide conversion to fuels. The project aims to develop an integrated process for simultaneously photo- and thermal-catalytic conversion of carbon dioxide and water vapour to hydrocarbon fuels and chemicals using solar light and waste heat from flue gas. This project will design and make multi-functional catalysts based on zirconium metal organic frameworks, incorporating quantum dots and metal nanoclusters. This project is expected to develop an advanced materials system, reduce carbon dioxide and use it to produce fuel, and harness solar energy. The project should advance Australia’s leading role in reducing carbon emission, and producing clean energy and nanotechnology.Read moreRead less
Helium recovery from liquefied natural gas waste stream using nanoporous mxene materials. The waste streams from many liquefied natural gas (LNG) industries still contains valuable helium, a possible next mineral to sustain our economic growth. This project aims to efficiently separate helium from methane and nitrogen via the layered two dimensional materials. This project will seek to understand the assembling behaviour of these nano-sized Mxene flakes and their molecular sieving properties. Au ....Helium recovery from liquefied natural gas waste stream using nanoporous mxene materials. The waste streams from many liquefied natural gas (LNG) industries still contains valuable helium, a possible next mineral to sustain our economic growth. This project aims to efficiently separate helium from methane and nitrogen via the layered two dimensional materials. This project will seek to understand the assembling behaviour of these nano-sized Mxene flakes and their molecular sieving properties. Australia is playing a leading role in the global liquefied natural gas (LNG) production and trade. This project expects to further position Australia at the forefront of intellectual leadership in the field of gas processing and material development. This will have significant benefits, such as further improving these LNG projects economics by cost-effectively producing helium as a valuable by-product via advanced porous nano-materials.Read moreRead less
Vortex fluidic mediated chemical transformations. This project aims to develop a continuous flow vortex fluidic device (VFD) for chemical and biochemical transformations. Vortex fluidic devices should lead to cleaner and faster ways of preparing complex molecules. Depending on the VFD’s operating parameters, including applying field effects such as Faraday waves, plasmas and light sources, reactions could have higher yields and selectivity than traditional batch processing. This will be translat ....Vortex fluidic mediated chemical transformations. This project aims to develop a continuous flow vortex fluidic device (VFD) for chemical and biochemical transformations. Vortex fluidic devices should lead to cleaner and faster ways of preparing complex molecules. Depending on the VFD’s operating parameters, including applying field effects such as Faraday waves, plasmas and light sources, reactions could have higher yields and selectivity than traditional batch processing. This will be translated into molecular assembly line syntheses in a single unit or a series. Such syntheses should provide a versatile toolbox for molecular transformations, under continuous flow conditions where scalability is addressed upfront. This will be attractive to industry and minimise effects on the environment.Read moreRead less
Modular Vortex Fluidic Mediated Molecular Transformations. The project aims to develop the use of electric and magnetic fields to control chemical and biochemical reactions in high shear thin films under readily scalable continuous flow conditions to then be able to precisely build complex functional molecules. Depending on the orientation, strength and frequency of external electric and magnetic fields, and novel shear stress induced electric fields in solution, rates of reactions can be enhanc ....Modular Vortex Fluidic Mediated Molecular Transformations. The project aims to develop the use of electric and magnetic fields to control chemical and biochemical reactions in high shear thin films under readily scalable continuous flow conditions to then be able to precisely build complex functional molecules. Depending on the orientation, strength and frequency of external electric and magnetic fields, and novel shear stress induced electric fields in solution, rates of reactions can be enhanced, with higher yields and tunable selectivity, and reduced waste and energy usage, which is not possible using traditional batch processing. This will be translated into molecular assembly line processing and the development of a new synthetic toolbox, with applications in preparing pharmaceuticals.
Read moreRead less
Controlling the organisation of matter using vortex fluidics. Vortex fluidic devices will be developed and used to construct functional complex molecules and materials, and probe the structure of self assembled systems. The scalable processing will be assessed for application in advanced materials production, the chemical industry and in developing complex molecules for drug discovery.