Robust fluid mixing through topological chaos. The Australian chemicals and plastics industry has an annual turnover of over $20 billion and employs over 77,000 people; fluid mixing is fundamental to this industry, yet the industry is recognised as underinvesting in research and development in this essential area. Furthermore, frontier technologies such as biotechnology and the next generation of smart materials also crucially rely on fluid mixing. This project aims to evaluate a new paradigm ( ....Robust fluid mixing through topological chaos. The Australian chemicals and plastics industry has an annual turnover of over $20 billion and employs over 77,000 people; fluid mixing is fundamental to this industry, yet the industry is recognised as underinvesting in research and development in this essential area. Furthermore, frontier technologies such as biotechnology and the next generation of smart materials also crucially rely on fluid mixing. This project aims to evaluate a new paradigm (topological chaos) for the design of mixers, to provide better and more robust mixers that work from microscopic to industrial scales.Read moreRead less
Structure and activity of host-defence peptides from Australian anurans: anticancer agents, neuropeptides and nNOS inhibitors. We have discovered peptides that may have clinical applications. This is significant as these molecules may have one or more of the following properties. They may have anti-cancer effects; they may increase the effectiveness of the immune system by enhancing lymphocyte formation; and, they may act to reduce inflammation, stroke or cardiac conditions by controlling nitri ....Structure and activity of host-defence peptides from Australian anurans: anticancer agents, neuropeptides and nNOS inhibitors. We have discovered peptides that may have clinical applications. This is significant as these molecules may have one or more of the following properties. They may have anti-cancer effects; they may increase the effectiveness of the immune system by enhancing lymphocyte formation; and, they may act to reduce inflammation, stroke or cardiac conditions by controlling nitric oxide formation. Another national benefit is that personnel involved in this project are trained to the highest international standards in peptide chemistry/mass spectrometry/nuclear magnetic resonance: currently, there are not enough trained scientists in this area to meet demand.Read moreRead less
Biologically active peptides and proteins from anurans: the relationship between structure and activity. We have identified peptides (from glands of frogs and toads), some of which are amongst the most powerful biologically active compounds in the animal kingdom. The aims of this project are to investigate the relationship between the structure and bioactivity of chosen groups of peptides including pheromones, anticancer and antibiotic peptides, and peptides which inhibit neuronal nitric oxide ....Biologically active peptides and proteins from anurans: the relationship between structure and activity. We have identified peptides (from glands of frogs and toads), some of which are amongst the most powerful biologically active compounds in the animal kingdom. The aims of this project are to investigate the relationship between the structure and bioactivity of chosen groups of peptides including pheromones, anticancer and antibiotic peptides, and peptides which inhibit neuronal nitric oxide synthase. It would be of national benefit if any of these peptides have applied application, e.g. if we can use the sex pheromone of the cane toad to reduce its population, or if we can produce an anticancer active peptide of clinical applicability.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100001
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
An advanced thermogravimetric analysis system for world-leading research in clean energy, catalysis, material science and nanotechnology. Many chemical reactions occurring in solid materials during heating significantly affect the materials' stability, and subsequently affects the processes of production of clean energy, material synthesis, catalyst preparation, and nanotechnology. No equipment currently exists in Australia that will mitigate the wide range of conditions in such reactions in ma ....An advanced thermogravimetric analysis system for world-leading research in clean energy, catalysis, material science and nanotechnology. Many chemical reactions occurring in solid materials during heating significantly affect the materials' stability, and subsequently affects the processes of production of clean energy, material synthesis, catalyst preparation, and nanotechnology. No equipment currently exists in Australia that will mitigate the wide range of conditions in such reactions in materials processing. This situation impedes research progress in Australia, disadvantages Australian research students, and ultimately makes our research less competitive internationally. The establishment of the proposed apparatus will increase the competitiveness of Australian science and engineering, and contribute to the development of new Australian technologies that are important to the Australian economy and to environmental sustainability.Read moreRead less
Beyond oceanography: behavior as a tool to uncover ocean complexity. It is crucial that Australia remains a world leader in marine biology and ecology and continues to preserve the uniqueness of its marine environment through the development of integrated inter-disciplinary research projects. This project will open a new area of research at both the national and international levels through the first integrated approach of the behavioural mechanisms that rule the base of the ocean food web struc ....Beyond oceanography: behavior as a tool to uncover ocean complexity. It is crucial that Australia remains a world leader in marine biology and ecology and continues to preserve the uniqueness of its marine environment through the development of integrated inter-disciplinary research projects. This project will open a new area of research at both the national and international levels through the first integrated approach of the behavioural mechanisms that rule the base of the ocean food web structures and functions. The present work is also expected to open new perspectives in fields such as biological oceanography, microbial ecology, plankton ecology, behavioural ecology through the exploration of previously untapped areas of research.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775649
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
An Integrated Multi-Node Microfluidics Facility. The establishment of the proposed facility will enhance Australia's position in microfluidics research, thus contributing to all National Priority areas, particularly the National Priority area 3 through advancement in breakthrough science and frontier technologies. In addition to researchers from participating institutions, the Facility will be made available to other Australian researchers from non-participating organisations at minimum cost. Th ....An Integrated Multi-Node Microfluidics Facility. The establishment of the proposed facility will enhance Australia's position in microfluidics research, thus contributing to all National Priority areas, particularly the National Priority area 3 through advancement in breakthrough science and frontier technologies. In addition to researchers from participating institutions, the Facility will be made available to other Australian researchers from non-participating organisations at minimum cost. The socio-economic potentials of the research carried out using the proposed facility are significant and include: R&D development, small scale high technology manufacture, exports, and improved methods of biochemical processing and medical diagnostics.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100010
Funder
Australian Research Council
Funding Amount
$720,000.00
Summary
A 5-D Correlative Imaging Platform: Combining the strengths of light and electron microscopy. This will be Australia's first dedicated five-dimensional multiphoton-microscopy platform, allowing observation of dynamic structures across different length and time scales under controlled temperatures, followed by high-resolution electron microscopy studies on the same samples. This platform will provide a unique characterisation tool to Australia's top-flight investigators, and so contribute to the ....A 5-D Correlative Imaging Platform: Combining the strengths of light and electron microscopy. This will be Australia's first dedicated five-dimensional multiphoton-microscopy platform, allowing observation of dynamic structures across different length and time scales under controlled temperatures, followed by high-resolution electron microscopy studies on the same samples. This platform will provide a unique characterisation tool to Australia's top-flight investigators, and so contribute to the nation's research priorities. It will enable: fundamental studies of cancer, neural diseases and immune disorders; the development of frontier technologies, such as smart nanomaterials, biosensors and targeted drug delivery; and applied research to help plants and soils adapt to climate variability, and to increase sustainable use of water.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL0992247
Funder
Australian Research Council
Funding Amount
$2,988,295.00
Summary
Advances at the frontiers of subatomic physics and cross-disciplinary applications of the associated techniques. The candidate is an international scientific leader, in terms of his own research, his responsibilities within the United States Department of Energy (DoE) and his role as Chair of the International Union of Pure and Applied Physics (IUPAP) Working Group on International Cooperation in Nuclear Physics. His return to South Australia to establish a major new research centre in the physi ....Advances at the frontiers of subatomic physics and cross-disciplinary applications of the associated techniques. The candidate is an international scientific leader, in terms of his own research, his responsibilities within the United States Department of Energy (DoE) and his role as Chair of the International Union of Pure and Applied Physics (IUPAP) Working Group on International Cooperation in Nuclear Physics. His return to South Australia to establish a major new research centre in the physical sciences will dramatically enhance the State's reputation in science and engineering, an essential component of its contribution to the nation's defence. It will underline Australia's commitment to contribute its share to advancing fundamental science. The involvement of senior researchers from fields as diverse as applied optics and mathematical biology will ensure that the opportunities for cross-disciplinary research are fully exploited.Read moreRead less
The geometry of impossible, or contradictory objects and its applications to computing and cognition. The principal aim is pure research, the increase of knowledge within the Theory of Inconsistency and particularly its mathematical aspects, to be available to the national and world community. Additionally, a new stock of hitherto-unseen images (still, moving and three-dimensional) will be constructed in a virtual reality environment. In addition to enhancing Australia's strong reputation in log ....The geometry of impossible, or contradictory objects and its applications to computing and cognition. The principal aim is pure research, the increase of knowledge within the Theory of Inconsistency and particularly its mathematical aspects, to be available to the national and world community. Additionally, a new stock of hitherto-unseen images (still, moving and three-dimensional) will be constructed in a virtual reality environment. In addition to enhancing Australia's strong reputation in logic, there are spin-offs for mathematics, cognitive science, computer studies, and the arts and entertainment industries.Read moreRead less