Studies of Group 15 complexes of the Lanthanoids and Group 2 metals-An unexploited field of research. The project will initially explore new amido chemisty of the lanthanoids. This chemistry will develop towards complexes with lanthanoid-or Group 2-phosphorus, -arsenic, -antimony or -bismuth connectivities. This chemistry is surprisingly underdeveloped given the wealth of applications found for oxo and amido complexes of the same metals. Structural studies involving the complexes using cutting e ....Studies of Group 15 complexes of the Lanthanoids and Group 2 metals-An unexploited field of research. The project will initially explore new amido chemisty of the lanthanoids. This chemistry will develop towards complexes with lanthanoid-or Group 2-phosphorus, -arsenic, -antimony or -bismuth connectivities. This chemistry is surprisingly underdeveloped given the wealth of applications found for oxo and amido complexes of the same metals. Structural studies involving the complexes using cutting edge ligands will reveal interesting coordination modes. The discovery of new reaction pathways will be of interest to the wider chemical community. The chemical reactivity and potential catalytic or luminescent properties of these compounds will be studied and will result in publications in international journals.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0221983
Funder
Australian Research Council
Funding Amount
$900,000.00
Summary
Interface, Particle and Complex Fluid Characterisation Laboratory. This laboratory will provide a state-of-the-art characterisation facility for complex fluids. This will service the needs of 27 research staff and 38 postgraduate students and involve collaboration between twelve major research groups based at the Universities of Melbourne, Newcastle, Monash, La Trobe and RMIT. The facility will enhance the research activities of the collaborating institutions in key strategic areas. The laborat ....Interface, Particle and Complex Fluid Characterisation Laboratory. This laboratory will provide a state-of-the-art characterisation facility for complex fluids. This will service the needs of 27 research staff and 38 postgraduate students and involve collaboration between twelve major research groups based at the Universities of Melbourne, Newcastle, Monash, La Trobe and RMIT. The facility will enhance the research activities of the collaborating institutions in key strategic areas. The laboratory will also act as a facility for undertaking consulting projects with industry groups by the applicants.Read moreRead less
Special Research Initiatives - Grant ID: SR0354474
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Metals in Medicine. Metal-based drugs account for several billion dollars of pharmaceutical sales worldwide, but proportionally much less research and development has focussed on this area than organic drugs. Australia has played a pivotal role in the early development of metal-based pharmaceuticals, which remains a research strength. The dual aims of the initiative are to provide a network for a vibrant industry based around metals in medicine and to improve the health of Australians. The ini ....Metals in Medicine. Metal-based drugs account for several billion dollars of pharmaceutical sales worldwide, but proportionally much less research and development has focussed on this area than organic drugs. Australia has played a pivotal role in the early development of metal-based pharmaceuticals, which remains a research strength. The dual aims of the initiative are to provide a network for a vibrant industry based around metals in medicine and to improve the health of Australians. The initiative will foster national and international cross-disciplinary collaborations to address the impediments holding back Australia's potential to take full advantage of our research strength in metals in medicine.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346515
Funder
Australian Research Council
Funding Amount
$507,000.00
Summary
Fluorescence Detector for the Australian National Beamline Facility. X-ray absorption spectroscopy (XAS) is an extremely important synchrotron radiation tool for determining the local structure around an X-ray absorbing atom. This has many applications in the study of materials, minerals, metal complexes, and metalloproteins and can often be used to obtain information that is not available by other techniques, because structural information can be obtained in the solid or solution state and in ....Fluorescence Detector for the Australian National Beamline Facility. X-ray absorption spectroscopy (XAS) is an extremely important synchrotron radiation tool for determining the local structure around an X-ray absorbing atom. This has many applications in the study of materials, minerals, metal complexes, and metalloproteins and can often be used to obtain information that is not available by other techniques, because structural information can be obtained in the solid or solution state and in mixtures. The current proposal is aimed at introducing new technology into the Australian National Beamline Facility that will greatly improve the quality and quantity of experiments that can be performed and extend studies into dilute solutions and protein samples.Read moreRead less
Special Research Initiatives - Grant ID: SR0354636
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecula ....Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecular scale computations in the fields of nanoscience, biomaterials, biotechnology, biomedical science and environmental science. It will uncover and explore critical new interdisciplinary science and create new molecular-based paradigms that will drive advances in these fields over the next decade.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0560680
Funder
Australian Research Council
Funding Amount
$901,862.00
Summary
Vibrational Spectroscopy Microprobe/FESEM/AFM Imaging of Cells, Tissues and Materials. State-of-the-art vibrational mapping and imaging equipment (integrated with a field-emission scanning electron microscope (FESEM) and an atomic force microscope (AFM)) will provide enabling technologies for cutting-edge research in disease diagnosis, identification of pathogens, mapping of the entry and distribution of pharmaceutics into cells, and materials research. An InVia Renishaw Raman spectrometer (sub ....Vibrational Spectroscopy Microprobe/FESEM/AFM Imaging of Cells, Tissues and Materials. State-of-the-art vibrational mapping and imaging equipment (integrated with a field-emission scanning electron microscope (FESEM) and an atomic force microscope (AFM)) will provide enabling technologies for cutting-edge research in disease diagnosis, identification of pathogens, mapping of the entry and distribution of pharmaceutics into cells, and materials research. An InVia Renishaw Raman spectrometer (sub-micron spatial positioning and micron spatial resolution) will be interfaced to an FEI Quanta FESEM for combined Raman (spectroscopic), EDS and SEM (morphological) imaging/mapping at the sub-cellular level. Complementary new-generation Raman and IR spectrometer upgrades will provide an integrated world-class equipment platform.Read moreRead less
A new G-protein coupled receptor target for conotoxins. We aim to understand the interaction between venom components from the marine cone snail, a major source of potential drug leads, and a key receptor in nerve cell signalling. This receptor plays a role in many nervous system functions and has been proposed as a target for treating a range of diseases including pain, depression and drug addiction. It is critical that we understand this interaction so we can fully exploit the potential of the ....A new G-protein coupled receptor target for conotoxins. We aim to understand the interaction between venom components from the marine cone snail, a major source of potential drug leads, and a key receptor in nerve cell signalling. This receptor plays a role in many nervous system functions and has been proposed as a target for treating a range of diseases including pain, depression and drug addiction. It is critical that we understand this interaction so we can fully exploit the potential of these molecules as drug leads. The potential exists for multibillion dollar markets for these new drugs that could provide significant economic benefits to Australia.Read moreRead less
ARC Centre of Excellence - Centre for Free Radical Chemistry and Biotechnology. Free radical chemistry is of increasing importance in the manufacture of improved plastics, paints and related materials, in helping restrict oxidative processes that can lead to adverse human health and also to the degradation of important industrial materials. The research will contribute to promoting & maintaining good health by developing new methods for reducing the impacts of ageing as well as in the treatment ....ARC Centre of Excellence - Centre for Free Radical Chemistry and Biotechnology. Free radical chemistry is of increasing importance in the manufacture of improved plastics, paints and related materials, in helping restrict oxidative processes that can lead to adverse human health and also to the degradation of important industrial materials. The research will contribute to promoting & maintaining good health by developing new methods for reducing the impacts of ageing as well as in the treatment of several life-threatening conditions such as stroke. Industrial applications include better surface coatings for preserving metals, and additives to improve the quality and shelf life of beer and wines.Read moreRead less
Special Research Initiatives - Grant ID: SR0354741
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Quantum Many-Body Systems Network: Breakthrough Science and Frontier Technologies. This Initiative will bring together leading researchers with complementary expertise in mathematics and the enabling sciences to form a Network fostering world leading fundamental research and innovation in quantum many-body systems. The collaborative effort between mathematicians with powerful and sophisticated new techniques and physicists and chemists with deep insight into the challenges and opportunities of t ....Quantum Many-Body Systems Network: Breakthrough Science and Frontier Technologies. This Initiative will bring together leading researchers with complementary expertise in mathematics and the enabling sciences to form a Network fostering world leading fundamental research and innovation in quantum many-body systems. The collaborative effort between mathematicians with powerful and sophisticated new techniques and physicists and chemists with deep insight into the challenges and opportunities of the quantum realm will lead to breakthrough science of vital importance to the development of frontier technologies in Australia. This Network will also place a strong emphasis on research training, the mentoring of early career researchers and establishing collaborations with leading international research groups and networks.
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Nanoporous Epoxy Thermosets via Microphase Separation of Block Copolymers. This project has many expected outcomes and benefits to Australia: (1) Development of the first technology to produce nanoporous epoxy thermosets (i.e. epoxy nanofoams) that may have many applications in microelectronics, optical waveguides and biological separations; (2) Providing impetus for an advanced materials synthesis and manufacturing industry for Australia and contributing to the Frontier Technologies National Re ....Nanoporous Epoxy Thermosets via Microphase Separation of Block Copolymers. This project has many expected outcomes and benefits to Australia: (1) Development of the first technology to produce nanoporous epoxy thermosets (i.e. epoxy nanofoams) that may have many applications in microelectronics, optical waveguides and biological separations; (2) Providing impetus for an advanced materials synthesis and manufacturing industry for Australia and contributing to the Frontier Technologies National Research Priority-Advanced Materials Priority Goals; (3) The development of new niche markets with these new materials and the new technologies, which is an excellent vehicle for Australia to move to a high-value added industrial portfolio that maximises return and promotes job growth.Read moreRead less